Results 71 to 80 of about 22,113 (163)

Protective efficacy of isometamidium chloride and diminazene aceturate against natural Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population in Uganda

open access: yesOnderstepoort Journal of Veterinary Research, 2004
The protective efficacy of isometamidium chloride (ISMM) and diminazene aceturate (DIM) against Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population was assessed in southeast Uganda.
J.W. Magona   +3 more
doaj   +1 more source

The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa

open access: yesThe FEBS Journal, Volume 293, Issue 4, Page 948-958, February 2026.
Metacaspases are Ca2+‐dependent cysteine proteases whose structural characteristics, particularly calcium binding and autocatalytic processing, govern their activation and biological functions. These enzymes differ among microorganisms and regulate their cell cycles, making them excellent targets for drug development.
Ane C. M. Duarte   +9 more
wiley   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

open access: yesJournal of Microscopy, Volume 301, Issue 2, Page 280-329, February 2026.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz   +4 more
wiley   +1 more source

In vitro antitrypanosomal potential of chloroform leaf extract of Punica granatum L. on Trypanosoma brucei brucei and Trypanosoma evansi

open access: yesMicrobiology Research, 2017
The plant Pomegranate (Punica granatum Linn.) selected for this study is native to the region of Eurasia. The objective of this study was to evaluate the antitrypanosomal potential of the plant against Trypanosoma brucei brucei (T.b.
Muhammad Muhsin Fathuddin   +1 more
doaj   +1 more source

Consistent detection of Trypanosoma brucei but not T. congolense DNA in faeces of experimentally infected cattle

open access: yesScientific Reports
Animal African trypanosomiasis (AAT) is a significant food security and economic burden in sub-Saharan Africa. Current AAT empirical and immunodiagnostic surveillance tools suffer from poor sensitivity and specificity, with blood sampling requiring ...
Isabel Saldanha   +10 more
doaj   +1 more source

Résistance médicamenteuse d'isolats récents de Trypanosoma brucei et Trypanosoma congolense

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1988
Des études ont été menées sur des souris pour déterminer la sensibilité aux médicaments d’isolats récents de Trypanosoma brucei et Trypanosoma congolense. Chacune des onze souches de T. congolense et des cinq souches de T. brucei, toutes isolées sur des
R.A. Joshua
doaj   +1 more source

Multiple evolutionary origins of Trypanosoma evansi in Kenya.

open access: yesPLoS Neglected Tropical Diseases, 2017
Trypanosoma evansi is the parasite causing surra, a form of trypanosomiasis in camels and other livestock, and a serious economic burden in Kenya and many other parts of the world.
Christine M Kamidi   +8 more
doaj   +1 more source

Route of inoculation influences Trypanosoma congolense and Trypanosoma brucei brucei virulence in Swiss white mice.

open access: yesPLoS ONE, 2019
Experiments on infections caused by trypanosomes are widely performed in Swiss white mice through various inoculation routes. To better understand the effect of route of trypanosome inoculation on disease outcomes in this model, we characterised the ...
Kariuki Ndungu   +8 more
doaj   +1 more source

Genetic Diversity in the Diminazene Resistance-Associated P2 Adenosine Transporter-1 (AT-1) Gene of Trypanosoma evansi

open access: yesAnimals
Trypanosomes are parasitic protozoa that cause severe diseases in humans and animals. The most important species of Trypanosmes include Trypanosoma evansi and Trypanosoma brucei gambiense.
Shoaib Ashraf   +6 more
doaj   +1 more source

Q586B2 is a crucial virulence factor during the early stages of Trypanosoma brucei infection that is conserved amongst trypanosomatids

open access: yesNature Communications
Human African trypanosomiasis or sleeping sickness, caused by the protozoan parasite Trypanosoma brucei, is characterized by the manipulation of the host’s immune response to ensure parasite invasion and persistence. Uncovering key molecules that support
Benoit Stijlemans   +25 more
doaj   +1 more source

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