Results 31 to 40 of about 259,068 (324)
An interbacterial DNA deaminase toxin directly mutagenizes surviving target populations
eLife, 2021 When bacterial cells come in contact, antagonism mediated by the delivery of toxins frequently ensues. The potential for such encounters to have long-term beneficial consequences in recipient cells has not been investigated. Here, we examined the effects
Marcos H de Moraes +11 more
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A binary effector module secreted by a type VI secretion system [PDF]
EMBO reports, 2021 ABSTRACTGram-negative bacteria use type VI secretion systems (T6SSs) to deliver toxic effector proteins into neighboring cells. Cargo effectors are secreted by binding non-covalently to the T6SS apparatus. Occasionally, effector secretion is assisted by an adaptor protein, although the adaptor itself is not secreted.
Dar, Yasmin +3 more
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The Missing Pieces: The Role of Secretion Systems in Campylobacter jejuni Virulence
Biomolecules, 2023 Campylobacter jejuni is likely the most common bacterial cause of gastroenteritis worldwide, responsible for millions of cases of inflammatory diarrhea characterized by severe abdominal cramps and blood in the stool. Further, C.
Amber D. Gabbert +7 more
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Type VI secretion system [PDF]
Current Biology, 2015 Bacteria employ a variety of tools to survive in a competitive environment. Salomon and Orth describe one such tool-the Type 6 Secretion Systems used by bacteria to deliver a variety of toxins into competing cells.
Salomon, Dor, Orth, Kim
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Vibrio parahaemolyticus T6SS2 effector repertoires
Gut Microbes, 2023 All strains of the marine bacterium Vibrio parahaemolyticus harbor a type VI secretion system (T6SS) named T6SS2, suggesting that this system plays an important role in the life cycle of this emerging pathogen. Although T6SS2 was recently shown to play a
Daniel Tchelet +3 more
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The Versatile Type VI Secretion System [PDF]
Microbiology Spectrum, 2016 ABSTRACT Bacterial type VI secretion systems (T6SSs) function as contractile nanomachines to puncture target cells and deliver lethal effectors. In the 10 years since the discovery of the T6SS, much has been learned about the structure and function of this versatile protein secretion apparatus.
Christopher J, Alteri, Harry L T, Mobley
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Marker for type VI secretion system effectors [PDF]
Proceedings of the National Academy of Sciences, 2014 Significance The recently discovered type VI secretion system (T6SS) is used by Gram-negative bacteria to deliver effector proteins into both eukaryotic and prokaryotic neighboring cells to mediate virulence and competition, respectively. Even though several T6SS effector families have been described, many T6SSs are not associated with known ...
Dor, Salomon +7 more
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Causalities of war: The connection between type VI secretion system and microbiota [PDF]
, 2020 Cellular Microbiology published by John Wiley & Sons Ltd Microbiota niches have space and/or nutrient restrictions, which has led to the coevolution of cooperation, specialisation, and competition within the population.
Allsopp, Luke P. +3 more
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Structural biology of type VI secretion systems [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2012 Type VI secretion systems (T6SSs) are transenvelope complexes specialized in the transport of proteins or domains directly into target cells. These systems are versatile as they can target either eukaryotic host cells and therefore modulate the bacteria–host interaction and pathogenesis or bacterial cells and therefore facilitate access to a specific ...
Cascales, E., Cambillau, Christian
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Type VI secretion systems in plant‐associated bacteria [PDF]
Environmental Microbiology, 2017 Summary The type VI secretion system (T6SS) is a bacterial nanomachine used to inject effectors into prokaryotic or eukaryotic cells and is thus involved in both host manipulation and interbacterial competition. The T6SS is widespread among Gram‐negative bacteria, mostly within the Proteobacterium Phylum.
Patricia Bernal +2 more
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