Results 1 to 10 of about 22,592 (227)

Uridine Diphosphate Glucose (UDP-G) Activates Oxidative Stress and Respiratory Burst in Isolated Neutrophils [PDF]

Pharmaceuticals, 2023
The extracellular purinergic agonist uridine diphosphate glucose (UDP-G) activates chemotaxis of human neutrophils (PMN) and the recruitment of PMN at the lung level, via P2Y14 purinergic receptor signaling.
Fabiana Lairion, Claudio Carbia, Iris Maribel Chiesa, Christian Saporito-Magriña, Natalia Borda, Alberto Lazarowski, Marisa Gabriela Repetto   +6 more
doaj   +2 more sources

Thermodynamics of binding of divalent magnesium and manganese to uridine phosphates: implications for diabetes-related hypomagnesaemia and carbohydrate biocatalysis [PDF]

Chemistry Central Journal, 2008
Background Although the necessity of divalent magnesium and manganese for full activity of sugar nucleotidyltransferases and glycosyltransferases is well known, the role of these metal cations in binding the substrates (uridine 5'-triphosphate, glucose-1-
Pohl Nicola L, Camci-Unal Gulden, Zea Corbin J   +2 more
doaj   +2 more sources

Uridine diphosphate glucose confers oxidative stress tolerance in microalgae [PDF]

BMC Plant Biology
Background Microalgae, as major primary producers on Earth, are constantly exposed to oxidative stresses from various natural environments. These oxidative stresses often seriously threaten the productivity and species composition of microalgae. However,
Ruihao Zhang, Tengfei Xiao, Baohua Zhu, Chengxiang Kan, Xing Chen, Zihao Cao, Yan Zhao, Yun Li, Guanpin Yang, Kehou Pan   +9 more
doaj   +2 more sources

UDP-glucose and MRS2905 agonist-bound states of the purinergic P2Y14 receptor [PDF]

Communications Biology
P2Y14 receptors respond to uracil-diphosphate-hexose conjugates, yet how this receptor selectively recognizes both uracil-nucleotides and hexose moieties of diverse agonists remains unclear.
Jonathan F. Fay, Joseph Kousouros, Zhan-Guo Gao, Matteo Pavan, Paola Oliva, Asmita Pramanik, Clayton Meyer, Siva Hariprasad Kurma, Wen Xu, Brian Krumm, Kenneth A. Jacobson   +10 more
doaj   +2 more sources

Structural basis of collagen glucosyltransferase function and its serendipitous role in kojibiose synthesis [PDF]

Nature Communications
Collagen glucosyltransferases catalyze collagen glucosylation critical for biology and diseases, yet their structural regulation remains unclear. Here, we report crystal structures of a mimiviral collagen glucosyltransferase in its apo form and in ...
Jeong Seon Kim, Zhenhang Chen, Sara Andrea Espinosa Garcia, Christoph Buhlheller, Botao Zhang, Stephen J. Richards, Tingfei Chen, Jingjing Wu, Ronald C. Bruntz, Marisa E. Gilliam, Mitsuo Yamauchi, Bo Liang, Houfu Guo   +12 more
doaj   +2 more sources

Uridine diphosphate-glucose 4-epimerase encoding gene galE affects the pathogenicity and carbon metabolism of Ralstonia pseudosolanacearum

浙江大学学报. 农业与生命科学版, 2023
In order to clarify the pathogenic function of uridine diphosphate (UDP)-glucose 4-epimerase encoding gene galE on Ralstonia pseudosolanacearum, the association between galE and the pathogenic-related phenotypes, and the gene deletion effect on ...
ZHANG Hong, LIN Zhijian, ZHU Jindong, LIN Zhaomiao, LI Guoliang, XU Yongqing, LIU Zhonghua, QIU Yongxiang, QIU Sixin   +8 more
doaj   +1 more source

Studies on uridine-diphosphate-glucose [PDF]

Biochemical Journal, 1952
Blanco y ...
Paladini, Alejandro C., Leloir, Luis Federico   +1 more
openaire   +3 more sources

Genomic-Wide Identification and Characterization of the Uridine Diphosphate Glycosyltransferase Family in Eucommia ulmoides Oliver

Plants, 2021
Eucommia ulmoides Oliver is a woody plant with great economic and medicinal value. Its dried bark has a long history of use as a traditional medicinal material in East Asia, which led to many glycosides, such as aucubin, geniposide, hyperoside ...
Dan Ouyang, Lan-Chun Wang, Ting Tang, Hong Feng   +3 more
doaj   +1 more source

Identification of sucrose synthase from Micractinium conductrix to favor biocatalytic glycosylation

Frontiers in Microbiology, 2023
Sucrose synthase (SuSy, EC 2.4.1.13) is a unique glycosyltransferase (GT) for developing cost-effective glycosylation processes. Up to now, some SuSys derived from plants and bacteria have been used to recycle uridine 5′-diphosphate glucose in the ...
Kai Chen, Lei Lin, Ruiqi Ma, Jiajie Ding, Huayi Pan, Yehui Tao, Yan Li, Honghua Jia   +7 more
doaj   +1 more source

Chemical Oxidation of Uridine Diphosphate-Glucose to Uridine Diphosphate-Glucuronic Acid [PDF]

Nature, 1961
THE importance of uronic acids in carbohydrate metabolism has only recently begun to be elucidated. The metabolism of inositol and ascorbate is known to involve uronic acid intermediates1,2, and nucleotide-bound glucuronic acid has been implicated in hyaluronic acid synthesis3.
B, JACOBSON, E A, DAVIDSON
openaire   +2 more sources