Results 61 to 70 of about 5,561 (208)
Advances in Atopic Dermatitis Treatment: From Pathogenesis to Natural Product-Based Therapies. [PDF]
Phytother ResNPs improve atopic dermatitis mainly include flavonoids, phenols, glycosides, alkaloids, and others. ABSTRACT Atopic dermatitis (AD), a widespread and chronic inflammatory skin disorder, profoundly affects patients' quality of life, imposes significant psychological strain, and adds to the public health burden.
Fan X +8 more
europepmc +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley +1 more source
Synthesis of diversely functionalised 2,2-disubstituted oxetanes: fragment motifs in new chemical space [PDF]
, 2015 Novel oxetane motifs incorporating diverse functional groups on the ring are readily accessed by an O–H insertion/cyclisation strategy.
Bull, JA, Croft, RA, Davis, OA
core +1 more source
The Xenopus tropicalis orthologue of TRPV3 is heat sensitive [PDF]
Journal of General Physiology, 2015 Thermosensitive members of the transient receptor potential (TRP) family of ion channels (thermal TRP channels) play a crucial role in mammalian temperature sensing. Orthologues of these channels are present in lower vertebrates and, remarkably, some thermal TRP orthologues from different species appear to mediate opposing responses to temperature. For
Liu, Beiying, Qin, Feng
openaire +2 more sources
What do we know about the transient receptor potential vanilloid 2 (TRPV2) ion channel? [PDF]
, 2013 Transient receptor potential (TRP) ion channels are emerging as a new set of membrane proteins involved in a vast array of cellular processes and regulated by a large number of physical and chemical stimuli, which involves them with sensory cell ...
Doñate-Macian, Pau +2 more
core +1 more source
Novel Technologies for Exploring the Skin–Brain Axis
Advanced Sensor Research, Volume 5, Issue 2, February 2026.The skin–brain axis mediates bidirectional communication between cutaneous physiology and the nervous system, influencing sensation, inflammation, and disease. This review surveys emerging microsensor, nanosensor, and bioelectronic technologies integrated with advanced skin and neural models, highlighting multimodal, real‐time strategies to decode ...
Dahiana Mojena Medina, Francesca Santoro
wiley +1 more source
Pharmaceutical Biology, 2017 Context: Spirodela polyrhiza (L.) Schleid. (Lemnaceae), Spirodelae Herba (SH), has been known to relieve inflammation, urticaria and skin symptoms including pruritus, eczema and rash.
Joo Hyun Nam +5 more
doaj +1 more source
, 2007 Cooling of the skin has long been thought to be beneficial in pain states but intense cold is clearly noxious. Does cooling lead to pain or gain? Rapid progress in this controversy has been made since the discovery of specific ion channels of the ...
Allchorne, A +5 more
core +1 more source
Advanced Science, Volume 13, Issue 7, 3 February 2026.This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang +6 more
wiley +1 more source
The significant expression of TRPV3 in nasal polyps of eosinophilic chronic rhinosinusitis
Allergology International, 2017 Background: The number of patients with eosinophilic chronic rhinosinusitis (ECRS) has been increasing in recent years in Japan. In ECRS, nasal polyps recur immediately after endoscopic sinus surgery.
Takahiro Tokunaga +7 more
doaj +1 more source