Results 1 to 10 of about 893 (111)
Enhancing very long chain fatty acids production in Yarrowia lipolytica
Microbial Cell Factories, 2022 Background Very long chain fatty acids (VLCFA) and their derivatives are industrially attractive compounds. The most important are behenic acid (C22:0) and erucic acid (C22:1Δ13), which are used as lubricants, and moisturizers.
Peter Gajdoš +3 more
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Algae: Critical Sources of Very Long-Chain Polyunsaturated Fatty Acids [PDF]
Biomolecules, 2019 Polyunsaturated fatty acids (PUFAs), which are divided into n-3 and n-6 classes, are essential for good health in humans and many animals. They are metabolised to lipid mediators, such as eicosanoids, resolvins and protectins.
John L. Harwood
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Very Long Chain Fatty Acids Are Functionally Involved in Necroptosis [PDF]
Cell Chemical Biology, 2017 Necroptosis is a form of regulated cell death that is linked to various human diseases. Distinct membrane-related, thus lipid-dependent, alterations take place during necroptosis. However, little is known about the roles of specific lipids in this process. We used an untargeted LC-MS-based approach to reveal that distinct lipid species are regulated at
Laura R Parisi +2 more
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Interactions of very long-chain saturated fatty acids with serum albumin [PDF]
Journal of Lipid Research, 2002 The remarkable binding properties of serum albumin have been investigated extensively, but little is known about an important class of fatty acids, the very long-chain saturated fatty acids (VLCFA; >18 carbons). Although VLCFA are metabolized efficiently
Ji-Kyung Choi +5 more
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How very-long-chain fatty acids could signal stressful conditions in plants?
Frontiers in Plant Science, 2016 Although encountered in minor amounts in plant cells, very-long-chain fatty acids exert crucial functions in developmental processes. When their levels is perturbed by means of genetic approaches, marked phenotypic consequences that range from severe ...
Antoine de Bigault du Granrut +2 more
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Novel Cellular Functions of Very Long Chain-Fatty Acids: Insight From ELOVL4 Mutations
Frontiers in Cellular Neuroscience, 2019 Elongation of Very Long chain fatty acids-4 (ELOVL4) protein is a member of the ELOVL family of fatty acid elongases that is collectively responsible for catalyzing formation of long chain fatty acids.
Ferenc Deák +11 more
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Very long-chain fatty acids drive 1-deoxySphingolipid toxicity
Nature Communications1-Deoxysphingolipids (1-deoxySLs) are atypical sphingolipids formed when serine palmitoyltransferase incorporates L-alanine instead of L-serine. Elevated 1-deoxySLs are associated with hereditary sensory neuropathy type 1 and diabetic neuropathy, but the
Adam Majcher +13 more
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Very Long-Chain Fatty Acids in Yeast [PDF]
Journal of Bacteriology, 1973 Novel fatty acids ranging from 20 to 30 carbons have been found in Saccharomyces cerevisiae . These comprise 1 to 2% of the total fatty acid fraction.
J W, Welch, A L, Burlingame
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Omega 3: Should we indicate it in our patients?
Revista de la Sociedad Argentina de Diabetes, 2022 Lipids are identified as a fundamental component of the diet because they perform very important functions. They influence the modulation of immune functions and inflammatory processes; attributable to long-chain polyunsaturated fatty acids (long chain ...
Marta Milikowski
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Saturated very long-chain fatty acids regulate macrophage plasticity and invasiveness
Journal of Neuroinflammation, 2022 Saturated very long-chain fatty acids (VLCFA, ≥ C22), enriched in brain myelin and innate immune cells, accumulate in X-linked adrenoleukodystrophy (X-ALD) due to inherited dysfunction of the peroxisomal VLCFA transporter ABCD1.
Bettina Zierfuss +15 more
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