Results 11 to 20 of about 22,249 (182)

Twist1 Suppresses Cementoblast Differentiation

open access: yesDentistry Journal, 2018
The transcription factor Twist1 is known to be closely associated with the formation of bone by mesenchymal stem cells and osteoblasts; however, the role of Twist1 in cementogenesis has not yet been determined.
Jung-Sun Moon   +5 more
doaj   +2 more sources

Functional analysis of TWIST1 domains regulating smooth muscle cell phenotype [PDF]

open access: yesFrontiers in Cardiovascular Medicine
IntroductionTWIST1, a bHLH transcription factor, regulates mesenchymal specification, differentiation, proliferation and migration during development and in diseases such as cancer. More recently, genome-wide association studies have identified TWIST1 as
Danielle C. M. Dy   +7 more
doaj   +2 more sources

MiR-337-3p Promotes Adipocyte Browning by Inhibiting TWIST1 [PDF]

open access: yesCells, 2020
The prevalence of metabolic syndrome (MetS) and obesity is an alarming health issue worldwide. Obesity is characterized by an excessive accumulation of white adipose tissue (WAT), and it is associated with diminished brown adipose tissue (BAT) activity ...
Indira G.C. Vonhögen   +8 more
doaj   +4 more sources

TWIST1 is expressed in colorectal carcinomas and predicts patient survival. [PDF]

open access: yesPLoS ONE, 2011
TWIST1 is a transcription factor that belongs to the family of basic helix-loop-helix proteins involved in epithelial-to-mesenchymal transition and invasion processes.
Irene Gomez   +11 more
doaj   +3 more sources

CXCL11 mediates TWIST1-induced angiogenesis in epithelial ovarian cancer

open access: yesTumor Biology, 2017
To investigate the role of TWIST1 in tumor angiogenesis in epithelial ovarian cancer and to identify key molecules involved in angiogenesis. TWIST1 small interfering RNA was transfected into A2780 cells, while a complementary DNA vector was transfected ...
Yu-Jin Koo   +5 more
doaj   +2 more sources

TWIST1 promotes invasion through mesenchymal change in human glioblastoma [PDF]

open access: yesMolecular Cancer, 2010
Background Tumor cell invasion into adjacent normal brain is a mesenchymal feature of GBM and a major factor contributing to their dismal outcomes.
Wakimoto Hiroaki   +13 more
doaj   +2 more sources

Downregulation of miR-22 Contributes to Epithelial-Mesenchymal Transition in Osteosarcoma by Targeting Twist1

open access: yesFrontiers in Oncology, 2020
The epithelial-mesenchymal transition (EMT) is a vital step in osteosarcoma (OS) progression toward metastasis, but the specific molecular events governing this process are incompletely characterized, with miRNAs having increasingly been found to ...
Shu-tao Zhu   +4 more
doaj   +1 more source

miR-151-3p Targets TWIST1 to Repress Migration of Human Breast Cancer Cells. [PDF]

open access: yesPLoS ONE, 2016
TWIST1 is a highly conserved basic helix-loop-helix transcription factor that contributes to cancer metastasis by promoting an epithelial-mesenchymal transition and repressing E-cadherin gene expression in breast cancer.
Ting-Chih Yeh   +7 more
doaj   +1 more source

DataSheet1_A Mixture of Baicalein, Wogonin, and Oroxylin-A Inhibits EMT in the A549 Cell Line via the PI3K/AKT-TWIST1-Glycolysis Pathway.pdf

open access: yes, 2022
Non-small cell lung cancer (NSCLC) is a worldwide disease with a high morbidity and mortality rate, which is most derived from its metastasis. Some studies show that the epithelial–mesenchymal transition (EMT) process promotes lung cancer cell migration ...
Shu Zhao (435198)   +10 more
core   +1 more source

The role of Twist1 in UVB-induced skin carcinogenesis [PDF]

open access: yes, 2021
The transcription factor Twist1 has been reported to be essential for the formation and invasiveness of chemically induced tumors in mouse skin. However, the impact of keratinocyte specific Twist1 deletion on carcinogenesis caused by UVB radiation has ...
Eguiarte-Solomon, Fernando
core   +1 more source

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