Results 51 to 60 of about 15,312 (202)
HIV-1 capsid uncoating initiates after the first strand transfer of reverse transcription [PDF]
, 2016 BACKGROUND: Correct disassembly of the HIV-1 capsid shell, called uncoating, is increasingly recognised as central for multiple steps during retroviral replication.
Cosnefroy, Ophélie +5 more
core +1 more source
Host cell factors regulate HIV-1 uncoating.
, 2018 The HIV-1 virion, which contains the CypA, ERK2, and eEF1A host proteins that regulate uncoating, binds and fuses with the host cell membrane, and the core is released into the cytoplasm.
David Harrich (37749) +1 more
core +1 more source
Fluorescence Microscopy Assay to Measure HIV-1 Capsid Uncoating Kinetics in vitro
Bio-Protocol, 2019 The stability of the HIV-1 capsid and the spatiotemporal control of its disassembly, a process called uncoating, need to be finely tuned for infection to proceed.
Chantal Márquez +6 more
doaj +1 more source
Adenovirus flow in host cell networks [PDF]
Open Biology, 2019 Viruses are obligatory parasites that take advantage of intracellular niches to replicate. During infection, their genomes are carried in capsids across the membranes of host cells to sites of virion production by exploiting cellular behaviour and ...
Justin W. Flatt, Sarah J. Butcher
doaj +1 more source
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
Interdisciplinary Medicine, EarlyView.This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
Current models for HIV-1 and MLV uncoating.
, 2021 Incoming viral cores (HIV-1, left columns and MLV, right column) surrounded by a CA lattice (orange hexagons) contain the viral RNA (red) coated with nucleocapsid (light blue), as well as the viral enzymes, protease (yellow), reverse transcriptase (light
Kate N. Bishop (11457941) +5 more
core +1 more source
Iflaviruses in arthropods: when small is mighty
Insect Science, EarlyView.Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia +3 more
wiley +1 more source
, 2019 The HIV-1 capsid has been recognised as an attractive antiviral target due to its central role during infection. It acts as a shield to protect the viral genome, facilitates reverse transcription, engages with the nuclear pore complex, and directs ...
Marquez Badilla, Chantal
core +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Botrytis cinerea is a widespread plant pathogenic ascomycete that causes grey mould in over 1400 species and impacts global crop yields. Double‐stranded RNA (dsRNA)‐induced gene silencing is a promising technology for pest control, but efficient delivery remains a major challenge.
Mei Guan +7 more
wiley +1 more source
EPS8 facilitates uncoating of influenza A virus [PDF]
Cell Reports, 2019 SUMMARY All viruses balance interactions between cellular machinery co-opted to support replication and host factors deployed to halt the infection. We used gene correlation analysis to perform an unbiased screen for host factors involved in influenza A virus (FLUAV) infection.
Larson, Gloria P. +9 more
openaire +3 more sources