Results 91 to 100 of about 16,335 (189)
A circular uncoating mechanism [PDF]
The Journal of Cell Biology, 2003 ![Graphic][1] High curvature on smaller vesicles speeds hydrolysis of Arf1-GTP. Antonny/MacmillanIn retrospect it seems obvious. If you need to uncoat a vesicle only after the vesicle has formed, use the spherical shape of the vesicle as a trigger for uncoating. Now, Joelle Bigay,
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Cell Reports, 2017 Although microtubule motors mediate intracellular virus transport, the underlying interactions and control mechanisms remain poorly defined. This is particularly true for HIV-1 cores, which undergo complex, interconnected processes of cytosolic transport,
Viacheslav Malikov, Mojgan H. Naghavi
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A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71
, 2012 Enterovirus 71 (EV71) is a major agent of hand, foot and mouth disease in children that can cause severe central nervous system disease and death. No vaccine or antiviral therapy is available.
Zihe Rao +18 more
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Serum albumin inhibits echovirus 7 uncoating
, 1999 Echoviruses induce a wide spectrum of diseases in man, the most severe being meningitis. In neonates, however, a severe systemic infection can be observed, leading to death.
Almond, JW +3 more
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Identification of Capsid Mutations That Alter the Rate of HIV-1 Uncoating in Infected Cells
, 2014 After viral fusion with the cell membrane, the conical capsid of HIV-1 disassembles by a process called uncoating. We recently utilized the cyclosporine (CsA) washout assay, in which TRIM-CypA-mediated restriction of viral replication is used to detect ...
Hope, Thomas J. +3 more
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Complementary assays reveal a relationship between HIV-1 uncoating and reverse transcription
, 2011 During the early stages of HIV-1 replication the conical capsid composed of p24 CA protein dissociates from the rest of the cytoplasmic viral complex by a process called uncoating.
Perez, Omar +5 more
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eLife, 2014 Mutations in the inositol 5-phosphatase OCRL cause Lowe syndrome and Dent's disease. Although OCRL, a direct clathrin interactor, is recruited to late-stage clathrin-coated pits, clinical manifestations have been primarily attributed to intracellular ...
Ramiro Nández +9 more
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Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells.
PLoS Pathogens, 2016 Disassembly of the cone-shaped HIV-1 capsid in target cells is a prerequisite for establishing a life-long infection. This step in HIV-1 entry, referred to as uncoating, is critical yet poorly understood.
Ashwanth C Francis +4 more
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HIV-1 capsid uncoating initiates after the first strand transfer of reverse transcription
, 2020 BACKGROUND: Correct disassembly of the HIV-1 capsid shell, called uncoating, is increasingly recognised as central for multiple steps during retroviral replication.
Philip J Murray (9127091) +2 more
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TNOA Journal of Ophthalmic Science and Research, 2022 Smital Mahadeorao Metange +1 more
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