Results 11 to 20 of about 16,335 (189)
Revisiting HIV-1 uncoating [PDF]
Retrovirology, 2010 HIV uncoating is defined as the loss of viral capsid that occurs within the cytoplasm of infected cells before entry of the viral genome into the nucleus.
Arhel Nathalie
doaj +6 more sources
EPS8 Facilitates Uncoating of Influenza A Virus [PDF]
Cell Reports, 2019 Summary: All viruses balance interactions between cellular machinery co-opted to support replication and host factors deployed to halt the infection. We use gene correlation analysis to perform an unbiased screen for host factors involved in influenza A ...
Gloria P Larson +2 more
exaly +5 more sources
Mechanisms of virus uncoating [PDF]
Trends in Microbiology, 1994 In a virus particle, the genome is highly condensed and protected by proteins and membrane bilayers. Before it can be replicated in a new host cell, uncoating must take place.
Greber, U F, Singh, I, Helenius, A
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Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis [PDF]
eLife, 2018 Uncoating of the metastable HIV-1 capsid is a tightly regulated disassembly process required for release of the viral cDNA prior to nuclear import. To understand the intrinsic capsid disassembly pathway and how it can be modulated, we have developed a ...
Chantal L Márquez +10 more
doaj +3 more sources
The uncoating of EV71 in mature late endosomes requires CD-M6PR [PDF]
Biology Open, 2022 Enterovirus 71 (EV71) is one of the causative agents of hand-foot-and-mouth disease, which in some circumstances could lead to severe neurological diseases.
Seii Ohka +10 more
doaj +4 more sources
Uncoating of non-enveloped viruses [PDF]
Current Opinion in Virology, 2013 Non-enveloped viruses enclose their genome in capsids built of repetitive polypeptides interlinked with cementing proteins, divalent cations or disulphides. Interactions are broken in a stepwise manner during entry into cells leading to genome uncoating.
Maarit Suomalainen +5 more
core +6 more sources
Fluorescent image analysis of HIV-1 and HIV-2 uncoating kinetics in the presence of old world monkey TRIM5α. [PDF]
PLoS ONE, 2015 Uncoating of Human Immunodeficiency Virus type 1 (HIV-1) and type 2 (HIV-2) conical cores is an important early step for establishment of infection.
Eri Takeda +5 more
doaj +2 more sources
Influenza A virus uncoating [PDF]
, 2020 Influenza A virus (IAV) is an enveloped virus of the Orthomyxoviridae with a negative-sense single-stranded RNA genome. During virus cell entry, viral and cellular cues are delivered in a stepwise manner within two distinct cellular compartments—the ...
Yamauchi, Yohei, Yohei Yamauchi
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Membrane Uncoating of Intact Enveloped Viruses [PDF]
Journal of Virology, 2010 Experiments in the 1960s showed that Sendai virus, a paramyxovirus, fused its membrane with the host plasma membrane. After membrane fusion, the virus spontaneously “uncoated” with diffusion of the viral membrane proteins into the host plasma membrane ...
Anne M. Haywood
core +3 more sources
Clathrin uncoating: Auxilin comes to life [PDF]
Current Biology, 2001 The DnaJ protein auxilin has been extensively studied in vitro as a cofactor for uncoating clathrin-coated vesicles by the chaperone Hsc70. Recent studies provide the first evidence that auxilin plays this role in vivo, and work on a new mammalian ...
Sandra K Lemmon, Lemmon, Sandra K
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