Results 71 to 80 of about 691 (170)
Construction and evaluation of a synthetic
Protein ScienceAbstract Sharks produce a unique antibody type, whose variable domain (VNAR) is the smallest known antibody fragment. VNARs possess high affinity, stability, and tissue penetration, making them attractive for biomedical applications.
Zu‐Ying Liu +10 more
openaire +2 more sources
Frontiers in Immunology, 2023 IntroductionO-GlcNAcylation is a type of reversible post-translational modification on Ser/Thr residues of intracellular proteins in eukaryotic cells, which is generated by the sole O-GlcNAc transferase (OGT) and removed by O-GlcNAcase (OGA).
Xiaozhi Xi +21 more
doaj +1 more source
Ueg Week 2020 Poster Presentations
, 2020 United European Gastroenterology Journal, Volume 8, Issue S8, Page 144-887, October 2020.
wiley +1 more source
Frontiers in Immunology, 2019 Tumor necrosis factor-alpha (TNF-α), an established pro-inflammatory cytokine plays a central role in the induction and progression of several chronic inflammatory and autoimmune diseases.
Obinna C. Ubah +4 more
doaj +1 more source
Malaysia Journal of Invention and Innovation, 2023 People may now instantly obtain any information they desire thanks to the advancements in technology. Unfortunately, technological development can also result in grave issues, such as irresponsible anti-vaccine advocates who disseminate incorrect ...
Siti Nur Irdina Alwi, Suzidiana Sulaiman
doaj +2 more sources
Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature
Nanoscale, 2020 Anti-DLL4 VNAR targeted nanoparticles – a novel targeting ligand towards an under-investigated target.
Adam Leach +9 more
openaire +4 more sources
, 2014 Los fragmentos de anticuerpo de dominio sencillo (~12 kDa), han mostrado ventajas sobre las moléculas de anticuerpo convencionales (~150 kDa) respecto a su aplicación clínica.
Olivia Cabanillas Bernal
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Assays to obtain vNAR fragments for Coccidioides spp detection
, 2018 La fiebre del Valle de San Joaquín o Coccidioidomicosis (CM) es una enfermedad pulmonar causada por el hongo Coccidioides spp. La perturbación del suelo por humanos, animales o condiciones climáticas ocasiona la dispersión de esporas de Coccidioides en ...
JAMVIER BARUC LOPEZ TELLO
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Expresión recombinante de un dominio vNAR anti-EGFRvIII Epidermal Growth Factor Receptor presente en células tumorales, PAP realizado en el CIATEJ [PDF]
, 2023 Este proyecto, denominado "Expresión recombinante de un dominio vNAR anti-EGFRvIII (Epidermal Growth Factor Receptor) presente en células tumorales", tiene como propósito general extraer y aislar una proteína específica (vNAR R426) con el fin de ...
Urzúa-TorresSeptién, Andrés
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Effect of a VNAR anti-VEGF165 in the treatment of cancer
, 2018 Los VNARs se han probado como nuevos entes terapéuticos, basados en su estabilidad, capacidad de unión y penetración en los tejidos. El V13, un VNAR que reconoce al VEGF, se utilizó como molécula parental en la cual se insertaron cambios de aminoácidos ...
DALIA VANESSA MILLAN GOMEZ
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