Results 61 to 70 of about 222,637 (336)
The Saudi Journal of Gastroenterology, 2017 Background/Aim: We investigated the association between blood amino acid concentration changes caused by elemental diet (ED) and their relationship to its therapeutic effect. Patients and Methods: Patients with active Crohn's disease (CD) followed ED for
Masakazu Nakano +5 more
doaj +1 more source
Evaluating force field accuracy with long-time simulations of a tryptophan zipper peptide [PDF]
, 2010 We have combined a custom implementation of the fast multiple-time-stepping LN integrator with parallel tempering to explore folding properties of small peptides in implicit solvent on the time scale of microseconds. We applied this algorithm to the synthetic {\beta}-hairpin trpzip2 and one of its sequence variants W2W9.
arxiv +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objectives This study sought to evaluate proteomic, metabolomic, and immune signatures in the cerebrospinal fluid of individuals with Down Syndrome Regression Disorder (DSRD). Methods A prospective case–control study comparing proteomic, metabolomic, and immune profiles in individuals with DSRD was performed.
Jonathan D. Santoro +12 more
wiley +1 more source
A superconducting NbN detector for neutral nanoparticles [PDF]
Nanotechnology 20, 45501, 2009, 2014 We present a proof-of-principle study of superconducting single photon detectors (SSPD) for the detection of individual neutral molecules/nanoparticles at low energies. The new detector is applied to characterize a laser desorption source for biomolecules and it allows to retrieve the arrival time distribution of a pulsed molecular beam containing the ...
arxiv +1 more source
Tryptophan in Nutrition and Health
International Journal of Molecular Sciences, 2022 Tryptophan is a rate-limiting essential amino acid and a unique building block of peptides and proteins [...]
Poeggeler, Burkhard +5 more
openaire +3 more sources
Advanced Biology, EarlyView.Coacervation driven by liquid‐liquid phase separation (LLPS) of biopolymers has garnered increasing attention in biology since this leads to the formation of membraneless organelles capable of performing essential yet largely unknown functions. This review highlights recent advances in coacervates (artificial condensates) composed of low‐molecular ...
Sayuri L. Higashi, Masato Ikeda
wiley +1 more source
Journal of Biological Chemistry, 1975 We investigated how changes in tryptophan pyrrolase activity and tryptophan loads affect the breakdown of tryptophan was estimated by injecting rats with [ring-2-14-C]tryptophan and measuring respiratory 14-CO2. We concluded, contrary to previous reports, that induction of tryptophan pyrrolase definitely will increase the rate of tryptophan breakdown ...
S N Young, T L Sourkes
openaire +3 more sources
Toward Design Principles for Biomolecular Condensates for Metabolic Pathways
Advanced Biology, EarlyView.Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André +3 more
wiley +1 more source
The Feasibility of Coherent Energy Transfer in Microtubules [PDF]
Journal of The Royal Society Interface 2014, 11: 20140677, 2014 It was once purported that biological systems were far too warm and wet to support quantum phenomena mainly due to thermal effects disrupting quantum coherence. However recent experimental results and theoretical analyses have shown that thermal energy may assist, rather than disrupt, quantum coherence, especially in the dry hydrophobic interiors of ...
arxiv +1 more source
Maillard Type Reaction for Electroless Copper Plating onto Ceramic Nanoparticles
Advanced Engineering Materials, EarlyView.This work presents the manufacturing of copper‐plated ceramic nanoparticles in an environmentally friendly way. Supported by organic functionalizations with pectin an electroless plating step can be performed. Sustainable reagents like xylose, and several amino acids are used for the reduction process.
Lukas Mielewczyk +8 more
wiley +1 more source