Results 41 to 50 of about 2,363 (194)
Molecular Nutrition & Food Research, 2016 ScopeUrolithins (Uro) are ellagic acid (EA)‐derived metabolites produced by gut microbes. There is a growing interest in the biological activities of Uro. Our aim was to evaluate the impacts of Uro on regulating triglyceride (TG) accumulation using cultures of primary human adipocytes and hepatoma Huh7 cells.Methods and resultsUroA, UroB, UroC, UroD ...
Kang, Inhae +4 more
openaire +3 more sources
Scientific Reports, 2021 A series of urolithins derivatives were designed and synthesized, and their structures have been confirmed by 1H NMR, 13C NMR, and HR-MS. The inhibitory activity of these derivatives on phosphodiesterase II (PDE2) was thoroughly studied with 3-hydroxy-8 ...
Long Tang +8 more
doaj +1 more source
Herba Polonica, 2020 Fireweed (Epilobium angustifolium L.) is a well-known medicinal plant traditionally used in the treatment of urogenital diseases, stomach and liver disorders, skin problems, etc. E.
Dreger Mariola +3 more
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Urolithin A Is a Dietary Microbiota-Derived Human Aryl Hydrocarbon Receptor Antagonist
Metabolites, 2018 Urolithins (e.g., UroA and B) are gut microbiota-derived metabolites of the natural polyphenol ellagic acid. Urolithins are associated with various health benefits, including attenuation of inflammatory signaling, anti-cancer effects and repression of ...
Gulsum E. Muku +3 more
doaj +1 more source
Urolithins: The Gut Based Polyphenol Metabolites of Ellagitannins in Cancer Prevention, a Review
Frontiers in Nutrition, 2021 Cancer as a disease continues to ravage the world population without regard to sex, age, and race. Due to the growing number of cases worldwide, cancer exerts a significant negative impact on global health and the economy. Interestingly, chemotherapy has
Sami A. Al-Harbi +5 more
doaj +1 more source
Novel multimetabolite prediction of walnut consumption by a urinary biomarker model in a free-living population: the PREDIMED Study [PDF]
, 2017 The beneficial impact of walnuts on human health has been attributed to their unique chemical composition. In order to characterize the dietary walnut fingerprinting, spot urine samples from two sets of 195 (training) and 186 (validation) individuals ...
Andrés Lacueva, Ma. Cristina +10 more
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Mitophagy Activation by Urolithin A to Target Muscle Aging
Calcified Tissue International, 2023 AbstractThe age-related loss of skeletal muscle function starts from midlife and if left unaddressed can lead to an impaired quality of life. A growing body of evidence indicates that mitochondrial dysfunction is causally involved with muscle aging. Muscles are tissues with high metabolic requirements, and contain rich mitochondria supply to support ...
Julie Faitg +3 more
openaire +2 more sources
Pomegranate ellagitannins inhibit α-glucosidase activity in vitro and reduce starch digestibility under simulated gastro-intestinal conditions [PDF]
, 2014 Pomegranate extract was tested for its ability to inhibit α-amylase and α-glucosidase activity. Pomegranate extract strongly inhibited rat intestinal α-glucosidase in vitro whereas it was a weak inhibitor of porcine α-amylase. The inhibitory activity was
BELLESIA, ANDREA +2 more
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Persistence of anticancer activity in berry extracts after simulated gastrointestinal digestion and colonic fermentation [PDF]
, 2012 Fruit and vegetable consumption is associated at the population level with a protective effect against colorectal cancer. Phenolic compounds, especially abundant in berries, are of interest due to their putative anticancer activity.
A Gil-Izquierdo +53 more
core +3 more sources
Benefits of polyphenols on gut microbiota and implications in human health [PDF]
, 2017 The biological properties of dietary polyphenols are greatly dependent on their bioavailability that, in turn, is largely influenced by their degree of polymerization.
Andrés Lacueva, Ma. Cristina +4 more
core +1 more source