Results 121 to 130 of about 22,420 (243)

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

Kojic acid-derived tyrosinase inhibitors: synthesis and bioactivity

Pharmaceutical and Biomedical Research, 2015
Tyrosinase is a key enzyme for melanin biosynthesis, catalyzing the oxidation of L-tyrosine to L-dopaquinone. The tyrosinase inhibition is an effective approach to control hyperpigmentation in human skin and enzymatic browning in fruits and vegetables ...
Seyedeh Mahdieh Hashemi, Saeed Emami
doaj  

Potent inhibition of human tyrosinase inhibitor by verproside from the whole plant of Pseudolysimachion rotundum var. subintegrum. [PDF]

J Enzyme Inhib Med Chem, 2023
Jung S, Woo SY, Park MH, Kim DY, Lee SU, Oh SR, Kim MO, Lee J, Ryu HW.   +8 more
europepmc   +1 more source

Pemanfaatan Ekstrak Khamir Phaffia Rhodozyma Sebagai Sumber Karotenoid Pada Penghambatan Tirosinase [PDF]

, 2017
Ekstrak khamir Phaffia rhodozyma mengandung senyawa karotenoid berupa astaxhantin yang memiliki aktivitas sebagai penghambat tirosinase. Senyawa ini dapat menghambat tirosinase dalam mekanisme pembentukan melanin.
Rahardhian, M. R. (Muhammad), Wulandari, W. (Wulandari)   +1 more
core  

Tyrosine-like condensed derivatives as tyrosinase inhibitors

Journal of Pharmacy and Pharmacology, 2012
AbstractObjectivesWe report the pharmacological evaluation of a new series of 3-aminocoumarins differently substituted with hydroxyl groups, which have been synthesized because they include in their structures the tyrosine fragment (tyrosine-like compounds), with the aim of discovering structural features necessary for tyrosinase inhibitory activity ...
Matos M. J, Santana L, Uriarte E, SERRA, SILVIA, Corda M, Fadda M. B, ERA, BENEDETTA, FAIS, ANTONELLA   +7 more
openaire   +2 more sources

Comprehensive Exploration of Three Pistachio Varieties: Antidiabetic, Anticholinergic, Antioxidant Properties, Phytochemical Profile by LC–MS/MS, and Molecular Docking

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Phytochemical profiles, biological activities, and molecular docking studies of pistachio varieties. ABSTRACT Pistachios (Pistacia vera L.) are a significant food that is added to many foods and also consumed as a snack. The kernel part is consumed very much.
Ebubekir İzol, Büşra Beltekin, Münire Turhan, Şirvan Karakoç, Adem Necip, Mustafa Abdullah Yılmaz, Gökhan Zengin, Oğuz Çakır   +7 more
wiley   +1 more source

Investigation of phenyllactic acid as a potent tyrosinase inhibitor produced by probiotics. [PDF]

Curr Res Food Sci, 2023
Shin M, Truong VL, Lee M, Kim D, Kim MS, Cho H, Jung YH, Yang J, Jeong WS, Kim Y.   +9 more
europepmc   +1 more source

Quercetin and Its Nano‐Based Formulations Against Skin Cancer: A Narrative Review

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Skin cancer is one of the most prevalent malignancies worldwide, characterized by the abnormal growth of skin cells and significant clinical challenges. Conventional treatments—including surgery, chemotherapy, and radiotherapy—often suffer from limitations such as adverse side effects, tumor resistance, and inadequate efficacy.
Mahtab Khanyabzadeh, Alireza Emamifar, Nikoo Emtiazi, Amir Nazari, Masoumeh Shekarriz, Amin Karami, Fateme Hashem Beik Mahallati, Rahineh Nomani Lafmejani, Atieh Dariush, Seyed Mohammad Mahdi Rohani, Elaheh Mohseni Vadeghani, Negin Khoshnood, Hamid Reza Ojaghi, Fatemeh Rezaei‐Tazangi, Reza Arefnezhad   +14 more
wiley   +1 more source

Synthesis and biological assessment of novel 4H-chromene-3-carbonitrile derivatives as tyrosinase inhibitors

BMC Chemistry
Excessive activity of the tyrosinase enzyme during melanogenesis results in hyperpigmentation in the skin. To address this issue, there is a need to develop effective tyrosinase inhibitors as a treatment for hyperpigmentation.
Mohammad Azimi, Zahra Najafi, Asrin Bahmani, Gholamabbas Chehardoli, Aida Iraji   +4 more
doaj   +1 more source

Hop Tannins as Multifunctional Tyrosinase Inhibitor: Structure Characterization, Inhibition Activity, and Mechanism. [PDF]

Antioxidants (Basel), 2022
Liu J, Chen Y, Zhang X, Zheng J, Hu W, Teng B.   +5 more
europepmc   +1 more source