Results 81 to 90 of about 15,312 (202)

Model for ASFV internalization and uncoating.

open access: yes, 2016
ASFV enters swine macrophages by clathrin-mediated endocytosis (left) and constitutive macropinocytosis (right). After the uptake, incoming particles are transported from early endosomes or macropinosomes to late endosomes, where they undergo the ...
Germán Andrés (2626936)   +3 more
core   +1 more source

Uncoating of Poliovirus by Isolated Plasma Membranes [PDF]

open access: yesJournal of Virology, 1970
Poliovirus type I LSc strain labeled with 14 C-uridine was adsorbed onto isolated plasma membranes and incubated with them. When membranes from Hep-2 or Vero cells were used, 22% of the label was converted to a trichloroacetic acid-soluble form, when trypsin or ribonuclease was added, the fraction
V F, Chan, F L, Black
openaire   +2 more sources

Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 7, Page 1578-1601, April 2026.
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy   +16 more
wiley   +1 more source

Endosomal ions and serum promote enterovirus uncoating

open access: yes, 2020
Enterovirusten B ryhmään kuuluva Echovirus 1 on RNA-virus, jonka tiedetään infektoivan soluja ei-happamien endosomien välityksellä ja kerääntyvän neutraaleihin multivesikulaarisiin kappaleisiin.
Haapakoski, Marjo
core  

DNA confinement drives uncoating of the HIV Virus

open access: yes, 2014
The enzyme reverse transcriptase converts single-stranded RNA molecules into double-stranded DNA molecules inside mature HIV viral capsids. We present a model for the uncoating of the HIV virus where the capsid uncoating process is driven by the ...
R. Bruinsma, I. Rouzina
core   +1 more source

Tobamoviruses CP Proteins Hijack Light‐Induced Protein (NbLIP1) to Promote Viral Replication by Facilitating VRO Formation

open access: yesPlant Biotechnology Journal, Volume 24, Issue 4, Page 2419-2438, April 2026.
ABSTRACT Tobamoviruses establish viral replication organelles (VROs) on the host endoplasmic reticulum (ER) for their replication, a process demanding substantial different types of lipids. However, how viruses efficiently transfer these lipids from other compartments like chloroplasts remains incompletely understood.
Haoyu Chen   +10 more
wiley   +1 more source

The Host Cell Metabolite Inositol Hexakisphosphate Promotes Efficient Endogenous HIV-1 Reverse Transcription by Stabilizing the Viral Capsid

open access: yesmBio, 2020
A defining activity of retroviruses is reverse transcription, the process by which the viral genomic RNA is converted into the double-stranded DNA required for virus replication.
Jordan Jennings   +4 more
doaj   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 3, Page 547-561, March 2026.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan   +22 more
wiley   +1 more source

Structure, Function and Dynamics in Adenovirus Maturation

open access: yesViruses, 2014
Here we review the current knowledge on maturation of adenovirus, a non-enveloped icosahedral eukaryotic virus. The adenovirus dsDNA genome fills the capsid in complex with a large amount of histone-like viral proteins, forming the core.
Walter F. Mangel, Carmen San Martín
doaj   +1 more source

Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection

open access: yesAdvanced Genetics, Volume 7, Issue 1, March 2026.
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man   +7 more
wiley   +1 more source

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