Results 11 to 20 of about 3,172 (181)

Pomegranate Juice Ameliorates Dopamine Release and Behavioral Deficits in a Rat Model of Parkinson’s Disease

open access: yesBrain Sciences, 2021
Pomegranate juice (PJ) is a rich source of ellagitannins (ETs), precursors of colonic metabolite urolithin A, which are believed to contribute to pomegranate’s neuroprotective effect.
Małgorzata Kujawska   +8 more
doaj   +1 more source

RETRACTED: A Combination Therapy of Urolithin A+EGCG Has Stronger Protective Effects than Single Drug Urolithin A in a Humanized Amyloid Beta Knockin Mice for Late-Onset Alzheimer’s Disease

open access: yesCells, 2022
In the current study, for the first time, we study mitophagy enhancer urolithin A and a combination of urolithin A+green tea extract EGCG against human Aβ peptide-induced mitochondrial and synaptic, dendritic, inflammatory toxicities and behavioral ...
Sudhir Kshirsagar   +8 more
doaj   +1 more source

Sarcopenia and Muscle Aging: A Brief Overview [PDF]

open access: yesEndocrinology and Metabolism, 2020
The world is facing the new challenges of an aging population, and understanding the process of aging has therefore become one of the most important global concerns.
Tam Dao   +8 more
doaj   +1 more source

Isolation of Human Intestinal Bacteria Capable of Producing the Bioactive Metabolite Isourolithin A from Ellagic Acid

open access: yesFrontiers in Microbiology, 2017
Urolithins are intestinal microbial metabolites produced from ellagitannin- and ellagic acid-containing foods such as walnuts, strawberries, and pomegranates.
María V. Selma   +7 more
doaj   +1 more source

Constituents and Metabolites of a French Oak Wood Extract (Robuvit®) in Serum and Blood Cell Samples of Women Undergoing Hysterectomy

open access: yesFrontiers in Pharmacology, 2020
Ellagitannins are signature constituents of oak wood and their consumption has been associated with various health benefits. In vivo, they undergo metabolic degradation including gut microbial metabolism yielding urolithins.
Linda Volpp   +5 more
doaj   +1 more source

Interactions between Gut Microbiota and Polyphenols: New Insights into the Treatment of Fatigue

open access: yesMolecules, 2022
Fatigue seriously affects people’s work efficiency and quality of life and has become a common health problem in modern societies around the world. The pathophysiology of fatigue is complex and not fully clear.
Chuanhong Luo   +8 more
doaj   +1 more source

Urolithins: The Colon Microbiota Metabolites as Endocrine Modulators: Prospects and Perspectives

open access: yesFrontiers in Nutrition, 2022
Selective estrogen receptor modulators (SERMs) have been used in hormone related disorders, and their role in clinical medicine is evolving. Tamoxifen and raloxifen are the most commonly used synthetic SERMs, and their long-term use are known to create ...
Ravindran Vini   +8 more
doaj   +1 more source

Tissue deconjugation of urolithin A glucuronide to free urolithin A in systemic inflammation

open access: yesFood & Function, 2019
Urolithin A glucuronide is deconjugated to free urolithin A in systemic inflammation.
Ávila-Gálvez, María Ángeles   +3 more
openaire   +5 more sources

The Compound Specific Antibacterial Activities of Major Urolithins and Their Methyl Ethers

open access: yesJournal of the Turkish Chemical Society, Section A: Chemistry, 2021
The investigation of biological activities of natural products, particularly considering the secondary metabolites, continuously receives attention.
Hayrettin Ozan GÜLCAN   +4 more
doaj   +1 more source

Urolithin A, C, and D, but not iso‐urolithin A and urolithin B, attenuate triglyceride accumulation in human cultures of adipocytes and hepatocytes

open access: yesMolecular Nutrition & Food Research, 2016
ScopeUrolithins (Uro) are ellagic acid (EA)‐derived metabolites produced by gut microbes. There is a growing interest in the biological activities of Uro. Our aim was to evaluate the impacts of Uro on regulating triglyceride (TG) accumulation using cultures of primary human adipocytes and hepatoma Huh7 cells.Methods and resultsUroA, UroB, UroC, UroD ...
Kang, Inhae   +4 more
openaire   +3 more sources

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