Results 11 to 20 of about 2,335,681 (277)

Data on the inhibition of cell proliferation and invasion by the D2A-Ala peptide derived from the urokinase receptor [PDF]

Data in Brief, 2019
The data presented in this article are connected to our research article entitled “D2A-Ala peptide derived from the urokinase receptor exerts anti-tumoural effects in vitro and in vivo” (Furlan et al., 2018).
Federico Furlan, Gabriele Eden, Marco Archinti, Ralitsa Arnaudova, Giuseppina Andreotti, Valentina Citro, Maria Vittoria Cubellis, Andrea Motta, Bernard Degryse   +8 more
doaj   +2 more sources

Data on the regulation of moesin and merlin by the urokinase receptor (uPAR): Model explaining distal activation of integrins by uPAR [PDF]

Data in Brief, 2017
The data presented herein are connected to our research article (doi: 10.1016/j.biocel.2017.04.012) [1], in which we investigated the functional connections between the urokinase receptor (uPAR), and the ezrin/radixin/moesin (ERM) proteins, moesin and ...
Bernard Degryse, Mishan Britto, Chun Xu Shan, Robert G. Wallace, Keith D. Rochfort, Philip M. Cummins, Gerardene Meade, Ronan P. Murphy   +7 more
doaj   +2 more sources

Soluble urokinase receptor is a kidney-specific vasoconstrictorResearch in context [PDF]

EBioMedicine
Summary: Background: Soluble urokinase plasminogen activator receptor (suPAR) is an innate immune system-derived risk factor for acute and chronic kidney diseases.
Sebastian Buhl Rasmussen, Rasmus Bo Lindhardt, Georgina Gyarmati, Kirsten Madsen, Claus Bistrup, Lars Lund, Sisse Rye Ostrowski, Changli Wei, Janos Peti-Peterdi, Per Svenningsen, Jochen Reiser, Hanne Berg Ravn   +11 more
doaj   +2 more sources

Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells. [PDF]

Elife, 2017
The urokinase receptor (uPAR) is a glycosylphosphatidylinositol (GPI)-anchored protein that promotes tissue remodeling, tumor cell adhesion, migration and invasion.
van Veen M, Matas-Rico E, van de Wetering K, Leyton-Puig D, Kedziora KM, De Lorenzi V, Stijf-Bultsma Y, van den Broek B, Jalink K, Sidenius N, Perrakis A, Moolenaar WH.   +11 more
europepmc   +2 more sources

Prognostic Impact of Urokinase Plasminogen Activator Receptor Expression in Pancreatic Cancer: Malignant Versus Stromal Cells

Biomarker Insights, 2017
The urokinase plasminogen activator receptor (uPAR) has been proposed as a potential prognostic factor for various malignancies. The aim of this study is to assess the prognostic value of uPAR expression in neoplastic and stromal cells of patients with ...
Susanna WL de Geus, Victor M Baart, Martin C Boonstra, Peter JK Kuppen, Hendrica AJM Prevoo, Andrew P Mazar, Bert A Bonsing, Hans Morreau, Cornelis JH van de Velde, Alexander L Vahrmeijer, Cornelis FM Sier   +10 more
doaj   +2 more sources

Let-7 Family microRNAs Regulate the Expression of the Urokinase-Receptor in Acute Myeloid Leukemia Cells [PDF]

Cells
The urokinase-receptor (uPAR) exerts multiple functions supporting most cancer hallmarks. Increased uPAR expression is associated with an unfavorable prognosis in several cancer types, including hematologic malignancies. We previously reported that three
Anna Li Santi, Mariaevelina Alfieri, Luigia Meo, Pia Ragno   +3 more
doaj   +2 more sources

Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas [PDF]

Scientific Reports, 2017
The development of metastases is a multistep process that requires the activation of physiological and biochemical processes that govern migration, invasion and entry of metastatic cells into blood vessels.
Maria Vincenza Carriero, Katia Bifulco, Vincenzo Ingangi, Susan Costantini, Giovanni Botti, Concetta Ragone, Michele Minopoli, Maria Letizia Motti, Domenica Rea, Giosuè Scognamiglio, Gerardo Botti, Claudio Arra, Gennaro Ciliberto, Antonello Pessi   +13 more
doaj   +2 more sources

Soluble Urokinase Receptor and Chronic Kidney Disease. [PDF]

N Engl J Med, 2015
Hayek SS, Sever S, Ko YA, Trachtman H, Awad M, Wadhwani S, Altintas MM, Wei C, Hotton AL, French AL, Sperling LS, Lerakis S, Quyyumi AA, Reiser J.   +13 more
europepmc   +2 more sources

Soluble Urokinase Receptor and Liver Disease. [PDF]

Clin Liver Dis (Hoboken), 2019
Wei C, Zhu K, Reiser J.
europepmc   +4 more sources

Expression and crystallographic studies of the D1D2 domains of C4.4A, a homologous protein to the urokinase receptor. [PDF]

Acta Crystallogr F Struct Biol Commun, 2017
Chen S, Lin L, Yuan C, Gårdsvoll H, Kriegbaum MC, Ploug M, Huang M.   +6 more
europepmc   +3 more sources