Results 141 to 150 of about 8,105,112 (196)

Dysregulation of the unfolded protein response (UPR) in the dorsolateral prefrontal cortex in elderly patients with schizophrenia. [PDF]

Mol Psychiatry, 2021
Kim P, Scott MR, Meador-Woodruff JH.
europepmc   +1 more source

Polyphenism Through RNA Chemical Modifications

Molecular Ecology, Volume 35, Issue 19, October 2026.
ABSTRACT Polyphenism, the capacity of a single genotype to produce discrete phenotypes in response to environmental cues, has long served as a model for understanding developmental plasticity. While classical studies have highlighted hormonal signalling and transcription‐factor‐driven gene regulatory networks that mediate these environmentally induced ...
Ralf Schneider, Ehsan Pashay Ahi
wiley   +1 more source

The mitochondrial unfolded protein response (UPR^mt): shielding against toxicity to mitochondria in cancer. [PDF]

J Hematol Oncol, 2022
Inigo JR, Chandra D.
europepmc   +1 more source

A Fusion Between Common Bean Phaseolin and the N‐Terminal Domain of Maize 16 kDa Gamma Zein: Clues for Designing Nutritionally Improved Seed Storage Proteins

Plant Biotechnology Journal, Volume 24, Issue 10, Page 5408-5424, October 2026.
ABSTRACT Increasing the nutritional value of seed storage proteins (SSPs) has been largely hindered by limited knowledge of how the features of the various SSP domains determine high accumulation in protein storage vacuoles (PSV) or as endoplasmic reticulum (ER)‐located insoluble protein bodies (PB).
Emma Costa, Lucrezia Luciani, Mahsa Taghipour Rahimi, Alessandro Vitale, Emanuela Pedrazzini   +4 more
wiley   +1 more source

SIRT1 in Neurodegenerative Diseases: Molecular Mechanisms, Disease Relevance, and Therapeutic Potential

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
SIRT1, an NAD+‐dependent deacetylase, supports cognitive resilience by coordinating neuroprotection, synaptic plasticity, autophagy–lysosomal proteostasis, and mitochondrial energy homeostasis. Reduced or dysregulated SIRT1 is associated with protein aggregation, neuroinflammation, mitochondrial dysfunction, synaptic loss, and cognitive decline in ...
Jiabin Duan, Jiaqi Liu, Qingsheng Meng, Jiahao Liu, Sitian Yang, Fang Zhou, Jing Cao   +6 more
wiley   +1 more source

Cucumber Mosaic Virus Promotes Sphingolipid Biosynthesis to Alleviate Host Unfolded Protein Response (UPR)-Mediated Immunity. [PDF]

Mol Plant Pathol
Yao J, Wu S, Gao S, Xiang Z, Wang Q, Ye F, Liao Q, Gu Z, Du Z.   +8 more
europepmc   +1 more source

Hijacking the unfolded protein response (UPR) pathway: Balancing viral infection and host cell survival. [PDF]

J Biol Chem
Chen H, Liu D, Hua J, Wu M, Hua Y, Feng C, He Z, Moffett P, Zhang K.   +8 more
europepmc   +1 more source

Unfolded protein response (UPR) integrated signaling networks determine cell fate during hypoxia. [PDF]

Cell Mol Biol Lett, 2020
Bartoszewska S, Collawn JF.
europepmc   +1 more source

Regulation of Autophagy by the Unfolded Protein Response

, 2017
Autophagy is a highly conserved cellular response which allows the cell to degrade and recycle cellular proteins in an orderly manner. During autophagy cellular components are assembled into membrane-enclosed autophagasomes, which eventually fuses with ...
Lang, Irene, Kim, Chelsea, Min, Christy, Dong, Jackie, Kim, Jeff, Lee, Erin, Limhengco, Winston, Choi, James, Lewis, Emika   +8 more
core  

RETRACTED: Autoadaptive ER-Associated Degradation Defines a Preemptive Unfolded Protein Response Pathway

Folding-defective proteins must be cleared efficiently from the endoplasmic reticulum (ER) to prevent perturbation of the folding environment and to maintain cellular proteostasis.
Bernasconi, Riccardo, Galli, Carmela, Molinari, Maurizio, Kokame, Koichi   +3 more
core   +1 more source