Results 21 to 30 of about 1,394 (153)
Regulation of plant gene expression by tsRNAs in response to abiotic stress [PDF]
PeerJObjective Transfer RNA-derived small RNAs (tsRNAs) are emerging regulators of gene expression in response to abiotic stress. This review aims to summarize recent advances in the classification, biogenesis, and biological functions of tsRNAs, with a focus
Chunmei Li +13 more
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Identification of a Fusobacterial RNA-binding protein involved in host small RNA-mediated growth inhibition [PDF]
International Journal of Oral ScienceHost-derived small RNAs are emerging as critical regulators in the dynamic interactions between host tissues and the microbiome, with implications for microbial pathogenesis and host defense.
Pu-Ting Dong +8 more
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Sperm tsRNAs and acquired metabolic disorders [PDF]
Journal of Endocrinology, 2016 Many findings support the hypothesis that metabolic changes associated with environmental factors can be transmitted from father to offspring. The molecular mechanisms underlying the intergenerational transmission of metabolic changes remain to be fully explored.
Menghong, Yan, Qiwei, Zhai
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Journal of Orthopaedic Surgery and Research, 2023 Background Intervertebral disk degeneration (IDD) is a degenerative disease that underlies various musculoskeletal and spinal disorders and is positively correlated with age. tRNA-derived small RNAs (tsRNA), as a new small noncoding RNAs, its function in
Jie Pan +8 more
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Biological functions of tsRNAs and research advances in human disease. [PDF]
Biochem Biophys ReptsRNAs (tRNA-derived small RNAs) are a class of noncoding small RNAs generated by nuclease-specific cleavage of mature tRNAs or their precursors. Since their functional discovery in 2009, tsRNAs have emerged as a research hotspot in molecular biology and medicine because of their unique generation mechanism, tissue-specific expression patterns, and ...
Jiang Y +9 more
europepmc +3 more sources
tsRNAs: new players in mammalian retrotransposon control [PDF]
Cell Research, 2017 A recent study led by Professor Rob Martienssen in Cell showed that 3'-tRNA-derived small RNAs can suppress long terminal repeat retrotransposon activity in mammalian cells by mechanisms independent of DNA-associated epigenetic marks, suggesting how the genome may defend itself from retrotransposon invasion during epigenetic reprogramming.
Zhang, Yunfang, Shi, Junchao, Chen, Qi
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Metazoan tsRNAs: Biogenesis, Evolution and Regulatory Functions [PDF]
Non-Coding RNA, 2019 Transfer RNA-derived small RNAs (tsRNAs) are an emerging class of regulatory non-coding RNAs that play important roles in post-transcriptional regulation across a variety of biological processes. Here, we review the recent advances in tsRNA biogenesis and regulatory functions from the perspectives of functional and evolutionary genomics, with a focus ...
Shengqian Dou, Yirong Wang, Jian Lu
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Stem Cell Research & Therapy, 2020 Background Transfer RNA-derived small RNAs (tsRNAs) are a recently discovered form of non-coding RNA capable of regulating myriad physiological processes.
Tao Wang +5 more
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tsRNAs: The Swiss Army Knife for Translational Regulation [PDF]
Trends in Biochemical Sciences, 2019 tRNA-derived small RNAs (tsRNAs, or tRFs) are a new category of regulatory noncoding RNAs with versatile functions. Recent emerging studies have begun to unveil distinct features of tsRNAs based on their sequence, RNA modifications, and structures that differentially impact their functions towards regulating multiple aspects of translational control ...
Junchao Shi +3 more
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Small regulatory RNAs: from bench to bedside – a keystone symposia meeting report
RNA Biology, 2023 The Keystone Symposium ‘Small Regulatory RNAs: From Bench to Bedside’ was held in Santa Fe, New Mexico from May 1–4, 2022. The symposium was organized by Frank J. Slack, Jörg Vogel, Ivan Martinez and Karyn Schmidt, and brought together scientists working
Soo Mi Lee +3 more
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