Results 71 to 80 of about 101,011 (227)
Nature Communications, 2020 Developing novel thermometry techniques for nanoscale temperature measurements are vital for realizing efficient thermal management of nanoscale devices.
Karl Ridier +7 more
doaj +1 more source
Avaliação da transcrição de grp78/bip em células de indivíduos HIV positivos sob diferentes esquemas terapêuticos [PDF]
, 2014 TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.retículo endoplasmático é responsável pela síntese, dobramento e algumas modificações de proteínas que serão secretadas ou proteínas de membrana.
Dahmer, Mariane
core
Improving protein secretion with autophagy‐inhibiting or proteasome‐activating small molecules
Journal of Chemical Technology &Biotechnology, EarlyView.Abstract BACKGROUND Therapeutic proteins are produced frequently by mammalian cells in large‐scale bioreactors. As a result, producer cells are exposed to a chemically (nutrients, gas exchange, target protein overexpression) and physically (shear due to mixing) stressful environment, which can lead to endoplasmic reticulum (ER) stress and loss of ...
R Chauncey Splichal +2 more
wiley +1 more source
The Journal of Humanistic Counseling, EarlyView.ABSTRACT This article examines the future place of humanistic counseling, assuming the successful mass deployment of artificial intelligence therapy chatbots (AITCs). We systematically identify the limitations of AITCs through the lens of Jean Baudrillard's view on simulacra and hyperreality and identify five collective psychosocial consequences of ...
Brett. D. Wilkinson, Andrew M. Brown
wiley +1 more source
The unfolded protein response in multiple sclerosis
Frontiers in Neuroscience, 2015 The unfolded protein response (UPR) occurs in response to endoplasmic reticulum (ER) stress caused by the accumulation of unfolded or misfolded proteins in the ER.
Wensheng eLin, Sarrabeth eStone
doaj +1 more source
UPR Signal Activation by Luminal Sensor Domains [PDF]
, 2013 The unfolded protein response (UPR) is a cell-signaling system that detects the accumulation of unfolded protein within the endoplasmic reticulum (ER) and initiates a number of cellular responses to restore ER homeostasis.
Marta Carrara +8 more
core +1 more source
A Humanistic Social Justice Critique of AI in Counseling
The Journal of Humanistic Counseling, EarlyView.ABSTRACT Humanistic counselors prioritize social justice, human contact, the therapeutic relationship, and unconditional positive regard for the client that supports the client and the client's identity community. In contrast, counseling using artificial intelligence (AI) is driven by internet information pertaining to the inquiry or command ...
Colette T. Dollarhide, Amber Baughman
wiley +1 more source
Tren Penggunaan TikTok Pada Kalangan Remaja Mahasiswa Jurusan Sosiologi Angkatan 2021 FISIP UPR [PDF]
, 2021 The high need for using Internet-based on gadgets causes teenagers to spend most of their time accessing social media. At this time the TikTok application is one of the social media trends that is often accessed by all ages, including teenagers.
Pebrianti, Anisa
core
WTAP‐Mediated m6A Modification of TXNDC5 mRNA Promotes Cervical Carcinogenesis
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT WT1‐associated protein (WTAP), a core component of the methyltransferase complex, is involved in various tumor pathological processes, but its specific mechanism in cervical cancer (CC) remains unclear. This study, based on single‐cell transcriptomic data (including 3 CC and 2 normal tissues), constructed a CC microenvironment cell atlas ...
Ling Chen +4 more
wiley +1 more source
BEAN ROOT COLONIZATION BY PSEUDOMONAS CEPACIA UPR 5C [PDF]
, 1994 BEAN ROOT COLONIZATION BY PSEUDOMONAS CEPACIA UPR 5CBEAN ROOT COLONIZATION BY PSEUDOMONAS CEPACIA UPR ...
Sánchez, Alfonsina
core +1 more source