Results 51 to 60 of about 487 (135)

Shape Tuning of Magnetite Nanoparticles Obtained by Hydrothermal Synthesis: Effect of Temperature

Journal of Nanomaterials, Volume 2019, Issue 1, 2019., 2019
In this work, we present a simple and efficient method for pure phase magnetite (Fe3O4) nanoparticle synthesis. The phase structure, particle shape, and size of the samples were characterized by Raman spectroscopy (Rm), X‐ray diffraction (XRD), scanning electron microscopy (SEM), energy‐dispersive X‐ray (EDS), and transmission electron microscopy (TEM).
Nayely Torres-Gómez, Osvaldo Nava, Liliana Argueta-Figueroa, René García-Contreras, Armando Baeza-Barrera, Alfredo R. Vilchis-Nestor, Paulo Cesar Morais   +6 more
wiley   +1 more source

Plasmonic Sensing of Aqueous‐Divalent Metal Ions by Biogenic Gold Nanoparticles

Journal of Nanomaterials, Volume 2019, Issue 1, 2019., 2019
The chemical interaction between biogenic gold nanoparticles (AuNPs) and several metal (II) ions can be regarded as a practical, twofold, colorimetric, and plasmon resonance sensing method for the recognition of some divalent metal ions in aqueous solutions. The green synthesized AuNPs, using Camellia sinensis as a reducing agent, were characterized by
Luisa E. Silva-De Hoyos, Victor Sánchez-Mendieta, Alfredo R. Vilchis-Nestor, Miguel A. Camacho-López, Jésica Trujillo-Reyes, Miguel Avalos-Borja, Ilaria Fratoddi   +6 more
wiley   +1 more source

Anti‐ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen‐Induced Mouse Model of Rheumatoid Arthritis

Journal of Immunology Research, Volume 2018, Issue 1, 2018., 2018
Lymphocyte costimulation plays a central role in immunology, inflammation, and immunotherapy. The inducible T cell costimulator (ICOS) is expressed on T cells following peptide: MHC engagement with CD28 costimulation. The interaction of ICOS with its sole ligand, the inducible T cell costimulatory ligand (ICOSL; also known as B7‐related protein‐1 ...
Ronan O’Dwyer, Marina Kovaleva, Jiquan Zhang, John Steven, Emma Cummins, Deborah Luxenberg, Alfredo Darmanin-Sheehan, Miguel F. Carvalho, Matthew Whitters, Kenneth Saunders, Caroline J. Barelle, Ilaria Roato   +11 more
wiley   +1 more source

Marine-derived microbes and molecules for drug discovery

Inflammation and Regeneration, 2022
Increasing attention has been paid to marine-derived biomolecules as sources of therapeutics for autoimmune diseases. Nagasaki Prefecture has many islands and is surrounded by seas, straits, gulfs, bays, and coves, giving it the second longest coastline ...
Yoshimasa Tanaka, Megumi Nishikawa, Kaho Kamisaki, Saki Hachiya, Moeka Nakamura, Takahiro Kuwazuru, Susumu Tanimura, Kiyoshi Soyano, Kohsuke Takeda   +8 more
doaj   +1 more source

Improving the pharmacokinetic properties of biologics by fusion to an anti-HSA shark VNAR domain [PDF]

mAbs, 2012
Advances in recombinant antibody technology and protein engineering have provided the opportunity to reduce antibodies to their smallest binding domain components and have concomitantly driven the requirement for devising strategies to increase serum half-life to optimise drug exposure, thereby increasing therapeutic efficacy. In this study, we adopted
Mischa R, Müller, Kenneth, Saunders, Christopher, Grace, Macy, Jin, Nicole, Piche-Nicholas, John, Steven, Ronan, O'Dwyer, Leeying, Wu, Lam, Khetemenee, Yulia, Vugmeyster, Timothy P, Hickling, Lioudmila, Tchistiakova, Stephane, Olland, Davinder, Gill, Allan, Jensen, Caroline J, Barelle   +15 more
openaire   +2 more sources

Escherichia coli surface display for the selection of nanobodies

Microbial Biotechnology, Volume 10, Issue 6, Page 1468-1484, November 2017., 2017
Libraries of VHH genes encoding nanobodies have been traditionally cloned in phage display or yeast display systems. This review briefly describes these conventional approaches and focuses on the distinct properties of an E. coli display system developed in our laboratory, which combines the benefits of both phage display and yeast display systems ...
Valencio Salema, Luis Ángel Fernández
wiley   +1 more source

Synthesis and Characterization of TiO2 Modified with Polystyrene and Poly(3‐chloro‐2‐hydroxypropyl Methacrylate) as Adsorbents for the Solid Phase Extraction of Organophosphorus Pesticides

Journal of Chemistry, Volume 2016, Issue 1, 2016., 2016
Novel hybrid TiO2 particles were developed and assessed as an adsorbent for solid phase extraction (SPE) of organophosphorus pesticides (fensulfothion, parathion methyl, coumaphos, and diazinon) from spiked water. The sol‐gel method was used to synthesize TiO2 particles, which were coated with free‐radical polystyrene (PS) and poly(3‐chloro‐2 ...
Enrique Alejo-Molina, A. Rafael Vilchis-Néstor, David Muñoz-Rodríguez, Cristian Carrera-Figueiras, Jean-Marie Nedelec   +4 more
wiley   +1 more source

Study of the Performance of the Organic Extracts of Chenopodium ambrosioides for Ag Nanoparticle Synthesis

Journal of Nanomaterials, Volume 2016, Issue 1, 2016., 2016
There are many ways to obtain metal nanoparticles: biological, physical, and chemical ways and combinations of these approaches. Synthesis assisted with plant extracts has been widely documented. However, one issue that is under discussion refers to the metabolites responsible for reduction and stabilization that confine nanoparticle growth and prevent
Luis M. Carrillo-López, Ramón M. Soto-Hernández, Hilda A. Zavaleta-Mancera, Alfredo R. Vilchis-Néstor, Xuping Sun   +4 more
wiley   +1 more source

Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development

Frontiers in Immunology, 2017
The management of chronic inflammatory diseases, such as inflammatory bowel disease, psoriasis, and rheumatoid arthritis has significantly improved over the last decade with the clinical availability of anti-TNF-α biologics.
Obinna C. Ubah, John Steven, Marina Kovaleva, Laura Ferguson, Charlotte Barelle, Andrew J. R. Porter, Andrew J. R. Porter, Caroline J. Barelle   +7 more
doaj   +1 more source

The Molecular Toolbox for Linkage Type‐Specific Analysis of Ubiquitin Signaling

ChemBioChem, Volume 26, Issue 10, May 27, 2025.
Ubiquitin modifications regulate virtually all aspects of eukaryotic cell biology through an array of polyubiquitin chain signals that adopt distinct structures, enabling the individual polyubiquitin linkages to mediate specific functions in cells.
Julian Koch, Camilla Reiter Elbæk, Dominik Priesmann, Rune Busk Damgaard   +3 more
wiley   +1 more source