Results 41 to 50 of about 11,887 (139)
Journal of the American Medical Association, 1915 Patient. —I. S., No. 181943, man, negro, aged 35, native of Cape Verde Islands, was admitted to the Massachusetts State Infirmary from New Bedford, Oct. 7, 1914. The patient was unable to understand English, and as a good Portuguese interpreter was not available at the time, his history could not be obtained.
openaire +1 more source
Parasites & Vectors, 2019 African trypanosomes cause human African trypanosomiasis and animal African trypanosomiasis. They are transmitted by tsetse flies in sub-Saharan Africa.
Mathieu Cayla +4 more
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Tropical Medicine and Infectious Disease, 2020 Current anti-trypanosomal therapies suffer from problems of longer treatment duration, toxicity and inadequate efficacy, hence there is a need for safer, more efficacious and ‘easy to use’ oral drugs.
Srinivasa P S Rao +13 more
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In Vitro Mechanism of Action of Acanthospermum hispidum in Trypanosoma brucei
Advances in Pharmacological and Pharmaceutical Sciences, 2022 African trypanosomiasis is a major neglected tropical disease with significant health and economic concerns in sub-Saharan Africa. In the absence of vaccines for African trypanosomiasis, there is a consideration for alternative sources of chemotherapy ...
Aboagye Kwarteng Dofuor +4 more
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A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction
Microbiology SpectrumTrypanosoma brucei is a protozoan parasite that causes human and animal African trypanosomiases (HAT and AAT). Cardiac symptoms are commonly reported in HAT patients, and intracardiac parasites with accompanying myocarditis have been observed in both ...
Nathan P. Crilly +7 more
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Pharmacological Approaches to Antitrypanosomal Chemotherapy
Memorias do Instituto Oswaldo Cruz, 1999 There is an urgent need for new drugs for the chemotherapy of human African trypanosomiasis, Chagas disease and leishmaniasis. Progress has been made in the identification and characterization of novel drug targets for rational chemotherapy and ...
Simon L Croft
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Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2015 Tsetse and trypanosomiasis (T&T) remain endemic in many countries, although many efforts have been made in recent decades within the framework of the Pan-African Tsetse and Trypanosomiasis Eradication Campaign (PATTEC) Initiative, and despite progress ...
Hassane H. Mahamat
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Anilinoquinoline based inhibitors of trypanosomatid proliferation.
PLoS Neglected Tropical Diseases, 2018 We recently reported the medicinal chemistry re-optimization of a series of compounds derived from the human tyrosine kinase inhibitor, lapatinib, for activity against Plasmodium falciparum.
Lori Ferrins +11 more
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Chemotherapy of Human African Trypanosomiasis
Interdisciplinary Perspectives on Infectious Diseases, 2009 Human Africa trypanosomiasis is a centuries-old disease which has disrupted sub-Saharan Africa in both physical suffering and economic loss. This article presents an update of classic chemotherapeutic agents, in use for >50 years and the recent ...
Cyrus J. Bacchi
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