Results 51 to 60 of about 3,566 (133)
Pharmacogenetics of warfarin: A literature review [PDF]
КардиоСоматикаWarfarin is an oral indirect anticoagulant that is widely used for the prevention of thromboembolic events. Pharmacogenetic testing is the most promising approach to personalizing warfarin treatment. In this review, we aimed to summarize how the patients’
Nadezhda V. Izmozherova +4 more
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Biometrical Journal, Volume 68, Issue 2, April 2026.ABSTRACT Single gene mutations are increasingly being adopted as clinical biomarkers for the optimal application of various therapeutic areas (such as cancer and cardiovascular disease). A single nucleotide polymorphism (SNP), the most common type of genetic variation in human populations, can affect the abundance and function of gene products at the ...
Song Zhai +3 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 953-963, April 2026.Grapefruit juice is a well‐established inhibitor of cytochrome P450 (CYP) 3A4, but its effects on other CYP enzymes or organic anion transporting polypeptides (OATPs) are not fully characterized in humans. Recently, lingonberry powder was shown to induce murine CYP enzymes. We investigated the effects of lingonberry powder and grapefruit juice on seven
Laura Aurinsalo +7 more
wiley +1 more source
Zanco Journal of Medical SciencesBackground and objective: Warfarin is the primary anticoagulant used in patients undergoing heart valve replacement surgery. Genetic variations in the CYP2C9 and VKORC1 (Vitamin K Epoxide Reductase Complex Subunit 1) genes have a significant impact on ...
Zeina Salim Mahmood, Kawa Fareq Dizaye
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Screening and prevention of anticoagulant resistance development in house mice: A review [PDF]
Pesticidi i Fitomedicina, 2020 Unrestricted use of anticoagulants has resulted in rodents developing resistance to them. This has caused a series of problems regarding reduction in rodent populations, which has further implicated great economic losses and a serious threat to the ...
Blažić Tanja +2 more
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Romanian Journal of Laboratory Medicine, 2015 Antagoniștii vitaminei K (AVK) sunt utilizați pe scară largă pentru profilaxia primară și secundară a trombembolismului, efectul lor anticoagulant fiind monitorizat prin intermediul INR.
Brudașcă Ioana
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Евразийский Кардиологический Журнал, 2019 Анализ взаимосвязи между носительством определенных аллелей полиморфизмов CYP2C9*2 гена CYP2C9 и полиморфного маркера VKORC1 G(-1639)A гена VKORC1 с развитием ЧГ у пациентов узбекской национальности на фоне терапии варфарином (Вф).
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One Rare Warfarin Resistance Case and Possible Mechanism Exploration
Pharmacogenomics and Personalized Medicine, 2023 Li Zhao,1 Zhenguo Zhai,2 Pengmei Li1 1Pharmacy Department, China-Japan Friendship Hospital, Beijing, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, People’s Republic of ...
Zhao L, Zhai Z, Li P
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BMC Cardiovascular Disorders, 2018 Background The anticoagulation of atrial fibrillation catheter ablation during the perioperative stage does matter and should be treated with discretion. We aimed to assess impact of three important genes participating in vitamin K cycle (i.e.
Jiao Li +5 more
doaj +1 more source
Romanian Journal of Laboratory Medicine, 2014 Scop: Această cercetare are drept scop stabilirea unei corelaţii genotip-fenotip la pacienţii trataţi cu acenocumarol şi studierea factoriilor genetici (polimorfismele VKORC1 şi CYP2C9), care ar putea influenţa valorile INR în timpul iniţierii terapiei ...
Militaru Florentina Claudia +5 more
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