Results 31 to 40 of about 11,654 (172)
Dissection of GTPase activating proteins reveals functional asymmetry in the COPI coat of budding yeast. [PDF]
, 2019 The Arf GTPase controls formation of the COPI vesicle coat. Recent structural models of COPI revealed the positioning of two Arf1 molecules in contrasting molecular environments.
Arakel, E. +5 more
core +1 more source
Atomic Resolution Structure of the Oncolytic Parvovirus LuIII by Electron Microscopy and 3D Image Reconstruction. [PDF]
, 2017 LuIII, a protoparvovirus pathogenic to rodents, replicates in human mitotic cells, making it applicable for use to kill cancer cells. This virus group includes H-1 parvovirus (H-1PV) and minute virus of mice (MVM).
Agbandje-McKenna, Mavis +13 more
core +6 more sources
Real-time Fluorescence Measurement of Enterovirus Uncoating
Bio-Protocol, 2020 Viruses need to open, i.e., uncoat, in order to release their genomes for efficient replication and translation. Especially for non-enveloped viruses, such as enteroviruses, the cues leading to uncoating are less well known.
Visa Ruokolainen +2 more
doaj +1 more source
eLife, 2021 HIV-1 replication commences inside the cone-shaped viral capsid, but timing, localization, and mechanism of uncoating are under debate. We adapted a strategy to visualize individual reverse-transcribed HIV-1 cDNA molecules and their association with ...
Thorsten G Müller +9 more
doaj +1 more source
Uncoating of non-enveloped viruses [PDF]
Current Opinion in Virology, 2013 Non-enveloped viruses enclose their genome in capsids built of repetitive polypeptides interlinked with cementing proteins, divalent cations or disulphides. Interactions are broken in a stepwise manner during entry into cells leading to genome uncoating. Receptor or proteases induce conformational changes in case of rhinovirus, poliovirus or adenovirus,
Suomalainen Maarit, Greber Urs F
openaire +3 more sources
HIV-1 Capsid Core: A Bullet to the Heart of the Target Cell
Frontiers in Microbiology, 2021 The first step of the intracellular phase of retroviral infection is the release of the viral capsid core in the cytoplasm. This structure contains the viral genetic material that will be reverse transcribed and integrated into the genome of infected ...
Elenia Toccafondi +2 more
doaj +1 more source
A Spotlight on Viruses—Application of Click Chemistry to Visualize Virus-Cell Interactions
Molecules, 2019 The replication of a virus within its host cell involves numerous interactions between viral and cellular factors, which have to be tightly controlled in space and time.
Thorsten G. Müller +2 more
doaj +1 more source
Regaining the FORS: optical ground-based transmission spectroscopy of the exoplanet WASP-19b with VLT+FORS2 [PDF]
, 2015 In the past few years, the study of exoplanets has evolved from being pure discovery, then being more exploratory in nature and finally becoming very quantitative. In particular, transmission spectroscopy now allows the study of exoplanetary atmospheres.
Ancker, M. E. Van den +6 more
core +2 more sources
An HIV-1 capsid binding protein TRIM11 accelerates viral uncoating [PDF]
, 2016 Additional file 1: Figure S1. TRIM11 expression levels in different cells. HEK293, THP-1, PMA treated THP-1 cells and Jurkat cells were lysed with cell lysis buffer.
Binlian Sun +4 more
core +2 more sources
Viruses, 2021 The human immunodeficiency virus type 1 (HIV-1) capsid and its disassembly, or capsid uncoating, has remained an active area of study over the past several decades. Our understanding of the HIV-1 capsid as solely a protective shell has since shifted with
Zachary Ingram +2 more
doaj +1 more source