Results 71 to 80 of about 1,385 (169)

Synthesis and Characterization of TiO2 Modified with Polystyrene and Poly(3‐chloro‐2‐hydroxypropyl Methacrylate) as Adsorbents for the Solid Phase Extraction of Organophosphorus Pesticides

open access: yesJournal of Chemistry, Volume 2016, Issue 1, 2016., 2016
Novel hybrid TiO2 particles were developed and assessed as an adsorbent for solid phase extraction (SPE) of organophosphorus pesticides (fensulfothion, parathion methyl, coumaphos, and diazinon) from spiked water. The sol‐gel method was used to synthesize TiO2 particles, which were coated with free‐radical polystyrene (PS) and poly(3‐chloro‐2 ...
Enrique Alejo-Molina   +4 more
wiley   +1 more source

Production and efficacy of a low-cost recombinant pneumococcal protein polysaccharide conjugate vaccine. [PDF]

open access: yes, 2018
Streptococcus pneumoniae is the leading cause of bacterial pneumonia. Although this is a vaccine preventable disease, S. pneumoniae still causes over 1 million deaths per year, mainly in children under the age of five.
Abouelhadid, Sherif   +7 more
core   +3 more sources

Study of the Performance of the Organic Extracts of Chenopodium ambrosioides for Ag Nanoparticle Synthesis

open access: yesJournal of Nanomaterials, Volume 2016, Issue 1, 2016., 2016
There are many ways to obtain metal nanoparticles: biological, physical, and chemical ways and combinations of these approaches. Synthesis assisted with plant extracts has been widely documented. However, one issue that is under discussion refers to the metabolites responsible for reduction and stabilization that confine nanoparticle growth and prevent
Luis M. Carrillo-López   +4 more
wiley   +1 more source

Facile Solventless Synthesis of a Nylon‐6,6/Silver Nanoparticles Composite and Its XPS Study

open access: yesInternational Journal of Polymer Science, Volume 2013, Issue 1, 2013., 2013
Silver nanoparticles were synthesized and supported on thin nylon membranes by means of a simple method of impregnation and chemical reduction of Ag ions at ambient conditions. Particles of less than 10 nm were obtained using this methodology, in which the nylon fibers behave as constrained nanoreactors.
Raúl A. Morales-Luckie   +8 more
wiley   +1 more source

Central Nervous System Delivery of Antibodies and Their Single-Domain Antibodies and Variable Fragment Derivatives with Focus on Intranasal Nose to Brain Administration

open access: yesAntibodies, 2021
IgG antibodies are some of the most important biopharmaceutical molecules with a high market volume. In spite of the fact that clinical therapies with antibodies are broadly utilized in oncology, immunology and hematology, their delivery strategies and ...
Arghavan Soleimanizadeh   +2 more
doaj   +1 more source

From Multi‐Omics to Visualization and Beyond: Bridging Micro and Macro Insights in CAR‐T Cell Therapy

open access: yesAdvanced Science, Volume 12, Issue 20, May 29, 2025.
This review explores how multi‐omics, visualization technologies, and AI drive CAR‐T therapy from the micro to the macro level, from preclinical studies to clinical applications. The convergence of these approaches provides deeper insight into CAR‐T cell mechanisms, aids in structural optimization, and significantly enhances treatment efficacy and ...
Yuting Gong   +4 more
wiley   +1 more source

Study Design of the Microcirculatory Shock Occurrence in Acutely Ill Patients (microSOAP): an International Multicenter Observational Study of Sublingual Microcirculatory Alterations in Intensive Care Patients

open access: yesCritical Care Research and Practice, Volume 2012, Issue 1, 2012., 2012
Objective. Sublingual microcirculatory alterations are associated with an adverse prognosis in several critical illness subgroups. Up to now, single‐center studies have reported on sublingual microcirculatory alterations in ICU patient subgroups, but an extensive evaluation of the prevalence of these alterations is lacking.
Namkje A. R. Vellinga   +9 more
wiley   +1 more source

Theranostic vNAR-Based Immunoconjugates Achieve Selective Intracellular Cisplatin Delivery in Embedded 3D HER2-Positive Breast Cancer In Vitro Model

open access: yesPharmaceuticals
Background/Objectives: Precise intracellular delivery of chemotherapeutics remains a major challenge in HER2-positive breast cancer, where intratumoral heterogeneity and limited tissue penetration constrain efficacy.
Andrea C. Alfonseca-Ladrón de Guevara   +5 more
doaj   +1 more source

Single domain antibody: Development and application in biotechnology and biopharma

open access: yesImmunological Reviews, Volume 328, Issue 1, Page 98-112, November 2024.
Summary Heavy‐chain antibodies (HCAbs) are a unique type of antibodies devoid of light chains, and comprised of two heavy chains‐only that recognize their cognate antigen by virtue of a single variable domain also referred to as VHH, single domain antibody (sdAb), or nanobody (Nb).
Ting Yu   +4 more
wiley   +1 more source

Organized B cell sites in cartilaginous fishes reveal the evolutionary foundation of germinal centers [PDF]

open access: yes, 2023
The absence of germinal centers (GCs) in cartilaginous fishes lies at odds with data showing that nurse sharks can produce robust antigen-specific responses and affinity mature their B cell repertoires.
Beltran, Mariana   +8 more
core   +3 more sources

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