Results 81 to 90 of about 16,335 (189)
Liver International, Volume 46, Issue 10, October 2026.ABSTRACT Background Primary Biliary Cholangitis (PBC) is an autoimmune cholangiopathy with polygenic architecture and unknown aetiology. Evidence links Neanderthal‐derived genetic variants to autoimmune conditions; however, their contribution to PBC susceptibility remains unexplored.
Alessio Gerussi +269 more
wiley +1 more source
Model for ASFV internalization and uncoating.
, 2016 ASFV enters swine macrophages by clathrin-mediated endocytosis (left) and constitutive macropinocytosis (right). After the uptake, incoming particles are transported from early endosomes or macropinosomes to late endosomes, where they undergo the ...
Germán Andrés (2626936) +3 more
core +1 more source
mBio, 2020 A defining activity of retroviruses is reverse transcription, the process by which the viral genomic RNA is converted into the double-stranded DNA required for virus replication.
Jordan Jennings +4 more
doaj +1 more source
Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies
Advanced Science, Volume 13, Issue 50, 7 September 2026.Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi +5 more
wiley +1 more source
, 2008 Porcine reproductive and respiratory syndrome virus (PRRSV) replicates in differentiated macrophages. In macrophages, heparan sulphate glycosaminoglycans mediate the initial PRRSV attachment and the receptor sialoadhesin mediates both PRRSV attachment ...
Delputte, Peter +5 more
core +1 more source
Differential modulation of HIV-1 capsid uncoating kinetics revealed by a novel single-particle uncoating assay [PDF]
, 2019 The HIV-1 capsid has been recognised as an attractive antiviral target due to its central role during infection. It acts as a shield to protect the viral genome, facilitates reverse transcription, engages with the nuclear pore complex, and directs ...
Marquez Badilla, Chantal
core +1 more source
Neuronal Apoptotic Bodies Facilitate Japanese Encephalitis Virus Infection and Pathogenicity
Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.ABSTRACT Japanese encephalitis (JE) caused by Japanese encephalitis virus (JEV) infection remains one of the major types of viral encephalitis. The mechanisms underlying JEV infection and pathogenesis have not been fully elucidated, resulting in the absence of specific therapies for JE. Neuronal apoptosis is a well‐established outcome of JEV infection;
Chuan Zeng +9 more
wiley +1 more source
Viruses, 2015 Viruses that specifically replicate in tumor over normal cells offer promising cancer therapies. Oncolytic viruses (OV) not only kill the tumor cells directly; they also promote anti-tumor immunotherapeutic responses.
Adil Mohamed +2 more
doaj +1 more source
mBio, 2018 Once HIV-1 enters a cell, the viral core is uncoated by a poorly understood mechanism and the HIV-1 genomic RNA is reverse transcribed into DNA. Host cell factors are essential for these processes, although very few reverse transcription complex binding ...
Daniel J. Rawle +5 more
doaj +1 more source
Host cell factors regulate HIV-1 uncoating.
, 2018 The HIV-1 virion, which contains the CypA, ERK2, and eEF1A host proteins that regulate uncoating, binds and fuses with the host cell membrane, and the core is released into the cytoplasm.
David Harrich (37749) +1 more
core +1 more source