Results 221 to 230 of about 463,193 (304)

Finely-tuned regulator of DNA repair: FBXW7-185aa may modulate glioblastoma radiosensitization and the tumor immune microenvironment. [PDF]

Transl Oncol
Li Z, Hu N, Zhou S, Guo X, Yang Z, Jing Z, Li H, Tao Y, Hu W, Liang W, Li J, Lyu Y, Fu X, Wang X.   +13 more
europepmc   +1 more source

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

Dynamic Evolution of the Tumor Immune Microenvironment in Malignant Tumors and Emerging Therapeutic Paradigms. [PDF]

MedComm (2020)
Sun Y, Shao C, Duan H, Wang Z, Xu S, Wang C, Xiu J, Liu J, Wang X, Yao X, Gao Y, Yan X.   +11 more
europepmc   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review). [PDF]

Oncol Rep
Qiu M, Lan C, Lin M, Ma H.
europepmc   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Prognostic impact of the lipid metabolism gene AGPAT4 in the tumor immune microenvironment of thyroid cancer. [PDF]

Genomics Inform
Zhu Y, Xu W, Bai X, Qiao Y, Ye D.
europepmc   +1 more source

Cold Atmospheric Plasma‐Activated Decellularized Extracellular Matrix Gel as a Tumor‐Infiltrating Immunoactivation Platform for Post‐Surgical Cancer Immunotherapy

Advanced Materials, EarlyView.
An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang, Mo Chen, Yueyang Deng, Tianqin Ning, Tianwen Luo, Guojun Chen   +5 more
wiley   +1 more source

Immunological profile of the tumor immune microenvironment of upper tract urothelial carcinoma predicts recurrence patterns. [PDF]

Cancer Immunol Immunother
Takahashi K, Ikarashi D, Kitano S, Tamura D, Abe M, Ito A, Shiomi E, Maekawa S, Kato R, Kanehira M, Yanagawa N, Obara W.   +11 more
europepmc   +1 more source

Safe and Localized Lentiviral Gene Delivery via Injectable Mesoporous Scaffolds for Potent Antitumor Immunity

Advanced Materials, EarlyView.
This work introduces an injectable mesoporous silica rod scaffold that confines lentiviral vectors to the injection site, enabling localized dendritic cell recruitment and transduction. The platform sustains antigen expression, promotes robust T‐cell activation, and enhances antitumor immunity.
Thanh Loc Nguyen, Yeon‐ju Kim, Jihye Im, Dong Kwang Min, Hyunsu Shin, Thuy An Trinh, Ngoc Man Phan, Min‐jeong Son, Ji‐yeon Shim, Ye‐lim Lee, Yujeong Ha, Kwang‐il Lim, Jaeyun Kim   +12 more
wiley   +1 more source