Results 51 to 60 of about 14,132 (209)

Variable-number tandem-repeat markers for typing Mycobacterium intracellulare strains isolated in humans

BMC Microbiology, 2010
Background Mycobacterium intracellulare, a species of the Mycobacterium avium complex, may be the cause of severe lung, lymphatic node, skin and bone/joint infections, as well as bacteriemia.
Dauchy Frédéric-Antoine, Dégrange Sébastien, Charron Alain, Dupon Michel, Xin Yi, Bébéar Cécile, Maugein Jeanne   +6 more
doaj   +1 more source

Human Endogenous Retroviruses and Diseases

MedComm, Volume 6, Issue 11, November 2025.
Human endogenous retroviruses (HERVs), remnants of ancient retroviral integrations into the human genome, are modulated by viral infections, genetic inheritance, and triggers including environmental factors, epigenetic dysregulation, oncogene activation, and aging.
Can Chen, Yanru Cui, Shixiang Wang, Yuze Yang, Zunpeng Liu, Suhan Jin, Fangqian Shen, Udo Gaipl, Hu Ma, Jian‐Guo Zhou   +9 more
wiley   +1 more source

Tuberculosis transmission in Northwest of Iran: Using MIRU-VNTR, ETR-VNTR and IS6110-RFLP methods

Infection, Genetics and Evolution, 2011
Tuberculosis is the main cause for adults' death from a single infectious agent killing about 2 million people every year. Identifying the source of transmission infection is necessary to decrease tuberculosis. In this study we used IS6110-RFLP, MIRU-VNTR and ETR-VNTR methods to determine transmission dynamic of tuberculosis in Northwest of Iran from ...
Mohammad, Asgharzadeh, Hossein Samadi, Kafil, Ali Amoghi, Roudsary, Gholam Reza, Hanifi   +3 more
openaire   +2 more sources

Genetic Basis of the Negative Response to the Use of Triptans for the Treatment of Migraine—A Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 15, Issue 10, October 2025.
To systematize the genetic basis correctly associated with nonresponse to triptan, we revised etiological studies on Web of Science, Embase, and PubMed until 2023. We found that only polymorphisms in the SLC6A4, 5‐HT1B, and COMT genes have a stronger association with this condition. More robust studies are needed to increase this certainty.
Victoria Gomes Andreata, Ruan Pablo Duarte Freitas, Jéssica da Silva Nascimento, Patrícia Sodré Araújo, Felipe Eustáquio dos Santos Guedes, João Vítor Benjamim Pires, Narel Moita Carneiro Nogueira Falcão, Natasha da Silva Leitão, Alcylene Carla de Jesus dos Santos, Ana Patrícia Pascoal Queiroz, Astria Ferrão Dias Gonzales, Maica Matos Leão, Emília Katiane Embiruçu de Araújo Leão, Juliana Côrtes Freitas, Acássia Benjamim Leal Pires   +14 more
wiley   +1 more source

Genetic Heterogeneity of Francisella tularensis Subspecies mediasiatica Strains

Проблемы особо опасных инфекций
The aim of the study was to conduct comparative phylogenetic analysis of Francisella tularensis subsp. mediasiatica strains isolated in different territories of contemporary Republics of Kazakhstan, Uzbekistan, Altai Territory, and the Altai Republic in ...
V. M. Sorokin, N. V. Pavlovich, M. V. Tsimbalistova, N. V. Aronova, A. S. Vodop’yanov, R. V. Pisanov   +5 more
doaj   +1 more source

Humanized Mouse Models for Type 1 Diabetes

Current Protocols, Volume 5, Issue 10, October 2025.
Abstract T cell–mediated autoimmune type 1 diabetes (T1D) is under complex polygenic control in both humans and the NOD mouse model. However, in both species, particular major histocompatibility complex (MHC; designated HLA in humans) haplotypes provide the primary T1D risk factor. Both MHC/HLA class I and II variants interactively contribute to T1D by
David V. Serreze, Marissa Tousey‐Pfarrer, Jeremy J. Racine   +2 more
wiley   +1 more source

RepeatOBserver: Tandem Repeat Visualisation and Putative Centromere Detection

Molecular Ecology Resources, Volume 25, Issue 7, October 2025.
ABSTRACT Tandem repeats play an important role in centromere structure, subtelomeric regions, DNA methylation, recombination and the regulation of gene activity. Analysis of their distribution in genomes offers a potential means for predicting putative centromere locations, which continues to be a challenge for genome annotation.
Cassandra Elphinstone, Rob Elphinstone, Marco Todesco, Loren H. Rieseberg   +3 more
wiley   +1 more source

Characterization of three VNTR systems at D21S112

Genomics, 1992
D21S112 is a highly polymorphic marker on the long arm of chromosome 21. Our analysis of this locus indicated the presence of three VNTR systems. We estimated the heterozygosity of each system and sequenced one of the repetitive regions. Utilizing PCR, we demonstrated that the sequenced VNTR is responsible for the system with the highest level of ...
N, Takaesu, S, Newfeld, T, Hassold
openaire   +2 more sources

Spatio-Temporal Analysis of the Tularemia Agent Population in the Rostov Region, DPR, LPR and Ukraine from 1943 to 2023

Проблемы особо опасных инфекций
The aim of the study was to conduct spatio-temporal retrospective and operational genetic analysis of the tularemia agent population in the Rostov Region, Donetsk People’s Republic (DPR), Lugansk PR and Ukraine in the period of 1943–2023.
V. M. Sorokin, N. V. Pavlovich, M. V. Tsimbalistova, N. V. Aronova, A. S. Vodop’yanov, R. V. Pisanov, A. K. Noskov   +6 more
doaj   +1 more source

Genotyping of genetically monomorphic bacteria: DNA sequencing in Mycobacterium tuberculosis highlights the limitations of current methodologies.

PLoS ONE, 2009
Because genetically monomorphic bacterial pathogens harbour little DNA sequence diversity, most current genotyping techniques used to study the epidemiology of these organisms are based on mobile or repetitive genetic elements. Molecular markers commonly
Iñaki Comas, Susanne Homolka, Stefan Niemann, Sebastien Gagneux   +3 more
doaj   +1 more source