Results 21 to 30 of about 414,638 (260)
Chinese Journal of Lung Cancer, 2023 Tumor-associated macrophages (TAMs), characterized by high plasticity, are the most abundant immune cells in the tumor microenvironment (TME). TAMs are recruited to tumor region in response to various TME components such as cytokines, chemokines as well ...
Wenke GE, Weibing WU
doaj +1 more source
The Role of Tumor-Associated Macrophages in Leukemia [PDF]
Acta Haematologica, 2019 In addition to intrinsic factors, leukemia cell growth is influenced by the surrounding nonhematopoietic cells in the leukemic microenvironment, including fibroblasts, mesenchymal stem cells, vascular cells, and various immune cells. Despite the fact that macrophages are an important component of human innate immunity, tumor-associated macrophages ...
Yueyang, Li +4 more
openaire +2 more sources
Role of Tumor-Associated Macrophages in Sarcomas [PDF]
Cancers, 2021 Sarcomas are complex tissues in which sarcoma cells maintain intricate interactions with their tumor microenvironment. Tumor-associated macrophages (TAMs) are a major component of tumor-infiltrating immune cells in the tumor microenvironment and have a dominant role as orchestrators of tumor-related inflammation.
Tomohiro Fujiwara +11 more
openaire +3 more sources
Research and Reports in Urology, 2023 Masakazu Nagata,1 Kazuhiro Ishizaka,1 Touko Asano1,2 1Department of Urology, Teikyo University Hospital Mizonokuchi, Kawasaki, Kanagawa, Japan; 2Department of Urology, Omori Red Cross Hospital, Ota, Tokyo, JapanCorrespondence: Touko Asano, Department of ...
Nagata M, Ishizaka K, Asano T
doaj
Immune Microenvironment in Glioblastoma Subtypes
Frontiers in Immunology, 2018 Glioblastomas (GBMs) are the most common and aggressive primary brain tumors. Due to their malignant growth and invasion into the brain parenchyma coupled with resistance to therapy, GBMs are among the deadliest of all cancers.
Zhihong Chen, Dolores Hambardzumyan
doaj +1 more source
MR imaging of tumor-associated macrophages [PDF]
OncoImmunology, 2012 Tumor associated macrophages (TAMs) in breast cancers foster several aspects of tumor progression and metastasis, and represent a biomarker associated with an unfavorable clinical outcome. As new therapeutic agents selectively targeting leukocytes enter the clinic whose mechanism of action involves diminishing macrophage infiltration or presence in ...
Heike, Daldrup-Link, Lisa M, Coussens
openaire +2 more sources
Origins of tumor-associated macrophages and neutrophils [PDF]
Proceedings of the National Academy of Sciences, 2012 Tumor-associated macrophages (TAMs) and tumor-associated neutrophils (TANs) can control cancer growth and exist in almost all solid neoplasms. The cells are known to descend from immature monocytic and granulocytic cells, respectively, which are produced in the bone marrow.
Cortez-Retamozo, Virna +19 more
openaire +6 more sources
Advances in the Study of Tumor-associated Macrophages in Lung Cancer
Chinese Journal of Lung Cancer, 2022 Lung cancer is one of the malignant tumors with the highest morbidity and mortality in China. Therefore, the research on the treatment of lung cancer is also deepening.
Yanyan QIAO, Enqing FU
doaj +1 more source
Research Progress of M2-type Tumor-associated Macrophages in Lung Cancer
Zhongliu Fangzhi Yanjiu, 2022 Tumor-associated macrophages (TAMs) account for a large proportion in tumor stroma, and can be divided into M1 type (anti-tumoral) and M2 type (pro-tumoral).
WAN Xiaoying, ZHOU Songwen
doaj +1 more source
The impact of hypoxia on tumor-associated macrophages [PDF]
Journal of Clinical Investigation, 2016 The role of tumor-associated macrophages (TAMs) in cancer is often correlated with poor prognosis, even though this statement should be interpreted with care, as the effects of macrophages primarily depend on their localization within the tumor. This versatile cell type orchestrates a broad spectrum of biological functions and exerts very complex and ...
Henze, Anne-Theres, Mazzone, Max
openaire +2 more sources