Results 111 to 120 of about 25,827 (208)
Ecology and Evolution, Volume 16, Issue 3, March 2026.ABSTRACT Global environmental change affects organisms, including their physiology. In freshwater ecosystems, where migration is limited, populations often rely on phenotypic plasticity to respond. While transcriptomics has been widely used to study stress responses at the molecular level, less is known about the proteome, which reflects post ...
João M. Moreno +5 more
wiley +1 more source
Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control
The Journal of Physiology, EarlyView.
Richard J. A. Wilson +1 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 2, March 2026.This study proposes the upcycling of oriental melon (Cucumis melo var. makuwa) stems, typically discarded as agricultural waste, into a bioactive extract with functional potential. CMSE ameliorates high‐fat‐diet‐induced obesity and fatty liver, contributing to the restoration of metabolic health by enhancing the expression of thermogenesis‐related ...
Myeong‐Jin Kim +10 more
wiley +1 more source
Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions
Food Science &Nutrition, Volume 14, Issue 3, March 2026.Natural products such as EGCG, berberine, curcumin, and capsaicin modulate key metabolic pathways including AMPK activation, adipogenesis inhibition, and inflammatory signaling. While clinical trials demonstrate modest benefits on body weight and metabolic parameters, translational challenges related to bioavailability, dose feasibility, and regulatory
Ohoud M. Marie +1 more
wiley +1 more source
Heart Failure: Epidemiology, Pathophysiology, and Management
MedComm, Volume 7, Issue 3, March 2026.This article takes calcium homeostasis as the point of departure to provide an overview of heart failure from three perspectives—epidemiology, pathophysiological mechanisms, and management strategies—and summarizes the current unmet needs and future directions in the field. ABSTRACT Heart failure (HF) is one of the leading causes of hospitalization and
Yujian Fan +9 more
wiley +1 more source
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
MedComm – Oncology, Volume 5, Issue 1, March 2026.Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
Acta Physiologica, Volume 242, Issue 3, March 2026.ABSTRACT Aim Controversy exists on which metabolites determine the exaggerated exercise pressor reflex (EPR) in peripheral artery disease (PAD). In decerebrated rats, we investigated the role played by lactate and hydrogen ions in a model of PAD, which was simulated by ligating the femoral artery for 72 h before the start of the experiment.
Guillaume P. Ducrocq +3 more
wiley +1 more source
UVB Upregulates Inflammatory Cytokines in Rosacea Cell Model by Promoting the Expression of TRPVs and TLR2. [PDF]
Immunotargets TherXie Y, Hu Y, Huang J, Liu J, Zhang Q.
europepmc +1 more source
Coumarins and Their Derivatives in Animal Models of Asthma: A Systematic Review
Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.Mast cells drive early allergic asthma by releasing histamine, interleukins and prostaglandins, causing airway hyperresponsiveness, mucus overproduction and inflammation. These events sustain symptoms and promote structural remodelling, contributing to the progression of the disease.
Iêda Maria dos Santos +3 more
wiley +1 more source