Frontiers in Immunology, 2019 Tumor necrosis factor-alpha (TNF-α), an established pro-inflammatory cytokine plays a central role in the induction and progression of several chronic inflammatory and autoimmune diseases.
Obinna C. Ubah +4 more
doaj +1 more source
Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature
Nanoscale, 2020 Anti-DLL4 VNAR targeted nanoparticles – a novel targeting ligand towards an under-investigated target.
Adam Leach +9 more
openaire +4 more sources
VNAR single-domain antibodies specific for BAFF inhibit B cell development by molecular mimicry [PDF]
Molecular Immunology, 2016 B cell-activating factor (BAFF) plays a dominant role in the B cell homeostasis. However, excessive BAFF promotes the development of autoreactive B-cells and several antibodies have been developed to block its activity. Bispecific antibodies with added functionality represent the next wave of biologics that may be more effective in the treatment of ...
Häsler, Julien +4 more
openaire +3 more sources
Malaysia Journal of Invention and Innovation, 2023 People may now instantly obtain any information they desire thanks to the advancements in technology. Unfortunately, technological development can also result in grave issues, such as irresponsible anti-vaccine advocates who disseminate incorrect ...
Siti Nur Irdina Alwi, Suzidiana Sulaiman
doaj +2 more sources
Efficient Construction and Effective Screening of Synthetic Domain Antibody Libraries
Methods and Protocols, 2019 Phage display is a powerful technique for drug discovery in biomedical research in particular for antibody libraries. But, several technical challenges are associated with the selection process.
Arghavan Solemani Zadeh +4 more
doaj +1 more source
Single Domain Antibodies as New Biomarker Detectors
Diagnostics, 2017 Biomarkers are defined as indicators of biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention. Biomarkers have been widely used for early detection, prediction of response after treatment, and for ...
Chiuan Herng Leow +5 more
doaj +1 more source
Development of a cationic polyethyleneimine-poly(lactic-co-glycolic acid) nanoparticle system for enhanced intracellular delivery of biologics. [PDF]
RSC Adv, 2023 Tracey SR +6 more
europepmc +1 more source
Humanized shark variable new antigen receptors (VNARs) [PDF]
Science-Business eXchange, 2013 openaire +1 more source
Construction and application of a multifunctional CHO cell platform utilizing Cre/lox and Dre/rox site-specific recombination systems. [PDF]
Front Bioeng Biotechnol, 2023 Zhang C +7 more
europepmc +1 more source
Chimeric Peptides from Californiconus californicus and Heterodontus francisci with Antigen-Binding Capacity: A Conotoxin Scaffold to Create Non-Natural Antibodies (NoNaBodies). [PDF]
Toxins (Basel), 2023 Dueñas S +11 more
europepmc +1 more source