Results 31 to 40 of about 22,016 (234)
VDAC proteomics: Post-translation modifications
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2012 Voltage-dependent anion channels are abundant mitochondrial outer membrane proteins expressed in three isoforms, VDAC1-3, and are considered as "mitochondrial gatekeepers". Most tissues express all three isoforms. The functions of VDACs are several-fold, ranging from metabolite and energy exchange to apoptosis.
Kerner, Janos +3 more
openaire +2 more sources
Phosphorothioate Oligonucleotides Block the VDAC Channel [PDF]
Biophysical Journal, 2007 Proapoptotic phosphorothioate oligonucleotides such as G3139 (an 18-mer) induce Bcl-2-independent apoptosis, perhaps partly via direct interaction with VDAC and reduction of metabolite flow across the mitochondrial outer membrane. Here, we analyzed the interactions at the molecular level.
Tan, Wenzhi +4 more
openaire +2 more sources
TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control [PDF]
, 2014 The 18-kDa TSPO (translocator protein) localizes on the outer mitochondrial membrane (OMM) and participates in cholesterol transport. Here, we report that TSPO inhibits mitochondrial autophagy downstream of the PINK1-PARK2 pathway, preventing essential ...
Anholt R +22 more
core +3 more sources
Plant VDAC: Facts and speculations
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2012 The voltage-dependent anion-selective channel (VDAC) is the most abundant protein in the mitochondrial outer membrane and the major transport pathway for a large variety of compounds ranging from ions to large polymeric molecules such as DNA and tRNA. Plant VDACs feature a secondary structure content and electrophysiological properties akin to those of
Homblé, Fabrice +2 more
openaire +3 more sources
Equalization-Based Digital Background Calibration Technique for Pipelined ADCs [PDF]
, 2014 In this paper, we present a digital background calibration technique for pipelined analog-to-digital converters (ADCs). In this scheme, the capacitor mismatch, residue gain error, and amplifier nonlinearity are measured and then corrected in digital ...
Moosazadeh, Tohid +3 more
core +1 more source
Apoptosis: it's BAK to VDAC [PDF]
EMBO reports, 2009 VDAC's role in Bak‐dependent mitochondrial outer membrane permeabilization (MOMP) is controversial. Gordon Shore makes sense of it all in light of an EMBO reports paper that shows that VDAC mediates mitochondrial recruitment of Bak, thereby controlling tBid‐induced MOMP.
openaire +2 more sources
Severe hepatopathy and neurological deterioration after start of valproate treatment in a 6-year-old child with mitochondrial tryptophanyl-tRNA synthetase deficiency [PDF]
, 2018 Background: The first subjects with deficiency of mitochondrial tryptophanyl-tRNA synthetase (WARS2) were reported in 2017. Their clinical characteristics can be subdivided into three phenotypes (neonatal phenotype, severe infantile onset phenotype ...
De Bruyne, Ruth +9 more
core +1 more source
The role of glutamate release on voltage-dependent anion channels (VDAC)-mediated apoptosis in an eleven vessel occlusion model in rats. [PDF]
PLoS ONE, 2010 Voltage-dependent anion channel (VDAC) is the main protein in mitochondria-mediated apoptosis, and the modulation of VDAC may be induced by the excessive release of extracellular glutamate.
Eunkuk Park +7 more
doaj +1 more source
Biomolecules, 2021 It has become impossible to review all the existing literature on Voltage-Dependent Anion selective Channel (VDAC) in a single article. A real Renaissance of studies brings this protein to the center of decisive knowledge both for cell physiology and ...
Vito De Pinto
doaj +1 more source
Solute channels of the outer membrane: from bacteria to chloroplasts [PDF]
, 2007 Chloroplasts, unique organelles of plants, originated from endosymbiosis of an ancestor of today's cyanobacteria with a mitochondria-containing host cell. It is assumed that the outer envelope membrane, which delimits the chloroplast from the surrounding
Aljamal J.A. +8 more
core +1 more source