Glucolipotocixity induces IL-1 β secretion which impairs pancreatic β-cell insulin secretion. Ellagic acid and urolithin A have strong anti-inflammatory effect on cells. Muscadine and amla are very good sources of ellagic acid. The present study examined
Srikanth Earpina +5 more
doaj +1 more source
Novel multimetabolite prediction of walnut consumption by a urinary biomarker model in a free-living population: the PREDIMED Study [PDF]
The beneficial impact of walnuts on human health has been attributed to their unique chemical composition. In order to characterize the dietary walnut fingerprinting, spot urine samples from two sets of 195 (training) and 186 (validation) individuals ...
Andrés Lacueva, Ma. Cristina +10 more
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Pomegranate ellagitannins inhibit α-glucosidase activity in vitro and reduce starch digestibility under simulated gastro-intestinal conditions [PDF]
Pomegranate extract was tested for its ability to inhibit α-amylase and α-glucosidase activity. Pomegranate extract strongly inhibited rat intestinal α-glucosidase in vitro whereas it was a weak inhibitor of porcine α-amylase. The inhibitory activity was
BELLESIA, ANDREA +2 more
core +1 more source
An abnormality in the Lin28/let-7a axis is relevant to the progression of hepatitis B virus (HBV)-positive hepatocellular carcinoma (HCC), which could be a novel therapeutic target for this malignant tumor.
Zhenpeng Qiu +5 more
doaj +1 more source
Perspective: Metabotyping-A Potential Personalized Nutrition Strategy for Precision Prevention of Cardiometabolic Disease [PDF]
Diet is an important, modifiable lifestyle factor of cardiometabolic disease risk, and an improved diet can delay or even prevent the onset of disease.
Agneta, Rostgaard-Hansen,, +15 more
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Urolithins are the gut microbiota metabolites of ellagitannins which are found in natural plants such as pomegranate, strawberry, and raspberry, and in nuts.
Hecheng Wang +6 more
doaj +1 more source
Digestive Stability of Tannin-Enriched Fraction of Rubus chingii Hu Fruits and Its Regulatory Effect on the Intestinal Microflora [PDF]
Tannin is the major active ingredient of the dried unripe fruits of Chinese raspberry (Rubus chingii Hu), Fupenzi in Chinese, and has the functions of lowering blood sugar, reducing blood lipid, resisting inflammation, delaying aging and preventing ...
JIA Xiaoyan, HU Pengpeng, WANG Peixin, DING Qiao, WANG Enhui, XIE Zuohua, TU Zongcai, ZHANG Lu
doaj +1 more source
Inhibitory effect of tannins from galls of Carpinus tschonoskii on the degranulation of RBL-2H3 Cells [PDF]
In this study, the anti-allergy potency of thirteen tannins isolated from the galls on buds of Carpinus tschonoskii (including two tannin derivatives) was investigated.
Han Junkyu +7 more
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Maternal pomegranate juice intake and brain structure and function in infants with intrauterine growth restriction: A randomized controlled pilot study. [PDF]
Polyphenol-rich pomegranate juice has been shown to have benefit as a neuroprotectant in animal models of neonatal hypoxic-ischemia. No published studies have investigated maternal polyphenol administration as a potential neuroprotectant in at-risk ...
Alexopoulos, Dimitrios +7 more
core +2 more sources
A widely distributed metalloenzyme class enables gut microbial metabolism of host- and diet-derived catechols. [PDF]
Catechol dehydroxylation is a central chemical transformation in the gut microbial metabolism of plant- and host-derived small molecules. However, the molecular basis for this transformation and its distribution among gut microorganisms are poorly ...
Balskus, Emily P +8 more
core +1 more source

