Results 1 to 10 of about 207,763 (257)

Kinetic proofreading at single molecular level: Aminoacylation of tRNA^{Ile} and the role of water as an editor [PDF]

, 2013
Proofreading/editing in protein synthesis is essential for accurate translation of information from the genetic code. In this article we present a theoretical investigation of efficiency of a kinetic proofreading mechanism that employs hydrolysis of the wrong substrate as the discriminatory step in enzyme catalytic reactions. We consider aminoacylation
Bagchi, Biman, Santra, Mantu
arxiv   +5 more sources

Valine metabolite, 3-hydroxyisobutyrate, promotes lipid metabolism and cell proliferation in porcine mammary gland epithelial cells [PDF]

Frontiers in Nutrition
Improving mammary gland epithelial cells proliferation through nutrition is an important approach for enhancing sow milk production and piglet growth. An intermediate metabolite of valine, 3-hydroxyisobutyrate (3-HIB), regulates cellular lipid metabolism.
Long Che, Long Che, Long Che, Le Liu, Mengmeng Xu, Zongze Fan, Lizhu Niu, Yujie Chen, Xueyuan Chang, Pan Zhou, Mengyun Li, Hongyu Deng, Wen Chen   +12 more
doaj   +2 more sources

Circulating branched-chain amino acids and the risk of major adverse cardiovascular events in the UK biobank [PDF]

Frontiers in Endocrinology
ObjectiveTo investigate the relationship between circulating branched-chain amino acids (BCAAs) and the risk of major adverse cardiovascular events (MACE) in a national population-based cohort study.MethodsUK Biobank, a prospective study involving 22 ...
Wanwan Sun, Ruilang Lin, Yiming Li, Ye Yao, Bin Lu, Yongfu Yu   +5 more
doaj   +2 more sources

Valine potentiates cefoperazone-sulbactam to kill methicillin-resistant Staphylococcus aureus [PDF]

mSystems
Metabolic state-reprogramming approach was extended from Gram-negative bacteria to Gram-positive bacterium methicillin-resistant Staphylococcus aureus (MRSA) for identifying desired reprogramming metabolites to synergize existing antibiotic killing to ...
Shao-hua Li, Yuan Tao, Zhi-cheng Yang, Huan-zhe Fu, Hui-yin Lin, Xuan-xian Peng, Hui Li   +6 more
doaj   +2 more sources

THE DIETARY INDISPENSABILITY OF VALINE

Journal of Biological Chemistry, 1939
William C. Rose, S. H. Eppstein
openalex   +3 more sources

THE BIOSYNTHESIS OF VALINE BY SACCHAROMYCES CEREVISIAE

Journal of Biological Chemistry, 1954
I. Rosabelle McManus
openalex   +4 more sources

ISOTOPE STUDIES ON THE METABOLISM OF VALINE

Journal of Biological Chemistry, 1955
David S. Kinnory, Yoshiro Takeda, David M. Greenberg   +2 more
openalex   +4 more sources

The effect of different levels of Valine in low protein diets on cellular and humoral immunity of broiler chickens [PDF]

Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2021
Different levels of valine in low protein diets have a significant effect on the immune system of broiler chickens. This experiment was performed to evaluate the effect of different levels of valine in low protein diets on the immune response of broiler ...
Khosrow Parsaeimehr, Mohsen Daneshyar, Parviz Farhoomand, Hosein Janmohammadi, Majid Olyayee   +4 more
doaj   +1 more source

Relationship Between Serum Amino Acid Levels and Bone Mineral Density: A Mendelian Randomization Study

Frontiers in Endocrinology, 2021
BackgroundThis study aimed to explore the association between serum amino acids (AAs) levels and bone mineral density (BMD).MethodsWe performed a two-sample Mendelian randomization (MR) analysis to analyze the associations between the levels of eight AAs
Zhiyong Cui, Zhiyong Cui, Zhiyong Cui, Hui Feng, Hui Feng, Hui Feng, Baichuan He, Baichuan He, Baichuan He, Jinyao He, Jinyao He, Jinyao He, Yun Tian, Yun Tian, Yun Tian   +14 more
doaj   +1 more source

The Selective LAT1 Inhibitor JPH203 Enhances Mitochondrial Metabolism and Content in Insulin-Sensitive and Insulin-Resistant C2C12 Myotubes

Metabolites, 2023
Population data have shown an association between higher circulating branched-chain amino acids (BCAA) and the severity of insulin resistance in people with diabetes.
Caroline N. Rivera, Carly E. Smith, Lillian V. Draper, Gabriela E. Ochoa, Rachel M. Watne, Andrew J. Wommack, Roger A. Vaughan   +6 more
doaj   +1 more source