Results 61 to 70 of about 487 (135)

Facile Solventless Synthesis of a Nylon‐6,6/Silver Nanoparticles Composite and Its XPS Study

open access: yesInternational Journal of Polymer Science, Volume 2013, Issue 1, 2013., 2013
Silver nanoparticles were synthesized and supported on thin nylon membranes by means of a simple method of impregnation and chemical reduction of Ag ions at ambient conditions. Particles of less than 10 nm were obtained using this methodology, in which the nylon fibers behave as constrained nanoreactors.
Raúl A. Morales-Luckie   +8 more
wiley   +1 more source

Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies

open access: yesFrontiers in Immunology, 2020
The B-cell receptor (BCR) is a key player of the adaptive immune system. It is a unique part of immunoglobulin (Ig) molecules expressed on the surface of B cells. In case of many B-cell lymphomas, the tumor cells express a tumor-specific and functionally
Arturo Macarrón Palacios   +8 more
doaj   +1 more source

From Multi‐Omics to Visualization and Beyond: Bridging Micro and Macro Insights in CAR‐T Cell Therapy

open access: yesAdvanced Science, Volume 12, Issue 20, May 29, 2025.
This review explores how multi‐omics, visualization technologies, and AI drive CAR‐T therapy from the micro to the macro level, from preclinical studies to clinical applications. The convergence of these approaches provides deeper insight into CAR‐T cell mechanisms, aids in structural optimization, and significantly enhances treatment efficacy and ...
Yuting Gong   +4 more
wiley   +1 more source

Study Design of the Microcirculatory Shock Occurrence in Acutely Ill Patients (microSOAP): an International Multicenter Observational Study of Sublingual Microcirculatory Alterations in Intensive Care Patients

open access: yesCritical Care Research and Practice, Volume 2012, Issue 1, 2012., 2012
Objective. Sublingual microcirculatory alterations are associated with an adverse prognosis in several critical illness subgroups. Up to now, single‐center studies have reported on sublingual microcirculatory alterations in ICU patient subgroups, but an extensive evaluation of the prevalence of these alterations is lacking.
Namkje A. R. Vellinga   +9 more
wiley   +1 more source

Single domain antibody: Development and application in biotechnology and biopharma

open access: yesImmunological Reviews, Volume 328, Issue 1, Page 98-112, November 2024.
Summary Heavy‐chain antibodies (HCAbs) are a unique type of antibodies devoid of light chains, and comprised of two heavy chains‐only that recognize their cognate antigen by virtue of a single variable domain also referred to as VHH, single domain antibody (sdAb), or nanobody (Nb).
Ting Yu   +4 more
wiley   +1 more source

Central Nervous System Delivery of Antibodies and Their Single-Domain Antibodies and Variable Fragment Derivatives with Focus on Intranasal Nose to Brain Administration

open access: yesAntibodies, 2021
IgG antibodies are some of the most important biopharmaceutical molecules with a high market volume. In spite of the fact that clinical therapies with antibodies are broadly utilized in oncology, immunology and hematology, their delivery strategies and ...
Arghavan Soleimanizadeh   +2 more
doaj   +1 more source

Rothe approach to the existence of solution of an ablation‐transpiration cooling control system

open access: yesInternational Journal of Stochastic Analysis, Volume 6, Issue 2, Page 161-179, 1993., 1993
A one dimensional ablation model with transpiration cooling control and nonlinear effect is studied, which is a distributed parameter control system with moving boundary and both governing equation and boundary conditions involving control variable. A solution is given by a Rothe approximation scheme.
Guo Bao Zhu
wiley   +1 more source

Construction and evaluation of a synthetic VNAR library for targeted antigen screening

open access: yesProtein Science
Abstract Sharks produce a unique antibody type, whose variable domain (VNAR) is the smallest known antibody fragment. VNARs possess high affinity, stability, and tissue penetration, making them attractive for biomedical applications.
Zu‐Ying Liu   +10 more
openaire   +2 more sources

Ueg Week 2020 Poster Presentations

open access: yes, 2020
United European Gastroenterology Journal, Volume 8, Issue S8, Page 144-887, October 2020.
wiley   +1 more source

Transportation of Single-Domain Antibodies through the Blood–Brain Barrier

open access: yesBiomolecules, 2021
Single-domain antibodies derive from the heavy-chain-only antibodies of Camelidae (camel, dromedary, llama, alpaca, vicuñas, and guananos; i.e., nanobodies) and cartilaginous fishes (i.e., VNARs).
Eduardo Ruiz-López   +1 more
doaj   +1 more source

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