Results 11 to 20 of about 677,076 (187)

Identification of Tyrosinase Inhibitors and Their Structure-Activity Relationships via Evolutionary Chemical Binding Similarity and Structure-Based Methods

open access: yesMolecules, 2021
Tyrosinase is an enzyme that plays a crucial role in the melanogenesis of humans and the browning of food products. Thus, tyrosinase inhibitors that are useful to the cosmetic and food industries are required.
Prasannavenkatesh Durai   +4 more
doaj   +3 more sources

Heterocyclic Compounds as Synthetic Tyrosinase Inhibitors: Recent Advances [PDF]

open access: yesInternational Journal of Molecular Sciences, 2023
Tyrosinase is a copper-containing enzyme which is widely distributed in nature (e.g., bacteria, mammals, fungi) and involved in two consecutive steps of melanin biosynthesis.
Serena Vittorio   +2 more
exaly   +4 more sources

The Guanidine Pseudoalkaloids 10-Methoxy-Leonurine and Leonurine Act as Competitive Inhibitors of Tyrosinase

open access: yesBiomolecules, 2020
Tyrosinase plays a key role in the production of melanin. A variety of industrial fields have shown interest in the development of tyrosinase inhibitors from plants.
Jang Hoon Kim   +2 more
doaj   +2 more sources

Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitors

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2017
Melanogenesis is a process to synthesize melanin, which is a primary responsible for the pigmentation of human skin, eye and hair. Although numerous enzymatic catalyzed and chemical reactions are involved in melanogenesis process, the enzymes such as ...
Thanigaimalai Pillaiyar   +2 more
doaj   +2 more sources

Phlorotannins Derived From the Brown Alga as Tyrosinase Inhibitors

open access: yesNatural Product Communications, 2021
Tyrosinase catalyzes hydroxylation of L-tyrosine and dehydrogenation of L-DOPA in the melanin biosynthesis pathway. Tyrosinase inhibitors have potential use as cosmetic whitening agents and for preventing seafood deterioration. In this report, tyrosinase
Hideyuki Kurihara, Kazuki Kujira
doaj   +2 more sources

Screening of Peruvian Medicinal Plants for Tyrosinase Inhibitory Properties: Identification of Tyrosinase Inhibitors in Hypericum laricifolium Juss

open access: yesMolecules, 2017
Tyrosinase inhibitors are of far-ranging importance in cosmetics, medicinal products, and food industries. Peru is a diverse country with a wide variety of plants that may contain excellent anti-tyrosinase inhibitors. In the present study, the tyrosinase
Yanymee Nimesia Guillen Quispe   +3 more
doaj   +2 more sources

Natural peptides and proteins: potent tyrosinase inhibitors [PDF]

open access: yesResearch Journal of Pharmacognosy, 2017
Background and objectives: Tyrosinase is a copper containing oxidase which is crucial for controlling the production of melanin in creatures such as bacteria, fungi, plants and mammals.
R. Hariri*, M. Saeedi, T. Akbarzadeh
doaj   +1 more source

Identification by shape-based virtual screening and evaluation of new tyrosinase inhibitors [PDF]

open access: yesPeerJ, 2018
Targeting tyrosinase is considered to be an effective way to control the production of melanin. Tyrosinase inhibitor is anticipated to provide new therapy to prevent skin pigmentation, melanoma and neurodegenerative diseases.
Qi Li   +7 more
doaj   +4 more sources

Functionality study of chalcone-hydroxypyridinone hybrids as tyrosinase inhibitors and influence on anti-tyrosinase activity

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
In an attempt to synthesise new tyrosinase inhibitors, we designed and synthesised a series of chalcone-hydroxypyridinone hybrids as potential tyrosinase inhibitors adopting strategic modifications of kojic acid.
L. Ravithej Singh   +6 more
doaj   +2 more sources

Combined Kinetic Studies and Computational Analysis on Kojic Acid Analogs as Tyrosinase Inhibitors

open access: yesMolecules, 2014
Tyrosinase is a key enzyme in melanin synthesis and widely distributed in plants and animals tissues. In mammals, this enzyme is related to pigment production, involved in wound healing, primary immune response and it can also contribute to ...
Carlyle Ribeiro Lima   +7 more
doaj   +2 more sources

Home - About - Disclaimer - Privacy