Results 101 to 110 of about 15,312 (202)

HIV-1 capsid uncoating initiates after the first strand transfer of reverse transcription

open access: yes, 2020
BACKGROUND: Correct disassembly of the HIV-1 capsid shell, called uncoating, is increasingly recognised as central for multiple steps during retroviral replication.
Philip J Murray (9127091)   +2 more
core  

A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells

open access: yeseLife, 2014
Mutations in the inositol 5-phosphatase OCRL cause Lowe syndrome and Dent's disease. Although OCRL, a direct clathrin interactor, is recruited to late-stage clathrin-coated pits, clinical manifestations have been primarily attributed to intracellular ...
Ramiro Nández   +9 more
doaj   +1 more source

Uncoating of Clathrin-Coated Vesicles in Presynaptic Terminals Roles for Hsc70 and Auxilin

open access: yes, 2001
We have examined the roles of Hsc70 and auxilin in the uncoating of clathrin-coated vesicles (CCVs) during neuronal endocytosis. We identified two peptides that inhibit the ability of Hsc70 and auxilin to uncoat CCVs in vitro.
Morgan, Jennifer R.   +4 more
core   +1 more source

Mechanisms of Entry and Endosomal Pathway of African Swine Fever Virus

open access: yesVaccines, 2017
African Swine Fever Virus (ASFV) causes a serious swine disease that is endemic in Africa and Sardinia and presently spreading in Russia and neighboring countries, including Poland and recently, the Czech Republic.
Elena G. Sánchez   +2 more
doaj   +1 more source

Involvement of proteases in porcine reproductive and respiratory syndrome virus uncoating upon internalization in primary macrophages

open access: yes, 2008
Porcine reproductive and respiratory syndrome virus (PRRSV) replicates in differentiated macrophages. In macrophages, heparan sulphate glycosaminoglycans mediate the initial PRRSV attachment and the receptor sialoadhesin mediates both PRRSV attachment ...
Delputte, Peter   +5 more
core   +1 more source

Dengue Virus Genome Uncoating Requires Ubiquitination [PDF]

open access: yes, 2016
The process of genome release or uncoating after viral entry is one of the least-studied steps in the flavivirus life cycle. Flaviviruses are mainly arthropod-borne viruses, including emerging and reemerging pathogens such as dengue, Zika, and West Nile ...
Leopoldo G. Gebhard   +16 more
core   +1 more source

Unraveling the motions behind Enterovirus 71 uncoating

open access: yes, 2018
Enterovirus 71 can be a severe pathogen in small children and immunocompromised adults. Virus uncoating is a critical step in the infection of the host cell; however, the mechanisms that control this process remain poorly understood.
Ross, Caroline Jane   +10 more
core   +1 more source

Serum albumin inhibits echovirus 7 uncoating

open access: yes, 1999
Echoviruses induce a wide spectrum of diseases in man, the most severe being meningitis. In neonates, however, a severe systemic infection can be observed, leading to death.
Jeffrey W. Almond   +7 more
core  

Picornavirus uncoating intermediate captured in atomic detail

open access: yes, 2013
It remains largely mysterious how the genomes of non-enveloped eukaryotic viruses are transferred across a membrane into the host cell. Picornaviruses are simple models for such viruses, and initiate this uncoating process through particle expansion ...
Wang, X   +21 more
core   +1 more source

Coats uncoated!

open access: yesTNOA Journal of Ophthalmic Science and Research, 2022
Smital Mahadeorao Metange   +1 more
openaire   +2 more sources

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