Results 101 to 110 of about 16,335 (189)

The Host Proteins Transportin SR2/TNPO3 and Cyclophilin a Exert Opposing Effects on HIV-1 Uncoating

, 2019
Following entry of the HIV-1 core into target cells, productive infection depends on the proper disassembly of the viral capsid (uncoating). Although much is known regarding HIV-1 entry, the actions of host cell proteins that HIV-1 utilizes during early ...
Shi, Jiong, Shotwell, Matthew S., Engelman, Alan, Shah, Vaibhav B., Oztop, Ilker, Krishnan, Lavanya, Aiken, Christopher, Hout, David R., Ahn, Jinwoo   +8 more
core   +1 more source

Identification of Novel Determinants of HIV-1 Uncoating in the Capsid Protein

, 2009
Uncoating of the viral core following penetration into the target cell represents a fundamentally obscure step in the HIV-1 life cycle. Our laboratory has previously reported that mutations in the CA protein that positively and negatively alter the ...
Yang, Ruifeng
core  

Nsp2 replicase-mediated viral uncoating in porcine alveolar macrophages contributes to the attenuation of PRRSV-2 live attenuated vaccine

Journal of Virology
Type 2 porcine reproductive and respiratory syndrome virus (PRRSV-2) poses a major threat to global swine production. While live attenuated vaccines (LAVs) remain the most effective countermeasure, the molecular mechanisms underlying PRRSV-2 attenuation ...
Yuan-Zhe Bai, Hu Xu, Yong-Gang Liu, Yue Sun, Shi-Jia Xu, Meng-Xin Wang, Qian Wang, Zhi-Jun Tian, Chao-Liang Leng, Gang Wang, Tong-Qing An, Xue-Hui Cai, Hong-Liang Zhang, Yan-Dong Tang   +13 more
doaj   +1 more source

Adducin‐1 Facilitates Influenza Virus Endosomal Trafficking and Uncoating by Regulating Branched Actin Dynamics and Myosin IIB Activity

Advanced Science
Actin‐ and microtubule‐based transport systems are essential for the trafficking of endocytic viruses and cargoes. Microtubules facilitate long‐distance transport; however, the precise role of actin dynamics and its regulators during virus entry ...
Meijun Jiang, Jiahui Zou, Yaoming Jin, Chenjun Jiang, Shaoyu Tu, Tong Chen, Jinli Guo, Yanqing Cheng, Meilin Jin, Huanchun Chen, Hongbo Zhou   +10 more
doaj   +1 more source

Endosomal ions and serum promote enterovirus uncoating

, 2020
Enterovirusten B ryhmään kuuluva Echovirus 1 on RNA-virus, jonka tiedetään infektoivan soluja ei-happamien endosomien välityksellä ja kerääntyvän neutraaleihin multivesikulaarisiin kappaleisiin.
Haapakoski, Marjo
core  

Mechanism of HIV-1 capsid rupture and uncoating by reverse transcription. [PDF]

Proc Natl Acad Sci U S A
Ghosh K, Gupta M, Voth GA.
europepmc   +1 more source

The multi-pronged entry of African swine fever virus: from host factors to therapeutic targets. [PDF]

J Virol
Li J, Liu C, Huang W, Wang Y, Huang L, Weng C.   +5 more
europepmc   +1 more source

Reframing clathrin-mediated viral entry: evidence standards, context dependence and host-directed vulnerabilities. [PDF]

Front Cell Infect Microbiol
Wang Q, Xu L, Sun Y, Xia Y, Yue J.
europepmc   +1 more source

Arp2/3 complex-dependent actin remodeling is required for efficient RSV uncoating in A549 cells. [PDF]

J Virol
Xie E, Schubert M, Reeb J, Seligmann B, Schaks M, Müsken M, Steffen A, Stradal TEB, Haid S, Rottner K, Sieben C.   +10 more
europepmc   +1 more source

TRIM62 facilitates influenza A virus entry by regulating WASH-dependent endosomal trafficking. [PDF]

EMBO Rep
Gupta K, Pal S, Tyagi A, Bajaj R, Pathak T, Kaur G, Sharma D, Banerjee I.   +7 more
europepmc   +1 more source