Results 21 to 30 of about 2,160 (157)
BackgroundThe poor clinical accuracy to predict the survival of colon cancer patients is associated with a high incidence rate and a poor 3-year survival rate.
Zhen Ye +4 more
doaj +1 more source
A prognostic model for cervical cancer based on ferroptosis-related genes
BackgroundFerroptosis is widely involved in the occurrence and development of various cancers, but a specific mechanism involving ferroptosis in cervical cancer is still unclear.MethodsBased on the expressions of ferroptosis-related genes, a prognostic ...
Huijun Du +12 more
doaj +1 more source
ULBP2 is differentially expressed in central nervous system metastasis in human breast cancer.
Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with ...
Shahan Mamoor
core +1 more source
Structure of the HCMV UL16-MICB complex elucidates select binding of a viral immunoevasin to diverse NKG2D ligands. [PDF]
The activating immunoreceptor NKG2D promotes elimination of infected or malignant cells by cytotoxic lymphocytes through engagement of stress-induced MHC class I-related ligands.
Steffen Müller +3 more
doaj +1 more source
Expression of the stress-induced ligands MICA, MICB and ULBP 1–6 are up-regulated as a cellular response to DNA damage, excessive proliferation or viral infection; thereby, they enable recognition and annihilation by immune cells that express the ...
Dominik Schmiedel +5 more
doaj +1 more source
The Pneumoviridae family includes human metapneumovirus (HMPV) and human orthopneumovirus, which is also known as a respiratory syncytial virus (HRSV). These are large enveloped, negative single-strand RNA viruses.
Mohammad Diab +4 more
doaj +1 more source
Modulation of the antitumor immune response through the engagement of NKG2D receptors with their ligands (L) on targets represents a promising therapeutic approach against cancer.
Xiaosong Wu +4 more
doaj +1 more source
The outcome of infection is dependent on the ability of viruses to manipulate the infected cell to evade immunity, and the ability of the immune response to overcome this evasion.
Ceri Alan Fielding +20 more
doaj +1 more source
NK group 2, member D (NKG2D) is one of the most critical activating receptors expressed by natural killer (NK) cells. There is growing evidence that acute myeloid leukemia (AML) cells may evade NK cell-mediated cell lysis by expressing low or no ligands ...
Meng Liu +12 more
doaj +1 more source
ULBP2-TB40 infected cells have lower MHC class I surface expression than TB40 infected cells.
(A,B) Representative plots showing HLA class I expression using pan-HLA-A,B,C antibody (HLA I) or HLA-A02:01 antibody labeling of infected (IE1/2+) DC.
Mijo Golemac (721297) +10 more
core +1 more source

