Results 31 to 40 of about 234,227 (283)

Pass-back chain extension expands multimodular assembly line biosynthesis. [PDF]

open access: yes, 2020
Modular nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) enzymatic assembly lines are large and dynamic protein machines that generally effect a linear sequence of catalytic cycles.
Huan, Tao   +5 more
core  

Amino acid content and biomass productivity of selected weed species as an indicator of their response to herbicide stress

open access: yesActa Agrobotanica, 2013
Biomass reduction and amino acid content in plants of Papaver rhoeas L. and Stellaria media L. were investigated to evaluate response of these species to herbicide stress under various temperature (25/16 and 8/2 oC) and relative humidity (50 and 75 ...
Renata Kieloch   +2 more
doaj   +1 more source

Exploring Valine Metabolism in Astrocytic and Liver Cells: Lesson from Clinical Observation in TBI Patients for Nutritional Intervention

open access: yesBiomedicines, 2020
The utilization of alternative energy substrates to glucose could be beneficial in traumatic brain injury (TBI). Recent clinical data obtained in TBI patients reported valine, β-hydroxyisobutyrate (ibHB) and 2-ketoisovaleric acid (2-KIV) as three of the ...
Sarah Sonnay   +5 more
doaj   +1 more source

Investigating the causal association between branched-chain amino acids and Alzheimer's disease: A bidirectional Mendelian randomized study

open access: yesFrontiers in Nutrition, 2023
BackgroundThere are many metabolic pathway abnormalities in Alzheimer's disease (AD). Several studies have linked branched-chain amino acid (BCAA) metabolism disorders with AD but have not obtained consistent results.
Xiao-hang Qian   +10 more
doaj   +1 more source

Neighbouring residue effects on the ^(15)N chemical shifts of some aliphatic dipeptides [PDF]

open access: yes, 1975
The ^(15)N chemical shifts of a number of simple aliphatic dipeptides have been determined in a aqueous solution and while the amine nitrogen shift is independent of the nature of the neighbouring residue, the peptide nitrogen shift shows a marked ...
Loftus, Philip   +3 more
core   +1 more source

Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant - Implications for disease susceptibility to Creutzfeldt-Jakob disease [PDF]

open access: yes, 2004
The human PrP gene (PRNP) has two common alleles that encode either methionine or valine at codon 129. This polymorphism modulates disease susceptibility and phenotype of human transmissible spongiform encyphalopathies, but the molecular mechanism by ...
Abdessamad Tahiri-Alaoui   +56 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Antioxidant Activity of New Aramide Nanoparticles Containing Redox-Active <em>N</em>-phthaloyl Valine Moieties in the Hepatic Cytochrome P<sub>450</sub> System in Male Rats

open access: yesMolecules, 2012
We report the synthesis of aramide nanoparticles containing a chiral <em>N</em>-phthaloyl valine moiety and their antioxidant activities on hepatic contents of cytochrome P<sub>450</sub>, amidopyrene <em>N</em> ...
Hammed H. A. M. Hassan   +3 more
doaj   +1 more source

Structural characterization of the D290V mutation site in hnRNPA2 low-complexity-domain polymers. [PDF]

open access: yes, 2018
Human genetic studies have given evidence of familial, disease-causing mutations in the analogous amino acid residue shared by three related RNA binding proteins causative of three neurological diseases. Alteration of aspartic acid residue 290 of hnRNPA2
Kato, Masato   +5 more
core  

Dissociation of Valine Cluster Cations [PDF]

open access: yesThe Journal of Physical Chemistry A, 2020
Independently of the preparation method, for cluster cations of aliphatic amino acids, the protonated form MnH+ is always the dominant species. This is a surprising fact considering that in the gas phase, they dissociate primarily by the loss of 45 Da, i.e., the loss of the carboxylic group. In the present study, we explore the dissociation dynamics of
Lukas Tiefenthaler   +4 more
openaire   +3 more sources

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