Results 11 to 20 of about 8,038 (173)
Versican Expression during Synovial Joint Morphogenesis [PDF]
International Journal of Biological Sciences, 2007 The extracellular matrix (ECM) plays a critical role in governing cell behavior and phenotype during limb skeletogenesis. Chondroitin sulfate proteoglycans (Cspgs) are highly expressed in the ECM of precartilage mesenchymal condensations and are ...
John B. Shepard, Heidi A. Krug, Brooklynn A. LaFoon, Stanley Hoffman, Anthony A. Capehart
doaj +4 more sources
Chondroitin Sulfate Proteoglycans in CNS Development and Pathophysiology. [PDF]
J Neurosci ResChondroitin sulfate proteoglycans (CSPGs) are critical components of the extracellular matrix in the central nervous system (CNS). In the developing CNS, CSPGs regulate neural precursor cells, neuronal migration, axon guidance, synapse organization, and peri‐neuronal net assembly.
Hosseini SM, Karimi-Abdolrezaee S.
europepmc +2 more sources
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on VCAN (versican), with data on DNA, on the protein encoded, and where the gene is implicated.
Hernández, D, Docampo, MJ, Bassols, A
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BMP-2 induces versican and hyaluronan that contribute to post-EMT AV cushion cell migration. [PDF]
PLoS ONE, 2013 Distal outgrowth and maturation of mesenchymalized endocardial cushions are critical morphogenetic events during post-EMT atrioventricular (AV) valvuloseptal morphogenesis.
Kei Inai +4 more
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Journal of Family Medicine and Primary Care, 2023 Objective: Versican is a chondroitin sulphate proteoglycan with raised expression at site of inflammation, and uterine fibroids are associated with local inflammation. Hence, this study aimed to estimate serum Versican levels in pre-menopausal women with
Pratima Jasti +3 more
doaj +1 more source
Increased renal versican expression is associated with progression of chronic kidney disease. [PDF]
PLoS ONE, 2012 Novel prognostic markers for progression of kidney disease are needed to distinguish patients who might benefit from a more aggressive nephroprotective therapy.
Michael Rudnicki +12 more
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Versican Mediates Mesenchymal-Epithelial Transition [PDF]
Molecular Biology of the Cell, 2006 Versican is a large extracellular chondroitin sulfate proteoglycan that belongs to the family of lecticans. Alternative splicing of versican generates at least four isoforms named V0, V1, V2, and V3. We show here that ectopic expression of versican V1 isoform induced mesenchymal-epithelial transition (MET) in NIH3T3 fibroblasts, and inhibition of ...
Wang, Sheng +7 more
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Gene Expression and Immunochemistry Analysis of ADAMTS-1 and Versican in Ameloblastoma
International Journal of Dentistry, 2022 Background. Ameloblastoma is a benign but locally invasive odontogenic epithelial tumor, associated with a high recurrence rate after treatment. The action of enzymes of the metalloproteinase family is important to the degraded extracellular matrix ...
Osvaldo Rodrigues de Souza Neto +4 more
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Versican Degradation and Vascular Disease [PDF]
Trends in Cardiovascular Medicine, 2006 Versican is an abundant proteoglycan in the blood vessel wall that is increased after vascular injury and accumulates in advanced atherosclerotic plaques. Versican is a large molecule with domains that mediate binding to cytokines, enzymes, lipoproteins, other extracellular matrix molecules, and signaling receptors.
Richard D, Kenagy +2 more
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Immunohistochemical and biochemical assay of versican in human sound predentine/dentine matrix
European Journal of Histochemistry, 2009 Aim of this study was to investigate the distribution of versican proteoglycan within the human dentine organic matrix by means of a correlative immunohistochemical analysis with field emission in-lens scanning electron microscope (FEI-SEM), transmission
A. Ruggeri +9 more
doaj +3 more sources