Results 61 to 70 of about 2,195 (166)

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Strategies for Monitoring Serum Protein Degradation With an Antibody Array‐Based Technology

Journal of Clinical Laboratory Analysis, Volume 40, Issue 5, March 2026.
This study analyzed the stability of 480 proteins in human serum samples collected from 10 healthy donors and incubated at room temperature for 0–48 h. Antibody array profiling revealed significant time‐dependent degradation of 201 proteins. Subsequent physicochemical and functional enrichment analyses demonstrated that the degraded proteins were ...
Yanlin Wang, Min Lang, Wei Huang, Siwei Zhu, Yingqing Mao, Shuhong Luo, Hua Dong, Ruo‐Pan Huang   +7 more
wiley   +1 more source

Antibody‐Targeted Artificial T Cell and Natural Killer Cell Derived Vesicles for Cancer Immunotherapy

Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
ABSTRACT T cell and NK92 cell‐derived extracellular vesicles or artificial cell‐derived vesicles (ACDVs) exhibit anti‐cancer effects through inherited cytotoxic proteins like perforin and granzyme or transmembrane receptors like FasL and TRAIL. The anti‐cancer potential of artificial T and NK vesicles has been improved by attaching targeting moieties ...
Brijesh Parlekar, David W. Livingstone, Ashley R. Sutherland, Andrés X. Medina, Wendy Bernhard, John DeCoteau, Tays Hernández, Clarence Ronald Geyer   +7 more
wiley   +1 more source

Structural basis for recognition of cellular and viral ligands by NK cell receptors

Frontiers in Immunology, 2014
Natural killer (NK) cells are key components of innate immune responses to tumors and viral infections. NK cell function is regulated by NK cell receptors that recognize both cellular and viral ligands, including MHC, MHC-like, and non-MHC molecules ...
Roy eMariuzza, Yili eLi
doaj   +1 more source

Feature Selection for Facial Emotion Recognition Using Cosine Similarity-Based Harmony Search Algorithm

Applied Sciences, 2020
Nowadays, researchers aim to enhance man-to-machine interactions by making advancements in several domains. Facial emotion recognition (FER) is one such domain in which researchers have made significant progresses. Features for FER can be extracted using
Soumyajit Saha, Manosij Ghosh, Soulib Ghosh, Shibaprasad Sen, Pawan Kumar Singh, Zong Woo Geem, Ram Sarkar   +6 more
doaj   +1 more source

Fifty Years of Natural Killer Cells: Milestones and Future Horizons

Scandinavian Journal of Immunology, Volume 103, Issue 2, February 2026.
To mark 50 years of NK cell research, a 2025 Karolinska symposium traced discoveries from spontaneous cytotoxicity and “missing self” recognition to receptor biology, cellular diversity, and translational advances, highlighting NK cells’ evolution into modern immunotherapy.
Andreas Lundqvist, Arnika K. Wagner, Benedict J. Chambers, Carin I. M. Dahlberg, Jonas Sundbäck, Angelica Cuapio, Evren Alici, Hans‐Gustaf Ljunggren   +7 more
wiley   +1 more source

Decoding Student Emotions: An Advanced CNN Approach for Behavior Analysis Application Using Uniform Local Binary Pattern

IEEE Access
In this paper, Facial Emotion detection model, built using Uniform Local Binary Pattern, is explained using an application i.e., Student behavior detection. Student engagement is a critical factor in effective teaching and learning.
Uppanapalli Lakshmi Sowjanya, R. Krithiga   +1 more
doaj   +1 more source

Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus.

PLoS Pathogens, 2016
The natural killer cell receptor NKG2D activates NK cells by engaging one of several ligands (NKG2DLs) belonging to either the MIC or ULBP families. Human cytomegalovirus (HCMV) UL16 and UL142 counteract this activation by retaining NKG2DLs and US18 and ...
Elizabeth R Sturgill, Daniel Malouli, Scott G Hansen, Benjamin J Burwitz, Seongkyung Seo, Christine L Schneider, Jennie L Womack, Marieke C Verweij, Abigail B Ventura, Amruta Bhusari, Krystal M Jeffries, Alfred W Legasse, Michael K Axthelm, Amy W Hudson, Jonah B Sacha, Louis J Picker, Klaus Früh   +16 more
doaj   +1 more source

From Neuron‐Centric to Glia‐Centric: How Aging Glial Networks Drive Neurodegenerative Disease

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
During aging, progressive alterations in glial networks reshape intercellular communication within the central nervous system. In the young brain, astrocytes and microglia actively regulate metabolic, immune, and synaptic processes that sustain neural circuit stability.
Lívia de Sá Hayashide, Bruna Pessoa, Gustavo Dias, Bruno Pontes, Rafael Serafim Pinto, Luan Pereira Diniz   +5 more
wiley   +1 more source

Case Reports of Alopecia Areata Associated With Apical Periodontitis

Case Reports in Dentistry, Volume 2026, Issue 1, 2026.
Apical periodontitis is an inflammatory response of periradicular tissues caused by microbial infection within the root canal system. Alopecia areata (AA) is a T‐cell mediated, autoimmune condition affecting hair follicles causing nonscarring hair loss, clinically characterised by small patches of baldness on the scalp and/or around the body.
Aleksandra Zuza, Aylin Baysan, Katarina Grcic, Ivona Bago, Hannah Bennett, Flavio Pisani, Shalini Kanagasingam, Priya Gusain   +7 more
wiley   +1 more source