Human esophageal cancer stem-like cells escape the cytotoxicity of natural killer cells via down-regulation of ULBP-1 [PDF]
Background Cancer stem-like cells (CSCs) play an important role in initiation and progression of aggressive cancers, including esophageal cancer. Natural killer (NK) cells are key effector lymphocytes of innate immunity that directly attack a wide ...
Bo Tang +6 more
doaj +4 more sources
Tri-Stage Offline Telugu Character Recognition System Based on Fusion of HOG and ULBP
The domain of pattern recognition has experienced a notable upsurge in the prevalence of handwritten character recognition, which is a research area that has been widely recognized for decades.However, this task presents significant challenges ...
Chandrakala Mukku, Miriala Santhosh
exaly +4 more sources
Automatic melanoma detection using an optimized five-stream convolutional neural network [PDF]
Melanoma is among the deadliest forms of malignant skin cancer, with the number of cases increasing dramatically worldwide. Its early and accurate diagnosis is crucial for effective treatment. However, automatic melanoma detection has several significant
Vida Esmaeili +2 more
doaj +2 more sources
Cross-Dressing of Multiple Myeloma Cells Mediated by Extracellular Vesicles Conveying MIC and ULBP Ligands Promotes NK Cell Killing [PDF]
Natural Killer (NK) cells are innate cytotoxic lymphoid cells that play a crucial role in cancer immunosurveillance. NKG2D is an activating receptor that binds to MIC and ULBP molecules typically induced on damaged, transformed, or infected cells. The secretion of NKG2D ligands (NKG2DLs) through protease-mediated cleavage or in an extracellular vesicle
Alessandra Soriani +2 more
exaly +7 more sources
Discovery of crucial cytokines associated with deep vein thrombus formation by protein array analysis [PDF]
Background Expanding the number of biomarkers is imperative for studying the etiology and improving venous thromboembolism prediction. In this study, we aimed to identify promising biomarkers or targeted therapies to improve the detection accuracy of ...
Qitao Wang +6 more
doaj +2 more sources
Existing scanners produce paper images with different types of deformations such as noise, rotation and shear. These deformations affect the accuracy of the fingerprinting the document images, which entails utilizing advanced feature extraction operators.
Shihab Hamad Khaleefah +3 more
doaj +1 more source
Image Retrieval Method Based on Image Feature Fusion and Discrete Cosine Transform
This paper presents a new content-based image retrieval (CBIR) method based on image feature fusion. The deep features are extracted from object-centric and place-centric deep networks. The discrete cosine transform (DCT) solves the strong correlation of
DaYou Jiang, Jongweon Kim
doaj +1 more source
Dynamic shift from CD85j/ILT-2 to NKG2D NK receptor expression pattern on human decidual NK during the first trimester of pregnancy. [PDF]
During the first trimester of human pregnancy, Natural Killer (NK) cells of the maternal uterine mucosa (e.g. decidua) have a unique phenotype and are involved in crucial physiological processes during pregnancy.
Romain Marlin +11 more
doaj +1 more source
Natural killer (NK) cells play a vital role in xenotransplantation rejection. One approach to induce NK cell immune tolerance is to prevent the NK cell-mediated direct killing of porcine cells by targeting the interaction of the activating receptor NKG2D
Kevin J. Lopez +9 more
doaj +1 more source
Background Cell surface NKG2D ligands (NKG2DL) bind to the activating NKG2D receptor present on NK cells and subsets of T cells, thus playing a role in initiating an immune response.
de Kruijf Esther M +10 more
doaj +1 more source

