Results 1 to 10 of about 21,939 (162)
Membrane lipid composition modulates the organization of VDAC1, a mitochondrial gatekeeper [PDF]
Communications BiologyVDACs, the most abundant proteins in the outer mitochondrial membrane (MOM), are crucial for mitochondrial physiology. VDAC regulate metabolite and ion exchange, modulate calcium homeostasis, and play roles in numerous cellular events such as apoptosis ...
Elodie Lafargue +8 more
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Single scores in the RT-based value-driven attentional capture paradigm have high reliability [PDF]
Scientific ReportsValue-driven attentional capture (VDAC) involves involuntary attention shifts towards neutral stimuli previously associated with rewards. This phenomenon is pertinent for various neuropsychiatric conditions. This study aims to evaluate the reliability of
Chung-Yi Shih +2 more
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Modulation of mitochondrial voltage dependent anion channel: studies on bilayer electrophysiology [PDF]
Frontiers in PhysiologyThe present paper is a review of the mitochondrial Voltage Dependent Anion Channel (VDAC), popularly known as mitochondrial porin, which is a protein that forms a passive diffusion ion channel across the outer membrane of the mitochondrion.
Daniel Tuikhang Koren +4 more
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Redox-dependent gating of VDAC by mitoNEET [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2019 MitoNEET is an outer mitochondrial membrane protein essential for sensing and regulation of iron and reactive oxygen species (ROS) homeostasis. It is a key player in multiple human maladies including diabetes, cancer, neurodegeneration, and Parkinson's ...
Jason T Stofleth, Fang Bai, Susmita Roy
exaly +2 more sources
Ten Years of High Resolution Structural Research on the Voltage Dependent Anion Channel (VDAC)—Recent Developments and Future Directions [PDF]
Frontiers in Physiology, 2018 Mitochondria are evolutionarily related to Gram-negative bacteria and both comprise two membrane systems with strongly differing protein composition. The major protein in the outer membrane of mitochondria is the voltage-dependent anion channel (VDAC ...
Kornelius Zeth +2 more
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Structural basis of apoptosis induction by the mitochondrial voltage-dependent anion channel [PDF]
Nature CommunicationsThe voltage-dependent anion channel (VDAC) is the main gateway for metabolites across the mitochondrial outer membrane. VDAC oligomers are connected to apoptosis induced by various stimuli.
Melina Daniilidis +8 more
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Сибирский онкологический журнал, 2022 Purpose to study the tumor-forming activity of wild-type MC F-7 cells carrying a full set of porins (VDAC 1, VDAC 2, VDAC 3), as well as their genetically modified cells, from which one of the isoforms was removed (MC F-7 VDAC 1 KO, MC F-7 VDAC 2 KO, MC ...
E. Yu. Mndlyan +8 more
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The Role of Voltage-Dependent Anion Channel in Mitochondrial Dysfunction and Human Disease
Cells, 2021 The voltage-dependent anion channel (VDAC) is a β-barrel membrane protein located in the outer mitochondrial membrane (OMM). VDAC has two conductance states: an open anion selective state, and a closed and slightly cation-selective state.
Joyce T. Varughese +2 more
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Frontiers in Physiology, 2021 Voltage-dependent anion-selective channel (VDAC) allows the exchange of small metabolites and inorganic ions across the mitochondrial outer membrane. It is involved in complex interactions that regulate mitochondrial and cellular functioning.
Andonis Karachitos +3 more
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In Silico Exploration of Alternative Conformational States of VDAC
Molecules, 2023 VDAC (Voltage-Dependent Anion-selective Channel) is the primary metabolite pore in the mitochondrial outer membrane (OM). Atomic structures of VDAC, consistent with its physiological “open” state, are β-barrels formed by 19 transmembrane (TM) β-strands ...
Carmen Mannella
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