Results 81 to 90 of about 2,160 (157)
, 2014 Supplemental Figure 2. (A) Gating strategy for NKG2D expression on NK cells in FNA and PBMCs from an ATC patient. Lymphocytes are gated according to size (forward scatter FSC) and granularity (side scatter SSC), viability (7AAD- cells), NK cell phenotype
C Christofer Juhlin (14996856) +13 more
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CD20-Specific Immunoligands Engaging NKG2D Enhance γδ T Cell-Mediated Lysis of Lymphoma Cells [PDF]
, 2017 Human γδ T cells are innate-like T cells which are able to kill a broad range of tumour cells and thus may have potential for cancer immunotherapy. The activating receptor natural killer group 2 member D (NKG2D) plays a key role in regulating immune ...
Parren, P. W.H.I. +23 more
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, 2012 Malignant cells express ligands for the natural killer cell immunoreceptor NKG2D, which sensitizes to early recognition and elimination by cytotoxic lymphocytes and provides an innate barrier against tumor development.
Sonali Pechlivanis +7 more
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Apoptotic compound treatment also leads to loss of cell surface ULBP2.
, 2014 (A) Loss of cell surface ULBP2 expression in apoptotic compounds-treated cells. Jurkat cells (upper panels) were treated with 4 µg/ml Actinomycin D (ActD), 4 µM CPT, 25 µM ETO or DMSO for 4 hours in serum-free RPMI 1640 medium, and then were collected ...
Peter D. Sun (206280) +1 more
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Expanded network analysis using STRING in solid cancer patients.
, 2023 The panel shows the expanded network for genes found significantly up-regulated (Log FC greater and equal to 0.5) for solid cancer patients. In bold those genes (SSX1, MAGEC2 and ULBP2) found shared across solid and blood patients. (TIF)
Daniele Generali (426339) +20 more
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Spread of the ULBP2-expressing HCMV strain is strongly controlled by NK cells.
, 2016 (A) The ULBP2-TB40 strain was generated by insertion of a ULBP2 expression cassette (driven by the mouse CMV major immediate-early promoter (mMIEP)), replacing ORF UL16 in the BAC-cloned TB40 genome that lacks also the US1 to US6 region.
Mijo Golemac (721297) +10 more
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Expanded network analysis using STRING in blood cancer patients.
, 2023 The panel reports the expanded network for genes found significantly up-regulated (Log FC greater and equal to 0.5) for blood patients. In bold those genes (SSX1, MAGEC2 and ULBP2) found shared across solid and blood patients. (TIF)
Daniele Generali (426339) +20 more
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HCMV-specific CTL activated by ULBP2-expressing infected DC strongly downregulate NKG2D.
, 2016 (A) Representative staining of pp65-CTL for IFNγ, TNFα and CD107a after co-culturing with infected DC derived from one donor. Graphs represent compiled data for 3 donors as percentages of IFNγ, TNFα and CD107a positive pp65-CTL after co-culturing with ...
Mijo Golemac (721297) +10 more
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Validation of quantitative proteomics result using immunoblots.
, 2019 (A) Western blotting analysis of proteins with increased (Crk, SerpinB3, Cystatin-M), decreased (ULBP2), and unchanged secretion (Follistatin) in conditioned media (CM) and cell extract (CE) samples from PC3/nKR cells as compared with those from PC3 ...
Oh Kwang Kwon (1471246) +11 more
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RAET1G1 protein is poorly expressed at the cell surface.
, 2013 (A) Stable cell lines expressing N-terminal GFP fusion proteins of ULBP2, and RAET1G1, were created in HT1080 cells. The transfectants expressed equivalent levels of transgene, as evident by total GFP fluorescence (open histogram), plotted versus ...
Sophie Caillat-Zucman (188152) +11 more
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