Results 11 to 20 of about 7,340,584 (263)

Ubiquitin-specific proteases (USPs) in leukemia: a systematic review [PDF]

BMC Cancer
Background Leukemia, a type of blood cell cancer, is categorized by the type of white blood cells affected (lymphocytes or myeloid cells) and disease progression (acute or chronic).
Alireza Zangooie, Shima Tavoosi, Mahan Arabhosseini, Aram Halimi, Helia Zangooie, Amir Hossein Baghsheikhi, Soheila Rahgozar, Mohammad Ahmadvand, Alireza Mosavi Jarrahi, Zahra Salehi   +9 more
doaj   +5 more sources

Ubiquitin-Specific Proteases (USPs) and Metabolic Disorders [PDF]

International Journal of Molecular Sciences, 2023
Ubiquitination and deubiquitination are reversible processes that modify the characteristics of target proteins, including stability, intracellular localization, and enzymatic activity. Ubiquitin-specific proteases (USPs) constitute the largest deubiquitinating enzyme family.
Hiroshi Kitamura
exaly   +7 more sources

Ubiquitin-specific proteases are differentially expressed throughout the Schistosoma mansoni life cycle [PDF]

Parasites & Vectors, 2015
Background The ubiquitination process can be reversed by deubiquitinating enzymes (DUBs). These proteases are involved in ubiquitin processing, in the recovery of modified ubiquitin trapped in inactive forms, and in the recycling of ubiquitin monomers ...
Roberta V. Pereira, Matheus de S Gomes, Roenick P. Olmo, Daniel M. Souza, Fernanda J. Cabral, Liana K. Jannotti-Passos, Elio H. Baba, Andressa B. P. Andreolli, Vanderlei Rodrigues, William Castro-Borges, Renata Guerra-Sá   +10 more
doaj   +3 more sources

Role of ubiquitin specific proteases in the immune microenvironment of prostate cancer: A new direction [PDF]

Frontiers in Oncology, 2022
Regulation of ubiquitination is associated with multiple processes of tumorigenesis and development, including regulation of the tumor immune microenvironment.
Jinhui Guo, Jinhui Guo, Jie Zhao, Litao Sun, Chen Yang   +4 more
doaj   +2 more sources

Correction: Correction: Regulation of Neuronal Morphogenesis and Positioning by Ubiquitin-Specific Proteases in the Cerebellum. [PDF]

PLoS ONE, 2015
Correction: Correction: Regulation of Neuronal Morphogenesis and Positioning by Ubiquitin-Specific Proteases in the ...
PLOS ONE Staff
doaj   +3 more sources

Ubiquitin-specific proteases in ovarian cancer: molecular mechanisms and therapeutic implications [PDF]

Journal of Ovarian Research
Ovarian cancer (OC) remains one of the most lethal gynecological malignancies, largely due to late-stage diagnosis, frequent recurrence, and the development of resistance to standard therapies.
Lu Deng, Yuzhao Jiang, Danning Wang, Jing Yu, Lingying Wu   +4 more
doaj   +2 more sources

Ubiquitin-specific proteases as key regulators in the malignant progression and therapy resistance of colorectal cancer: current insights and future perspectives [PDF]

Discover Oncology
As a member of the DUBs (deubiquitinating enzymes) family, USPs (ubiquitin-specific peptidases) play a crucial regulatory role in the occurrence and progression of various malignancies.
Junyan Li, Shifan Deng, Wei Yu, Qian Ye, Dongxing Liu, Zhiling Yi, Chuanjian Liu, Jixiang Huang, Jinghua Zhong, Xiangcai Wang   +9 more
doaj   +2 more sources

Gene Signature and Prognostic Value of Ubiquitin-Specific Proteases Members in Hepatocellular Carcinoma and Explored the Immunological Role of USP36

Frontiers in Bioscience, 2022
Background: Ubiquitination is one of the most common post-translational modifications in cells and dysregulation is closely associated with the development of cancer.
Leilei Liang, Weijie Sun, Yufeng Gao
exaly   +3 more sources

Molecular Mechanisms of the Ubiquitin-Specific Proteases (USPs) Family in Biliary Tract Cancer and Targeted Intervention Strategies [PDF]

Biomedicines
Biliary tract carcinoma (BTC) is a group of highly heterogeneous malignancies arising from the biliary epithelium. Anatomically, BTC is categorized into gallbladder cancer (GBC) and cholangiocarcinoma (CCA), with the latter further subdivided into ...
Qian Cheng, Delin Ma, Shengmin Zheng, Jialing Hao, Gang Wang, Yanbin Ni, Jiye Zhu   +6 more
doaj   +2 more sources

Role of ubiquitin-specific proteases in programmed cell death of breast cancer cells [PDF]

Genes and Diseases
Breast cancer (BC) is the most common malignant tumor and the leading cause of cancer-related deaths among women worldwide. Great progress has been recently achieved in controlling breast cancer; however, mortality from breast cancer remains a ...
Wen Yan, Shasha Xiang, Jianbo Feng, Xuyu Zu   +3 more
doaj   +2 more sources