Results 31 to 40 of about 21,131,763 (241)
Gut metabolite Urolithin A mitigates ionizing radiation‐induced intestinal damage [PDF]
Journal of Cellular and Molecular Medicine, 2021 AbstractIonizing radiation (IR)‐induced intestinal damage is the major and common injury of patients receiving radiotherapy. Urolithin A (UroA) is a metabolite of the intestinal flora of ellagitannin, a compound found in fruits and nuts such as pomegranates, strawberries and walnuts.
Yuanyang Zhang +7 more
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Frontiers in Pharmacology, 2020 Ellagitannins are signature constituents of oak wood and their consumption has been associated with various health benefits. In vivo, they undergo metabolic degradation including gut microbial metabolism yielding urolithins.
Linda Volpp +5 more
doaj +1 more source
Urolithin A attenuates auditory cell senescence by activating mitophagy
Scientific Reports, 2022 AbstractAging of sensory organs is associated with a decline in mitochondrial function and the accumulation of dysfunctional mitochondria. Impaired mitophagy blocks the turnover of dysfunctional mitochondria and leads to their accumulation. Urolithin A (UA) induces mitophagy in various mammalian cells.
Sung Il Cho, Eu-Ri Jo, Hansoo Song
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Life, 2022 In our continued study on the anti-HIV activity of compounds present in CareVidTM, we report the HIV-1 integrase ((HIV-1 IN) inhibitory effects of pellitorine (1), oleuropein (2), magnoflorine (3), crotepoxide (4), ent-kaurane-16β,17-diol (5 ...
Winnie Rotich +5 more
doaj +1 more source
Frontiers in Microbiology, 2017 Urolithins are intestinal microbial metabolites produced from ellagitannin- and ellagic acid-containing foods such as walnuts, strawberries, and pomegranates.
María V. Selma +7 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Acute lung injury (ALI) is a life-threatening disease with high incidence and mortality rates. Urolithin A (UA) is a pomegranate intestinal flora metabolite with anti-inflammatory, antioxidant, and anti-aging properties.
Lejing Lou +8 more
doaj +1 more source
Effects of olive and pomegranate by-products on human microbiota : a study using the SHIME (R) in vitro simulator [PDF]
, 2019 Two by-products containing phenols and polysaccharides, a "pate" (OP) from the extra virgin olive oil milling process and a decoction of pomegranate mesocarp (PM), were investigated for their effects on human microbiota using the SHIME (R) system.
Daghio, Matteo +6 more
core +1 more source
Tissue deconjugation of urolithin A glucuronide to free urolithin A in systemic inflammation
Food & Function, 2019 Urolithin A glucuronide is deconjugated to free urolithin A in systemic inflammation.
M. A. Ávila-Gálvez +3 more
openaire +4 more sources
Diverse Phytochemicals and Bioactivities in the Ancient Fruit and Modern Functional Food Pomegranate (Punica granatum). [PDF]
, 2017 Having served as a symbolic fruit since ancient times, pomegranate (Punica granatum) has also gained considerable recognition as a functional food in the modern era. A large body of literature has linked pomegranate polyphenols, particularly anthocyanins
Tian, Li, Wu, Sheng
core +2 more sources
Molecular Nutrition & Food Research, 2016 ScopeUrolithins (Uro) are ellagic acid (EA)‐derived metabolites produced by gut microbes. There is a growing interest in the biological activities of Uro. Our aim was to evaluate the impacts of Uro on regulating triglyceride (TG) accumulation using cultures of primary human adipocytes and hepatoma Huh7 cells.Methods and resultsUroA, UroB, UroC, UroD ...
Kang, Inhae +4 more
openaire +3 more sources