Digging out the biology properties of tRNA-derived small RNA from black hole [PDF]
Frontiers in Genetics, 2023 An unique subclass of functional non-coding RNAs generated by transfer RNA (tRNA) under stress circumstances is known as tRNA-derived small RNA (tsRNA).
Hengmei Shi +7 more
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Comprehensive Analysis of a tRNA-Derived Small RNA in Colorectal Cancer [PDF]
Frontiers in Oncology, 2021 Colorectal cancer often presents as a highly variable disease with myriad forms that are at times difficult to detect in early screenings with sufficient accuracy, for which novel diagnostic methods are an attractive and valuable area of improvement.
Yong Zhu +12 more
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Exosomal tRNA-derived small RNA as a promising biomarker for cancer diagnosis [PDF]
Molecular Cancer, 2019 tRNA-derived small RNA (tsRNA) is a novel regulatory small non-coding RNA and participates in diverse physiological and pathological processes. However, the presence of tsRNAs in exosome and their diagnostic potential remain unclear.
Lei Zhu +11 more
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Life, 2015 This review will summarise the recent discoveries and current state of research on short noncoding RNAs derived from tRNAs—known as tRNA-derived fragments (tRFs).
Simon P. Keam, Gyorgy Hutvagner
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Computational Approaches to tRNA-Derived Small RNAs
Non-Coding RNA, 2017 tRNA-derived small RNAs (tDRs) are a group of small, non-coding RNAs derived from transfer RNAs (tRNAs). They can be classified as tRNA halves and tRNA-derived small RNA fragments (tRFs). Accumulating experimental evidence suggests their functional roles
Wei-Lin Xu +4 more
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The production and secretion of tRNA-derived RNA fragments in the corn smut fungus Ustilago maydis
Frontiers in Fungal Biology, 2022 The biogenesis of small non-coding RNAs is a molecular event that contributes to cellular functions. The basidiomycete fungus Ustilago maydis is a biotrophic pathogen parasitizing maize.
Rei Yoshimoto +3 more
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A tRNA-Derived Small RNA Regulates Ribosomal Protein S28 Protein Levels after Translation Initiation in Humans and Mice [PDF]
Cell Reports, 2019 Summary: tRNA-derived small RNAs (tsRNAs) have been implicated in many cellular processes, yet the detailed mechanisms are not well defined. We previously found that the 3′ end of Leu-CAG tRNA-derived small RNA (LeuCAG3′tsRNA) regulates ribosome ...
Hak Kyun Kim +8 more
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The Liver Fluke Opisthorchis felineus Exosomal tRNA-Derived Small RNAs as Potential Mediators of Host Manipulation [PDF]
BiomoleculesThe role of extracellular vesicle non-coding RNAs in host–parasite interactions remains poorly understood, particularly for human liver flukes. Although tRNA-derived small RNAs (tsRNAs) are emerging as new regulatory molecules in parasite exosomes, they ...
Ekaterina Lishai, Maria Pakharukova
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Menstrual cycle-dependent expression of tRNA-derived fragments in healthy human endometrium and uterine fluid-derived extracellular vesicles [PDF]
BMC GenomicsThe human endometrium undergoes dynamic cyclical remodeling across the menstrual cycle to establish receptivity for embryo implantation. While microRNAs are established regulators of endometrial function and embryo–maternal communication, the ...
Apostol Apostolov +8 more
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tRNA-Derived Small RNA: A Novel Regulatory Small Non-Coding RNA. [PDF]
Genes (Basel), 2018 Li S, Xu Z, Sheng J.
europepmc +2 more sources