Results 11 to 20 of about 414,638 (260)
Ontogeny of Tumor-Associated Macrophages [PDF]
Frontiers in Immunology, 2019 Tumor-associated macrophages (TAM) represent the main immune cell population of the tumor microenvironment in most cancer. For decades, TAM have been the focus of intense investigation to understand how they modulate the tumor microenvironment and their ...
Marie Laviron, Alexandre Boissonnas
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Immunotherapy Targeting Tumor-Associated Macrophages [PDF]
Frontiers in Medicine, 2020 Macrophages are phagocytic cells that play a broad role in maintaining body homeostasis and defense against foreign pathogens; whereas tumor-associated macrophages (TAMs) support tumor growth and metastasis by promoting cancer cell proliferation and ...
Yafei Liu, Rongsi Wang
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Targeting Tumor-Associated Macrophages for Imaging
Pharmaceutics, 2022 As an important component of the tumor immune microenvironment (TIME), tumor-associated macrophages (TAMs) occupy a significant niche in tumor margin aggregation and respond to changes in the TIME.
Jiahao Hu, Xiaoling Xu, Yongzhong Du
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Tumor Associated Macrophages in Kidney Cancer [PDF]
Analytical Cellular Pathology, 2016 Tumor associated macrophages (TAMs) are an important element of tumor stroma. They originate from blood monocytes attracted by chemokines and cytokines produced by tumor cells and, being instructed by tumor microenvironment, develop into potent tumor ...
Olga V. Kovaleva +3 more
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Tumor‐associated macrophages in immunotherapy [PDF]
The FEBS Journal, 2021 Tumor‐associated macrophages (TAMs) are essential components of the tumor microenvironment involved in the progression and metastasis of cancer. They are intimately involved in angiogenesis and immunosuppression in normal and malignant tissues, as well as pro‐fibrotic activities.
Shijia Yan, Guohui Wan
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Tumor-associated macrophages [PDF]
Current Biology, 2020 Cassetta and Pollard introduce tumor-associated macrophages and discuss their origin, diversity, function and plasticity.
Cassetta, Luca, Pollard, Jeffrey
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Tumor-associated macrophages in osteosarcoma
Journal of Zhejiang University-SCIENCE B, 2021 Osteosarcoma (OS) is the most common primary bone tumor in children and adolescents. It is an aggressive tumor with a tendency to spread to the lung, which is the most common site of metastasis. Patients with advanced OS with metastases have poor prognoses despite the application of chemotherapy, thus highlighting the need for novel therapeutic targets.
Yi Zhao +4 more
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Metabolic reprograming of tumor-associated macrophages [PDF]
Annals of Translational Medicine, 2020 A large body of scientific evidence corroborated by clinical and animal model experiments indicates that tumor-associated macrophages (TAMs) play a crucial role in tumor development and progression. TAMs are a key immune cell type present in tumor microenvironment (TME) and associated with poor prognosis, drug resistance, enhanced angiogenesis and ...
Puthenveetil, Abhishek, Dubey, Shweta
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Notch Signaling in Macrophages in the Context of Cancer Immunity
Frontiers in Immunology, 2018 Macrophages play both tumor-suppressing and tumor-promoting roles depending on the microenvironment. Tumor-associated macrophages (TAMs) are often associated with poor prognosis in most, but not all cancer.
Tanapat Palaga +5 more
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Biomedicines, 2023 Background: Hepatocellular carcinoma is the sixth most diagnosed malignancy and the fourth most common cause of cancer-related mortality globally. Despite progress in the treatment of liver cancer, nonsurgical treatments remain unsatisfactory, and only ...
Hsin-Lun Lee +6 more
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