Results 61 to 70 of about 270,080 (298)

Tryptophane in Proteolysis

Annals of Botany, 1902
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Relationship between metabolites of peripheral tryptophan-kynurenine metabolic pathway and clinical symptoms in patients with schizophrenia

Sichuan jingshen weisheng
BackgroundSchizophrenia is a common severe mental disorder with complex pathogenesis. There are few studies on the correlation between kynurenine metabolites in peripheral serum and urine in schizophrenia.ObjectiveTo investigate the concentration of ...
Wu Yue, Xu Yan, Huang Xin, Wang Dake, Huang Chenyun, Liang Sugai   +5 more
doaj   +1 more source

Effects of a commercial dose of L-tryptophan on plasma tryptophan concentrations and behaviour in horses

, 2008
Reasons for performing the study: L-tryptophan is a common ingredient in equine calmative products, but its effectiveness has not been demonstrated in horses.
Harris, P. A., Sillence, M. N., Munn, K. J., Davidson, H.P.B., Li, Xiuhua, Noble, G. K., Noble, Glenys, Harris, Patricia, Li, X., Brockwell, Y.M., Zhang, D., Munn, Kellie, Brockwell, Y. M., Zhang, Dagong, Davidson, H. R. B., Sillence, Martin   +15 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Investigations of microbiota composition and neuroactive pathways in association with symptoms of stress and depression in a cohort of healthy women

Frontiers in Cellular and Infection Microbiology
BackgroundDespite mounting evidence of gut-brain involvement in psychiatric conditions, functional data remain limited, and analyses of other microbial niches, such as the vaginal microbiota, are lacking in relation to mental health.
Zahra Bashir, Zahra Bashir, Zahra Bashir, Luisa W. Hugerth, Luisa W. Hugerth, Maria Christine Krog, Maria Christine Krog, Maria Christine Krog, Stefanie Prast-Nielsen, Gabriella Edfeldt, Fredrik Boulund, Fredrik Boulund, Simon Rønnow Schacht, Inge Tetens, Lars Engstrand, Lars Engstrand, Ina Schuppe-Koistinen, Ina Schuppe-Koistinen, Emma Fransson, Emma Fransson, Henriette Svarre Nielsen, Henriette Svarre Nielsen, Henriette Svarre Nielsen, Henriette Svarre Nielsen   +23 more
doaj   +1 more source

MRI Relaxivity Changes of the Magnetic Nanoparticles Induced by Different Amino Acid Coatings

Nanomaterials, 2020
In this study, we analysed the physico-chemical properties of positively charged magnetic fluids consisting of magnetic nanoparticles (MNPs) functionalised by different amino acids (AAs): glycine (Gly), lysine (Lys) and tryptophan (Trp), and the ...
Iryna Antal, Oliver Strbak, Iryna Khmara, Martina Koneracka, Martina Kubovcikova, Vlasta Zavisova, Martina Kmetova, Eva Baranovicova, Dusan Dobrota   +8 more
doaj   +1 more source

Tryptophan-Tryptophan energy migration as a tool to follow apoflavodoxin folding

, 2008
Submolecular details of Azotobacter vinelandii apoflavodoxin (apoFD) (un)folding are revealed by time-resolved fluorescence anisotropy using wild-type protein and variants lacking one or two of apoFD's three tryptophans.
Mierlo, C.P.M., van, Westphal, Adrie H., van Amerongen, H., Visser, N.V., Amerongen, H., van, van Hoek, Arie, Hoek, A., van, Visser, Antonie J.W.G., van Amerongen, Herbert, van Hoek, A., Visser, Nina V., Westphal, A.H., van Mierlo, Carlo P.M., Visser, A.J.W.G., van Mierlo, C.P.M.   +14 more
core   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies

Advanced Engineering Materials, EarlyView.
Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo, Daniela Winsley Valereto Friozi, Vinícius de Oliveira, Marcia Cristina Branciforti   +3 more
wiley   +1 more source