Results 201 to 210 of about 60,096 (254)

Trypanosome variant surface glycoprotein genes expressed early in infection

Journal of Molecular Biology, 1985
We have studied further the genes for trypanosomal variant surface glycoproteins expressed during a chronic infection of rabbits with Trypanosoma brucei, strain 427. We show that there are three closely related chromosomal-internal isogenes for VSG 121; expression of one of these genes is accompanied by the duplicate transposition of the gene to a ...
A Y, Liu   +3 more
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The membrane form of variant surface glycoproteins of Trypanosoma brucei

Nature, 1983
African trypanosomes are parasitic protozoa which are enveloped by a surface coat consisting of a matrix of identical glycoprotein molecules. Variations in the composition of these variant surface glycoproteins (VSGs) allow the parasite to escape the host's immune system and render effective immunoprophylaxis improbable. However, underlying the surface
M L, Cardoso de Almeida, M J, Turner
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Changes in cell surface glycoproteins on variant hamster cell lines

International Journal of Biochemistry, 1979
Abstract 1. 1. Resistance to concanavalin A was accompanied by modifications to the fundamental growth and membrane-associated properties of two concanavalin A-resistant cell lines which were independently selected by either single step or cycling procedures. 2. 2.
H, Ceri, J A, Wright
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Solution properties of the variant surface glycoprotein of Trypanosoma brucei

Molecular and Biochemical Parasitology, 1986
The solution properties of the membrane form and soluble form of variant surface glycoproteins from Trypanosoma brucei have been compared. Solution cross-linking studies established that both forms are dimers, although dissociation of membrane-form variant surface glycoprotein can be promoted by certain ionic and zwitterionic detergents.
A M, Gurnett, J, Raper, M J, Turner
openaire   +2 more sources

Release and purification of trypanosoma brucei variant surface glycoprotein

Journal of Cellular Biochemistry, 1984
AbstractConditions affecting the solubilization of variant surface glycoprotein (VSG) from Trypanosoma brucei have been investigated. The results obtained form the basis for a convenient and efficient method for VSG purification. VSG release from the cell surface was temperature‐dependent, following osmotic lysis at 0 °C, and was inhibited by low ...
openaire   +2 more sources

Variable and conserved structural elements of trypanosome variant surface glycoproteins

Molecular and Biochemical Parasitology, 1992
The characterization of B cell epitopes on the trypanosome variant surface glycoprotein (VSG) rests on elucidation of variant specific amino acid sequences that may be exposed or buried as a result of the natural conformation of these molecules in the surface coat.
D M, Reinitz   +2 more
openaire   +2 more sources

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