Results 31 to 40 of about 15,312 (202)
Structure and Uncoating of Immature Adenovirus [PDF]
Journal of Molecular Biology, 2009 Maturation via proteolytic processing is a common trait in the viral world and is often accompanied by large conformational changes and rearrangements in the capsid. The adenovirus protease has been shown to play a dual role in the viral infectious cycle: (a) in maturation, as viral assembly starts with precursors to several of the structural proteins ...
Pérez-Berná, Ana J. +8 more
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Frontiers in Microbiology, 2020 Thermal shift assays measure the stability of macromolecules and macromolecular assemblies as a function of temperature. The Particle Stability Thermal Release Assay (PaSTRy) of picornaviruses is based on probes becoming strongly fluorescent upon binding
Antonio Real-Hohn +4 more
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Structural characterization of Ebola virus uncoating [PDF]
, 2023 Viruses initiate infection of host cells by entering through a variety of different pathways. Their entry is concluded by the release of the viral genome into the cytoplasm, where the cellular machinery gets repurposed for virus replication. Prerequisite
Winter, Sophie Luise
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Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles.
PLoS Pathogens, 2022 In infectious HIV-1 particles, the capsid protein (CA) forms a cone-shaped shell called the capsid, which encases the viral ribonucleoprotein complex (vRNP).
Ashwanth C Francis +7 more
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PLoS Pathogens, 2022 Nucleoli are membrane-less structures located within the nucleus and are known to be involved in many cellular functions, including stress response and cell cycle regulation. Besides, many viruses can employ the nucleolus or nucleolar proteins to promote
Sereina O Sutter +8 more
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Uncoating of Clathrin-Coated Vesicles by Uncoating ATPase from Developing Peas [PDF]
Plant Physiology, 1993 A cytosolic ATPase (an enzyme that dissociates clathrin from clathrin-coated vesicles in the presence of ATP) was isolated from developing pea (Pisum sativum L.) cotyledons using chromatography on ATP-agarose. After chromatography on phenyl Sepharose, the fraction with uncoating activity was enriched in a doublet of 70-kD peptides.
T, Kirsch, L, Beevers
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Proceedings, 2020 Flaviviruses are enveloped, arthropod-borne, positive-strand RNA viruses that cause significant human disease. While the basic mechanisms of flavivirus entry and fusion are understood, little is known about the postfusion events that precede RNA ...
Shuo Zhang +8 more
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Cells, 2022 Effective airborne transmission of coronaviruses via liquid microdroplets requires a virion structure that must withstand harsh environmental conditions.
Miguel Cantero +4 more
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eLife, 2021 HIV-1 replication commences inside the cone-shaped viral capsid, but timing, localization, and mechanism of uncoating are under debate. We adapted a strategy to visualize individual reverse-transcribed HIV-1 cDNA molecules and their association with ...
Thorsten G Müller +9 more
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Uncoating of influenza virus in endosomes [PDF]
Journal of Virology, 1984 The intracellular uncoating site of influenza virus was studied by measuring the fluorescence intensity of probes conjugated to the virus or the isolated hemagglutinin and also by assaying virus replication under various incubation conditions. Acidification of the viral environment was monitored by the decrease in the fluorescence intensity of ...
A, Yoshimura, S, Ohnishi
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