Results 121 to 130 of about 11,747 (233)

Design, Synthesis and Structure—Activity Relationships of Phenylalanine-Containing Peptidomimetics as Novel HIV-1 Capsid Binders Based on Ugi Four-Component Reaction [PDF]

, 2022
Xiangkai Ji, Jing Li, Prem P. Sharma, Xiangyi Jiang, Brijesh Rathi, Zhen Gao, Lide Hu, Dongwei Kang, Erik De Clercq, Simon Cocklin, Chuanfeng Liu, Christophe Pannecouque, Alexej Dick, Xinyong Liu, Peng Zhan   +14 more
openalex   +1 more source

Studies on the Synthesis, Structure and Biological Activities of Novel Arylaminoformyl-containing 1-Cyano-1-cycloproane Carboxylic Acid Amides Based on Ugi Reaction [PDF]

, 2015
Yizhou Zhan, Baolei Wang, Liyuan Zhang, Yan Zhang, Xiao Zhang, Zhengming Li, Haibin Song   +6 more
openalex   +1 more source

Preparation of 4 '-spirocyclobutyl nucleoside analogues as novel and versatile adenosine scaffolds

, 2019
Despite the large variety of modified nucleosides that have been reported, the preparation of constrained 4 '-spirocyclic adenosine analogues has received very little attention.
De Vleeschouwer, Freija, Kong, Hanchu, Meerpoel, Lieven, Pande, Vineet, Sun, Weimei, Thuring, Jan Willem, Van Hecke, Kristof, Verhoeven, Jonas, Verniest, Guido, Vos, Ann, Wu, Tongfei   +10 more
core   +1 more source

The multicomponent approach to N-methyl peptides: total synthesis of antibacterial (–)-viridic acid and analogues

Beilstein Journal of Organic Chemistry, 2012
Two syntheses of natural viridic acid, an unusual triply N-methylated peptide with two anthranilate units, are presented. The first one is based on peptide-coupling strategies and affords the optically active natural product in 20% overall yield over six
Ricardo A. W. Neves Filho, Sebastian Stark, Bernhard Westermann, Ludger A. Wessjohann   +3 more
doaj   +1 more source

Effective microwave-assisted approach to 1,2,3-triazolobenzodiazepinones via tandem Ugi reaction/catalyst-free intramolecular azide-alkyne cycloaddition. [PDF]

Beilstein J Org Chem, 2021
Mazur MO, Zhelavskyi OS, Zviagin EM, Shishkina SV, Musatov VI, Kolosov MA, Shvets EH, Andryushchenko AY, Chebanov VA.   +8 more
europepmc   +1 more source

Ugi reaction in the synthesis of Janus dendrimers as nanocarriers of chlorambucil and ibuprofen

Results in Chemistry
The synthesis and characterization of Janus dendrimers conjugated with two drugs: chlorambucil and ibuprofen are reported. The dendrons by the Ugi reaction were obtained.
Israel Barajas-Mendoza, Teresa Ramírez-Ápan, Marcos Martínez-García   +2 more
doaj   +1 more source

New tricks of well-known aminoazoles in isocyanide-based multicomponent reactions and antibacterial activity of the compounds synthesized

Beilstein Journal of Organic Chemistry, 2017
The well-known aminoazoles, 3-amino-5-methylisoxazole and 5-amino-N-aryl-1H-pyrazole-4-carboxamides, were studied as an amine component in Ugi and Groebke–Blackburn–Bienaymé multicomponent reactions.
Maryna V. Murlykina, Maryna N. Kornet, Sergey M. Desenko, Svetlana V. Shishkina, Oleg V. Shishkin, Aleksander A. Brazhko, Vladimir I. Musatov, Erik V. Van der Eycken, Valentin A. Chebanov   +8 more
doaj   +1 more source

Tritylamine as an Ammonia Surrogate in the Ugi Reaction Provides Access to Unprecedented 5-Sulfamido Oxazoles Using Burgess-type Reagents. [PDF]

Org Lett, 2021
Bhela IP, Serafini M, Del Grosso E, Tron GC, Pirali T.   +4 more
europepmc   +1 more source

Raising the Diversity of Ugi Reactions Through Selective Alkylations and Allylations of Ugi Adducts [PDF]

, 2019
Alaa Zidan, Abeer M. El‐Naggar, Nour E. A. Abd El‐Sattar, Ali Kh. Khalil, Laurent El Kaïm   +4 more
openalex   +1 more source

Synthesis of bis-furyl-pyrrolo[3,4-b]pyridin-5-ones via Ugi–Zhu reaction and in vitro activity assays against human SARS-CoV-2 and in silico studies on its main proteins

, 2022
Ivette Morales‐Salazar, Flora P. Montes-Enríquez, Carlos E. Garduño-Albino, Miguel A. García‐Sánchez, Ilich A. Ibarra, Yareli Rojas-Aguirre, Montserrat Elemi García-Hernández, Rosa Elena Sarmiento‐Silva, Sofía Lizeth Alcaráz‐Estrada, Erik Díaz‐Cervantes, Eduardo González‐Zamora, Alejandro Islas‐Jácome   +11 more
openalex   +2 more sources