Results 41 to 50 of about 31,798 (239)

Thymic development of human natural killer T cells: recent advances and implications for immunotherapy

open access: yesFrontiers in Immunology
Invariant natural killer T (iNKT) cells are a subset of lipid-reactive, unconventional T cells that have anti-tumor properties that make them a promising target for cancer immunotherapy.
Daniel G. Pellicci   +10 more
doaj   +1 more source

CD1b glycoprotein, a crucial marker of thymocyte development during T cell maturation in cynomolgus monkeys

open access: yesScientific Reports, 2023
Phenotypic markers that denote different developmental stages of thymocytes are important for understanding T cell development in the thymus. Here, we show that CD1b is a critical discriminator of thymocyte maturation stage in cynomolgus monkeys.
Sung Min Choi   +4 more
doaj   +1 more source

Development of Stem Cell-Derived Immune Cells for Off-the-Shelf Cancer Immunotherapies

open access: yesCells, 2021
Cell-based cancer immunotherapy has revolutionized the treatment of hematological malignancies. Specifically, autologous chimeric antigen receptor-engineered T (CAR-T) cell therapies have received approvals for treating leukemias, lymphomas, and multiple
Yan-Ruide Li   +4 more
doaj   +1 more source

Unconventional T Cell Immunity in the Lungs of Young Children with Cystic Fibrosis

open access: yesFrontiers in Bioscience-Landmark, 2022
Background: People with Cystic Fibrosis (CF) develop pulmonary inflammation, chronic infection and structural lung damage early in life, with these manifestations being prevalent among preschool children and infants.
Rebecca McElroy   +7 more
doaj   +1 more source

Simultaneous Enhancement of Performance and Stability in Dual‐Gate a‐IGZO Thin‐Film Transistors via Single‐Step Laser Annealing for Capacitor‐Less DRAM

open access: yesAdvanced Functional Materials, EarlyView.
A single‐step laser annealing strategy is presented for dual‐gate a‐IGZO TFTs. The steep thermal gradient induces graded oxygen doping in the channel and simultaneous WOx removal at the contacts, enabling concurrent interface and contact engineering.
Sihyeon Kwon   +9 more
wiley   +1 more source

The Conventional Nature of Non-MHC-Restricted T Cells

open access: yesFrontiers in Immunology, 2018
The definition “unconventional T cells” identifies T lymphocytes that recognize non-peptide antigens presented by monomorphic antigen-presenting molecules.
Marco Lepore   +2 more
doaj   +1 more source

ZBTB Transcription Factors: Key Regulators of the Development, Differentiation and Effector Function of T Cells

open access: yesFrontiers in Immunology, 2021
The development and differentiation of T cells represents a long and highly coordinated, yet flexible at some points, pathway, along which the sequential and dynamic expressions of different transcriptional factors play prominent roles at multiple steps.
Zhong-Yan Cheng   +4 more
doaj   +1 more source

Emerging Post‐CMOS Hardware Neurons for Brain‐Inspired Computing: Devices, Circuits, and System Integration

open access: yesAdvanced Functional Materials, EarlyView.
The physical realization of artificial neurons is a critical challenge for energy‐efficient neuromorphic computing. This review presents a comprehensive analysis of the evolution of artificial neuron implementations from conventional CMOS to emerging post‐CMOS technologies.
Kannan Udaya Mohanan   +4 more
wiley   +1 more source

Unified Pressure and Field Response Across Distinct Charge‐Order Regimes in Ti‐Doped CsV3Sb5

open access: yesAdvanced Functional Materials, EarlyView.
We microscopically investigate the interplay between charge order and superconductivity in a kagome superconductor across regimes of long‐ and short‐range charge order. Hydrostatic‐pressure and magnetic‐field μSR$\mu{\rm SR}$ measurements reveal remarkably similar superconducting and normal‐state time‐reversal‐symmetry‐breaking responses in both ...
P. Kral   +12 more
wiley   +1 more source

Magneto‐Ionic Devices With Polymer‐Based Electrolytes

open access: yesAdvanced Functional Materials, EarlyView.
Polymer electrolytes are introduced for magneto‐ionic devices based on hydroxide and hydrogen ions. The magneto‐ionic effect results in a pronounced voltage‐controlled variation of coercivity in both devices. The switching speed is in the range of 100 ms.
Markus Gößler   +3 more
wiley   +1 more source

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