Rothe approach to the existence of solution of an ablation‐transpiration cooling control system
A one dimensional ablation model with transpiration cooling control and nonlinear effect is studied, which is a distributed parameter control system with moving boundary and both governing equation and boundary conditions involving control variable. A solution is given by a Rothe approximation scheme.
Guo Bao Zhu
wiley +1 more source
Spartan Daily, November 22, 1996 [PDF]
Volume 107, Issue 61https://scholarworks.sjsu.edu/spartandaily/8917/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +5 more sources
Uveitis Therapy With Shark Variable Novel Antigen Receptor Domains Targeting Tumor Necrosis Factor Alpha or Inducible T-Cell Costimulatory Ligand [PDF]
Acknowledgments Supported by an unrestricted departmental grant from Research to Prevent Blindness (New York, NY), NEI K08EY023998 (KLP), P30-EY001730 (RVG; Bethesda, MD), by a grant from Elasmogen Limited (RVG), and with support from the Mark J.
Barelle, Caroline J. +7 more
core +1 more source
Recurrent Events Analysis With Data Collected at Informative Clinical Visits in Electronic Health Records [PDF]
Although increasingly used as a data resource for assembling cohorts, electronic health records (EHRs) pose many analytic challenges. In particular, a patient's health status influences when and what data are recorded, generating sampling bias in the ...
Huang, Chiung-Yu +3 more
core +1 more source
Ueg Week 2020 Poster Presentations
United European Gastroenterology Journal, Volume 8, Issue S8, Page 144-887, October 2020.
wiley +1 more source
Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature
Anti-DLL4 VNAR targeted nanoparticles – a novel targeting ligand towards an under-investigated target.
Adam Leach +9 more
openaire +5 more sources
Transportation of Single-Domain Antibodies through the Blood–Brain Barrier
Single-domain antibodies derive from the heavy-chain-only antibodies of Camelidae (camel, dromedary, llama, alpaca, vicuñas, and guananos; i.e., nanobodies) and cartilaginous fishes (i.e., VNARs).
Eduardo Ruiz-López +1 more
doaj +1 more source
Human TNF cytokine neutralization with a vNAR fromHeterodontus franciscishark: A potential therapeutic use [PDF]
The therapeutic use of single domain antibodies (sdAbs) is a promising new approach because these small antibodies maintain antigen recognition and neutralization capacity, have thermal and chemical stability and have good solubility. In this study, using phage display technology, we isolated a variable domain of a IgNAR (vNAR) from a Heterodontus ...
Tanya, Camacho-Villegas +4 more
openaire +2 more sources
Bamboo Shark as a Small Animal Model for Single Domain Antibody Production
The development of shark single domain antibodies (sdAbs) is hindered by the high cost and tediousness of large-sized shark farming. Here, we demonstrated white-spotted bamboo sharks (Chiloscyllium plagiosum) being cultivated commercially as a promising ...
Likun Wei +24 more
doaj +1 more source
Oriented attachment of VNAR proteins, Q2 via site-selective modification, on PLGA–PEG nanoparticles enhances nanoconjugate performance [PDF]
This work was partially funded through a US-Ireland R&D Partnership grant (STL/5010/14, MRC grant MC_PC_15013). JCFN is funded by the EU’s Horizon 2020 programme under Marie-Curie grant agreement 675007.
Barelle, Caroline +8 more
core +3 more sources

