Results 31 to 40 of about 8,038 (173)
Versican modulates tumor-associated macrophage properties to stimulate mesothelioma growth
OncoImmunology, 2019 Versican promotes experimental tumor growth through cell- and non cell-autonomous mechanisms. Its role in mesothelioma progression has not been investigated so far.
Apostolos G. Pappas +8 more
doaj +1 more source
Inflammation Amplification by Versican: The First Mediator [PDF]
International Journal of Molecular Sciences, 2012 The effects of inflammation may not always benefit the individual. Its amplifying nature represents a highly regulated biological program, and the inflammatory microenvironment is its essential component. Growing evidence suggests that the ECM (extracellular matrix) is important for the early steps of inflammation.
Zhang, Zhenwei +2 more
openaire +2 more sources
Different mRNA and Protein Expression of Versican in TGF-β1-treated Prostate Cancer Cells
Forbes Tıp Dergisi, 2022 Objective: Cellular heterogeneity of tumors stems from cell populations expressing a unique set of proteins defective genetic and epigenetic networks.
Burak SONER +5 more
doaj +1 more source
The biochemistry and immunohistochemistry of versican [PDF]
, 2018 Versican is a chondroitin sulfate proteoglycan found in the extracellular matrix that is important for changes in cell phenotype associated with development and disease. Versican has been shown to be involved in cardiovascular disorders, as well as lung disease and fibrosis, inflammatory bowel disease, cancer, and several other diseases that have an ...
Stephen P, Evanko +4 more
openaire +2 more sources
Repression of Versican Expression by MicroRNA-143 [PDF]
Journal of Biological Chemistry, 2010 Smooth muscle cells (SMCs) retain remarkable plasticity to undergo phenotypic modulation in which the expression of smooth muscle markers is markedly attenuated while conversely expression of extracellular matrix (ECM) is dramatically up-regulated. Myocardin is perhaps the most potent transcription factor for stimulating expression of smooth muscle ...
Xiaobo, Wang, Guoqing, Hu, Jiliang, Zhou
openaire +2 more sources
Frontiers in Oncology, 2019 Versican and tumor-associated macrophages (TAMs) are involved in growth and metastases in several cancers. Here, we investigated the potential role of versican, a matrix proteoglycan, and its correlation with TAMs infiltrates in different stages of two ...
Diego Carlos dos Reis +13 more
doaj +1 more source
Versican and the control of inflammation
Matrix Biology, 2014 Versican is an extracellular matrix (ECM) proteoglycan that interacts with cells by binding to non-integrin and integrin receptors and to other ECM components that associate with the cell surface. Recent studies have shown also that versican interacts with myeloid and lymphoid cells promoting their adhesion and production of inflammatory cytokines ...
Wight, Thomas N. +2 more
openaire +2 more sources
Versican vs versikine: tolerance vs attack [PDF]
Blood, 2016 In this issue of Blood, Hope et al demonstrate the differential influence of versican and its proteolytic derivate, versikine, on the immune system.
openaire +2 more sources
BMC Veterinary Research, 2012 Background Components of the extracellular matrix have been studied in an attempt to elucidate the mechanisms involved in the biological behaviour of tumours.
Damasceno Karine A +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source